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Vertex Pharmaceuticals

1,747 hedge funds and large institutions have $119B invested in Vertex Pharmaceuticals in 2026 Q2 according to their latest regulatory filings, with 191 funds opening new positions, 704 increasing their positions, 616 reducing their positions, and 109 closing their positions.

New
Increased
Maintained
Reduced
Closed

75% more first-time investments, than exits

New positions opened: 191 | Existing positions closed: 109

14% more repeat investments, than reductions

Existing positions increased: 704 | Existing positions reduced: 616

13% more capital invested

Capital invested by funds: $106B → $119B (+$13.4B)

3% more funds holding

Funds holding: 1,6951,747 (+52)

1.38% more ownership

Funds ownership: 93.56%94.94% (+1.4%)

9% more call options, than puts

Call options by funds: $853M | Put options by funds: $783M

29% less funds holding in top 10

Funds holding in top 10: 1712 (-5)

Holders
1,747
Holders Change
+52
Holders Change %
+3.07%
% of All Funds
21.1%
Holding in Top 10
12
Holding in Top 10 Change
-5
Holding in Top 10 Change %
-29.41%
% of All Funds
0.14%
New
191
Increased
704
Reduced
616
Closed
109
Calls
$853M
Puts
$783M
Net Calls
+$69.7M
Net Calls Change
-$97.3M
Name Holding Trade Value Shares
Change
Change in
Stake
SC
1601
SouthState Corp
Florida
$22.4K -$886 -2 -4%
BH
1602
Burk Holdings
Oklahoma
$22.4K
MAM
1603
Marquette Asset Management
Minnesota
$22.4K +$1.33K +3 +7%
IWM
1604
IMG Wealth Management
Florida
$22.4K +$3.54K +8 +22%
PS
1605
Planning Strategies
Pennsylvania
$22.4K +$19.9K +45 New
DIP
1606
DT Investment Partners
Pennsylvania
$21.9K
PWMG
1607
Private Wealth Management Group
New Jersey
$19.9K
CCMI
1608
Creative Capital Management Investments
California
$19.9K +$7.09K +16 +67%
GWS
1609
Greykasell Wealth Strategies
California
$18.9K -$3.99K -9 -19%
HWA
1610
Heritage Wealth Advisors
Virginia
$18.9K
TC
1611
Trust Company
Kansas
$18.9K
ITIM
1612
Indiana Trust & Investment Management
Indiana
$17.4K
VWA
1613
Valued Wealth Advisors
Utah
$17.2K -$886 -2 -5%
BHWM
1614
Beaird Harris Wealth Management
Texas
$16.4K
OCM
1615
Orion Capital Management
California
$15.9K
LAM
1616
Lummis Asset Management
Texas
$15.9K +$1.33K +3 +10%
CJ
1617
Caitlin John
Michigan
$15.4K
FIM
1618
FWL Investment Management
Texas
$14.9K
FFA
1619
Frazier Financial Advisors
Ohio
$14.4K
SWA
1620
Strategic Wealth Advisors
Arizona
$14K
PG
1621
Proffitt & Goodson
Tennessee
$13.9K
RS
1622
Rakuten Securities
Japan
$13.9K +$3.54K +8 +40%
DPW
1623
DiNuzzo Private Wealth
Pennsylvania
$13.4K
VERPA
1624
Virginia Estate & Retirement Planning Advisors
Virginia
$13.4K
BHWM
1625
Bay Harbor Wealth Management
Maryland
$13.4K +$3.99K +9 +50%

VRTX Hedge Fund Activity: Q2 2026 in Review

1,747 of the 8,279 institutional investors tracked by Wall St. Rank reported a position in Vertex Pharmaceuticals (VRTX) for Q2 2026, worth a combined $119B — up 13% from $106B a quarter earlier.

Buyers outnumbered sellers: 191 funds opened new VRTX positions and 109 closed out — a net gain of 82 holders — while 704 added to existing stakes and 616 trimmed.

The largest buyer was Franklin Resources, adding an estimated $1.24B. The largest seller was Capital Research Global Investors, cutting an estimated $725M.

  • 1,747 institutional investors held Vertex Pharmaceuticals (VRTX) as of Q2 2026, up from 1,695 in Q1 2026.
  • Funds reported $119B of Vertex Pharmaceuticals stock for Q2 2026, up 13% quarter-over-quarter.
  • 191 funds opened new Vertex Pharmaceuticals positions in Q2 2026 and 109 closed out, a net change of +82 holders.
  • The largest Vertex Pharmaceuticals buyer in Q2 2026 was Franklin Resources, an estimated $1.24B added.
  • The largest Vertex Pharmaceuticals seller in Q2 2026 was Capital Research Global Investors, an estimated $725M sold.

Based on aggregated 13F filings for Q2 2026.