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Vertex Pharmaceuticals
VRTX

Overview Fund Activity

1,536 hedge funds and large institutions have $107B invested in Vertex Pharmaceuticals in 2025 Q2 according to their latest regulatory filings, with 117 funds opening new positions, 606 increasing their positions, 605 reducing their positions, and 145 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
1,536
Holders Change
-59
Holders Change %
-3.7%
% of All Funds
20.58%
Holding in Top 10
16
Holding in Top 10 Change
-10
Holding in Top 10 Change %
-38.46%
% of All Funds
0.21%
New
117
Increased
606
Reduced
605
Closed
145
Calls
$930M
Puts
$554M
Net Calls
+$376M
Net Calls Change
+$202M

Top Buyers

1
Capital International Investors
Capital International Investors
California
+$884M
2
Victory Capital Management
Victory Capital Management
Texas
+$836M
3
Capital Research Global Investors
Capital Research Global Investors
California
+$700M
4
Jennison Associates
Jennison Associates
New York
+$485M
5
UBS AM
UBS AM
Illinois
+$226M

Top Sellers

1
Amundi
Amundi
France
-$898M
2
JPMorgan Chase & Co
JPMorgan Chase & Co
New York
-$840M
3
Fidelity Investments
Fidelity Investments
Massachusetts
-$588M
4
Massachusetts Financial Services
Massachusetts Financial Services
Massachusetts
-$330M
5
Wellington Management Group
Wellington Management Group
Massachusetts
-$286M
Name Holding Trade Value Shares
Change 		Shares
Change %
PAMP
1551
Polar Asset Management Partners
Ontario, Canada
– -$10.5M -21,594 Closed
SFI
1552
Susquehanna Fundamental Investments
Pennsylvania
– -$9.69M -19,986 Closed
LOAME
1553
Lombard Odier Asset Management (Europe)
United Kingdom
– -$9.66M -19,930 Closed
LF
1554
Longbow Finance
Switzerland
– -$9.06M -18,686 Closed
Jane Street
1555
Jane Street
New York
– -$7.28M -15,008 Closed
QIM
1556
Quantitative Investment Management
Virginia
– -$7.27M -14,997 Closed
CCM
1557
Cinctive Capital Management
New York
– -$6.73M -13,891 Closed
AIMCA
1558
Alberta Investment Management Corp (AIMCo)
Alberta, Canada
– -$6.15M -12,686 Closed
SC
1559
SummitTX Capital
Texas
– -$5.69M -11,743 Closed
VF
1560
Virtu Financial
New York
– -$4.39M -9,064 Closed
Twin Tree Management
1561
Twin Tree Management
Texas
– -$4.25M -8,773 Closed
CCB
1562
Cutter & Co Brokerage
Missouri
– -$4.08M -8,407 Closed
AC
1563
Allstate Corporation
Illinois
– -$3.63M -7,487 Closed
Fiera Capital (Canada)
1564
Fiera Capital (Canada)
Quebec, Canada
– -$3.44M -7,092 Closed
WI
1565
Wahed Invest
New York
– -$3.23M -6,663 Closed
CIC
1566
Chase Investment Counsel
Virginia
– -$3.2M -6,596 Closed
TPM
1567
Triasima Portfolio Management
Quebec, Canada
– -$3.01M -6,213 Closed
USAA
1568
United Services Automobile Association
Texas
– -$2.93M -5,953 Closed
LP
1569
LMR Partners
United Kingdom
– -$2.86M -5,889 Closed
PCM
1570
Prelude Capital Management
New York
– -$2.73M -5,632 Closed
AAF
1571
Andra AP-fonden
Sweden
– -$2.67M -5,500 Closed
ECM
1572
Element Capital Management
New York
– -$2.64M -5,448 Closed
Two Sigma Investments
1573
Two Sigma Investments
New York
– -$2M -4,121 Closed
CFA
1574
Camarda Financial Advisors
Florida
– -$1.74M -3,597 Closed
AFCM
1575
Applied Finance Capital Management
Puerto Rico
– -$1.68M -3,459 Closed
61 62
63
64 65