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Vertex Pharmaceuticals

1,747 hedge funds and large institutions have $119B invested in Vertex Pharmaceuticals in 2026 Q2 according to their latest regulatory filings, with 191 funds opening new positions, 704 increasing their positions, 616 reducing their positions, and 109 closing their positions.

New
Increased
Maintained
Reduced
Closed

75% more first-time investments, than exits

New positions opened: 191 | Existing positions closed: 109

14% more repeat investments, than reductions

Existing positions increased: 704 | Existing positions reduced: 616

13% more capital invested

Capital invested by funds: $106B → $119B (+$13.4B)

3% more funds holding

Funds holding: 1,6951,747 (+52)

1.38% more ownership

Funds ownership: 93.56%94.94% (+1.4%)

9% more call options, than puts

Call options by funds: $853M | Put options by funds: $783M

29% less funds holding in top 10

Funds holding in top 10: 1712 (-5)

Holders
1,747
Holders Change
+52
Holders Change %
+3.07%
% of All Funds
21.1%
Holding in Top 10
12
Holding in Top 10 Change
-5
Holding in Top 10 Change %
-29.41%
% of All Funds
0.14%
New
191
Increased
704
Reduced
616
Closed
109
Calls
$853M
Puts
$783M
Net Calls
+$69.7M
Net Calls Change
-$97.3M
Name Holding Trade Value Shares
Change
Change in
Stake
FMII
1501
Farmers & Merchants Investments Inc
Nebraska
$84.4K
GIA
1502
GHP Investment Advisors
Colorado
$83.6K
SGK
1503
Steigerwald Gordon & Koch
Virginia
$83K
CSB
1504
City State Bank
Iowa
$79.5K
SL
1505
Salomon & Ludwin
Virginia
$79.2K +$16.8K +38 +31%
BCM
1506
Boreal Capital Management
Florida
$79K
PP
1507
PFS Partners
New Jersey
$78.5K
VIS
1508
Vega Investment Solutions
France
$77K +$36.3K +82 +112%
MUMSS
1509
Mitsubishi UFJ Morgan Stanley Securities
Japan
$75K -$116K -262 -63%
TFGT
1510
TS Financial Group (TSFG)
Illinois
$75K +$19.5K +44 +41%
CCC
1511
Chelsea Counsel Company
California
$74.5K
BIA
1512
Bell Investment Advisors
California
$74.5K +$9.31K +21 +16%
DJSG
1513
D.J. St. Germain
Massachusetts
$73.5K
KFA
1514
Kelleher Financial Advisors
New York
$72.5K +$20.4K +46 +46%
IUHSA
1515
Itau Unibanco Holding S.A.
Brazil
$70.5K
MB
1516
MidFirst Bank
Oklahoma
$68.5K +$12.4K +28 +25%
JFGIW
1517
Johnson Financial Group Inc (Wisconsin)
Wisconsin
$66.6K -$90.4K -204 -60%
CCWM
1518
Cassaday & Co Wealth Management
Virginia
$64.6K -$14.2K -32 -20%
AEPWM
1519
Atlantic Edge Private Wealth Management
Florida
$62.1K
OC
1520
Oakworth Capital
Alabama
$61.7K -$55.4K -125 -50%
CPG
1521
Cornerstone Planning Group
New Jersey
$61.4K +$6.21K +14 +12%
CAC
1522
Core Alternative Capital
Georgia
$61.1K
KG
1523
Kilter Group
New York
$60.6K +$886 +2 +2%
GCM
1524
Gables Capital Management
Florida
$60.1K
SWIM
1525
Smallwood Wealth Investment Management
New Jersey
$60.1K

VRTX Hedge Fund Activity: Q2 2026 in Review

1,747 of the 8,279 institutional investors tracked by Wall St. Rank reported a position in Vertex Pharmaceuticals (VRTX) for Q2 2026, worth a combined $119B — up 13% from $106B a quarter earlier.

Buyers outnumbered sellers: 191 funds opened new VRTX positions and 109 closed out — a net gain of 82 holders — while 704 added to existing stakes and 616 trimmed.

The largest buyer was Franklin Resources, adding an estimated $1.24B. The largest seller was Capital Research Global Investors, cutting an estimated $725M.

  • 1,747 institutional investors held Vertex Pharmaceuticals (VRTX) as of Q2 2026, up from 1,695 in Q1 2026.
  • Funds reported $119B of Vertex Pharmaceuticals stock for Q2 2026, up 13% quarter-over-quarter.
  • 191 funds opened new Vertex Pharmaceuticals positions in Q2 2026 and 109 closed out, a net change of +82 holders.
  • The largest Vertex Pharmaceuticals buyer in Q2 2026 was Franklin Resources, an estimated $1.24B added.
  • The largest Vertex Pharmaceuticals seller in Q2 2026 was Capital Research Global Investors, an estimated $725M sold.

Based on aggregated 13F filings for Q2 2026.