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Vertex Pharmaceuticals

1,747 hedge funds and large institutions have $119B invested in Vertex Pharmaceuticals in 2026 Q2 according to their latest regulatory filings, with 191 funds opening new positions, 704 increasing their positions, 616 reducing their positions, and 109 closing their positions.

New
Increased
Maintained
Reduced
Closed

75% more first-time investments, than exits

New positions opened: 191 | Existing positions closed: 109

14% more repeat investments, than reductions

Existing positions increased: 704 | Existing positions reduced: 616

13% more capital invested

Capital invested by funds: $106B → $119B (+$13.4B)

3% more funds holding

Funds holding: 1,6951,747 (+52)

1.38% more ownership

Funds ownership: 93.56%94.94% (+1.4%)

9% more call options, than puts

Call options by funds: $853M | Put options by funds: $783M

29% less funds holding in top 10

Funds holding in top 10: 1712 (-5)

Holders
1,747
Holders Change
+52
Holders Change %
+3.07%
% of All Funds
21.1%
Holding in Top 10
12
Holding in Top 10 Change
-5
Holding in Top 10 Change %
-29.41%
% of All Funds
0.14%
New
191
Increased
704
Reduced
616
Closed
109
Calls
$853M
Puts
$783M
Net Calls
+$69.7M
Net Calls Change
-$97.3M
Name Holding Trade Value Shares
Change
Change in
Stake
LI
1451
LRI Investments
Florida
$158K -$29.3K -66 -17%
TFM
1452
TFC Financial Management
Massachusetts
$157K +$3.99K +9 +3%
TWM
1453
Tripletail Wealth Management
Florida
$153K
WETS
1454
Wealth Enhancement Trust Services
South Dakota
$152K -$886 -2 -0.6%
QL
1455
Quarry LP
New York
$152K +$136K +306 New
EB
1456
Eastern Bank
Massachusetts
$152K -$25.3K -57 -16%
HNB
1457
Hilltop National Bank
Wyoming
$151K +$13.7K +31 +11%
TFA
1458
Toth Financial Advisory
Virginia
$149K -$2.66K -6 -2%
MO
1459
McMillan Office
Michigan
$149K
SOW
1460
State of Wyoming
Wyoming
$149K +$133K +300 New
Vanguard National Trust
1461
Vanguard National Trust
Pennsylvania
$146K
KFI
1462
Key Financial Inc
Pennsylvania
$144K
OCWP
1463
Owl Creek Wealth Partners
Colorado
$142K +$12.9K +29 +11%
MCP
1464
Miller Capital Partners
Michigan
$141K -$98.4K -222 -44%
RBC
1465
Roble Belko & Company
Pennsylvania
$139K
AWA
1466
Acumen Wealth Advisors
Tennessee
$135K +$7.98K +18 +7%
WA
1467
WPG Advisers
Maryland
$133K +$7.09K +16 +6%
GTAM
1468
Global Trust Asset Management
Florida
$130K -$4.43K -10 -4%
RDFA
1469
Ritter Daniher Financial Advisory
Ohio
$127K -$12K -27 -10%
SIM
1470
Synergy Investment Management
Florida
$124K +$89.5K +202 +381%
SG
1471
Sankala Group
Colorado
$123K
NS
1472
NBC Securities
Alabama
$122K -$443 -1 -0.4%
AFC
1473
Ares Financial Consulting
California
$122K +$2.22K +5 +2%
ITG
1474
Index Technologies Group
New York
$122K +$109K +245 New
TCOT
1475
Trust Company of Toledo
Ohio
$121K -$443 -1 -0.4%

VRTX Hedge Fund Activity: Q2 2026 in Review

1,747 of the 8,279 institutional investors tracked by Wall St. Rank reported a position in Vertex Pharmaceuticals (VRTX) for Q2 2026, worth a combined $119B — up 13% from $106B a quarter earlier.

Buyers outnumbered sellers: 191 funds opened new VRTX positions and 109 closed out — a net gain of 82 holders — while 704 added to existing stakes and 616 trimmed.

The largest buyer was Franklin Resources, adding an estimated $1.24B. The largest seller was Capital Research Global Investors, cutting an estimated $725M.

  • 1,747 institutional investors held Vertex Pharmaceuticals (VRTX) as of Q2 2026, up from 1,695 in Q1 2026.
  • Funds reported $119B of Vertex Pharmaceuticals stock for Q2 2026, up 13% quarter-over-quarter.
  • 191 funds opened new Vertex Pharmaceuticals positions in Q2 2026 and 109 closed out, a net change of +82 holders.
  • The largest Vertex Pharmaceuticals buyer in Q2 2026 was Franklin Resources, an estimated $1.24B added.
  • The largest Vertex Pharmaceuticals seller in Q2 2026 was Capital Research Global Investors, an estimated $725M sold.

Based on aggregated 13F filings for Q2 2026.