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Vertex Pharmaceuticals

1,747 hedge funds and large institutions have $119B invested in Vertex Pharmaceuticals in 2026 Q2 according to their latest regulatory filings, with 191 funds opening new positions, 704 increasing their positions, 616 reducing their positions, and 109 closing their positions.

New
Increased
Maintained
Reduced
Closed

75% more first-time investments, than exits

New positions opened: 191 | Existing positions closed: 109

14% more repeat investments, than reductions

Existing positions increased: 704 | Existing positions reduced: 616

13% more capital invested

Capital invested by funds: $106B → $119B (+$13.4B)

3% more funds holding

Funds holding: 1,6951,747 (+52)

1.38% more ownership

Funds ownership: 93.56%94.94% (+1.4%)

9% more call options, than puts

Call options by funds: $853M | Put options by funds: $783M

29% less funds holding in top 10

Funds holding in top 10: 1712 (-5)

Holders
1,747
Holders Change
+52
Holders Change %
+3.07%
% of All Funds
21.1%
Holding in Top 10
12
Holding in Top 10 Change
-5
Holding in Top 10 Change %
-29.41%
% of All Funds
0.14%
New
191
Increased
704
Reduced
616
Closed
109
Calls
$853M
Puts
$783M
Net Calls
+$69.7M
Net Calls Change
-$97.3M
Name Holding Trade Value Shares
Change
Change in
Stake
SH
1326
SLT Holdings
Arizona
$250K +$8.86K +20 +4%
BCM
1327
Brookstone Capital Management
Illinois
$248K +$1.33K +3 +0.6%
AFA
1328
Arlington Financial Advisors
California
$248K
BI
1329
Bramshill Investments
Florida
$248K
MG
1330
McHugh Group
Ohio
$248K
RCWM
1331
Royal Capital Wealth Management
Indiana
$248K +$222K +500 New
CB
1332
Community Bank
New York
$248K -$168K -380 -43%
DBRC
1333
D.B. Root & Company
Pennsylvania
$248K -$68.7K -155 -24%
FCG
1334
Fielder Capital Group
Tennessee
$248K -$34.1K -77 -13%
FFN
1335
Focus Financial Network
Minnesota
$247K +$2.22K +5 +1%
ST
1336
Smithfield Trust
Pennsylvania
$247K
BT
1337
Banque Transatlantique
France
$246K +$18.6K +42 +9%
SIC
1338
Salem Investment Counselors
North Carolina
$245K
EL
1339
EWA LLC
Pennsylvania
$245K +$5.32K +12 +3%
TLP
1340
Trinity Legacy Partners
Texas
$244K +$3.54K +8 +2%
AMCA
1341
Arthur M. Cohen & Associates
Illinois
$243K
QPWM
1342
Quadrant Private Wealth Management
Pennsylvania
$243K +$217K +489 New
5NPW
1343
55 North Private Wealth
Florida
$242K +$7.98K +18 +4%
JFGLC
1344
Johnson Financial Group LLC (Colorado)
Colorado
$241K +$215K +486 New
BTW
1345
Boston Trust Walden
Massachusetts
$241K
GPA
1346
Guerra Pan Advisors
New Jersey
$241K
LIM
1347
Loudon Investment Management
New Hampshire
$241K
CFO
1348
CVA Family Office
Colorado
$239K +$4.43K +10 +2%
LWA
1349
Legacy Wealth Advisors
Florida
$239K +$213K +481 New
VAG
1350
VisionPoint Advisory Group
Texas
$238K -$126K -285 -37%

VRTX Hedge Fund Activity: Q2 2026 in Review

1,747 of the 8,279 institutional investors tracked by Wall St. Rank reported a position in Vertex Pharmaceuticals (VRTX) for Q2 2026, worth a combined $119B — up 13% from $106B a quarter earlier.

Buyers outnumbered sellers: 191 funds opened new VRTX positions and 109 closed out — a net gain of 82 holders — while 704 added to existing stakes and 616 trimmed.

The largest buyer was Franklin Resources, adding an estimated $1.24B. The largest seller was Capital Research Global Investors, cutting an estimated $725M.

  • 1,747 institutional investors held Vertex Pharmaceuticals (VRTX) as of Q2 2026, up from 1,695 in Q1 2026.
  • Funds reported $119B of Vertex Pharmaceuticals stock for Q2 2026, up 13% quarter-over-quarter.
  • 191 funds opened new Vertex Pharmaceuticals positions in Q2 2026 and 109 closed out, a net change of +82 holders.
  • The largest Vertex Pharmaceuticals buyer in Q2 2026 was Franklin Resources, an estimated $1.24B added.
  • The largest Vertex Pharmaceuticals seller in Q2 2026 was Capital Research Global Investors, an estimated $725M sold.

Based on aggregated 13F filings for Q2 2026.