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Vertex Pharmaceuticals

1,747 hedge funds and large institutions have $119B invested in Vertex Pharmaceuticals in 2026 Q2 according to their latest regulatory filings, with 191 funds opening new positions, 704 increasing their positions, 616 reducing their positions, and 109 closing their positions.

New
Increased
Maintained
Reduced
Closed

75% more first-time investments, than exits

New positions opened: 191 | Existing positions closed: 109

14% more repeat investments, than reductions

Existing positions increased: 704 | Existing positions reduced: 616

13% more capital invested

Capital invested by funds: $106B → $119B (+$13.4B)

3% more funds holding

Funds holding: 1,6951,747 (+52)

1.38% more ownership

Funds ownership: 93.56%94.94% (+1.4%)

9% more call options, than puts

Call options by funds: $853M | Put options by funds: $783M

29% less funds holding in top 10

Funds holding in top 10: 1712 (-5)

Holders
1,747
Holders Change
+52
Holders Change %
+3.07%
% of All Funds
21.1%
Holding in Top 10
12
Holding in Top 10 Change
-5
Holding in Top 10 Change %
-29.41%
% of All Funds
0.14%
New
191
Increased
704
Reduced
616
Closed
109
Calls
$853M
Puts
$783M
Net Calls
+$69.7M
Net Calls Change
-$97.3M
Name Holding Trade Value Shares
Change
Change in
Stake
KFAS
1276
Keating Financial Advisory Services
Kansas
$278K +$63.4K +143 +34%
DW30
1277
Drucker Wealth 3.0
New Jersey
$277K +$18.6K +42 +8%
AA
1278
Armis Advisers
Georgia
$276K +$12K +27 +5%
PWMG
1279
Prestige Wealth Management Group
New Jersey
$276K -$129K -291 -34%
CSPIA
1280
Cary Street Partners Investment Advisory
Virginia
$276K -$5.76K -13 -2%
TGAM
1281
TBH Global Asset Management
Tennessee
$275K -$6.65K -15 -3%
NF
1282
Nvest Financial
New Hampshire
$275K
GAA
1283
Green Alpha Advisors
Colorado
$274K +$2.66K +6 +1%
QFW
1284
QTR Family Wealth
Florida
$273K +$244K +550 New
KAS
1285
KPP Advisory Services
Kentucky
$273K -$18.6K -42 -7%
PTC
1286
Private Trust Company
Ohio
$272K +$6.65K +15 +3%
1WA
1287
180 Wealth Advisors
Washington
$272K -$12K -27 -5%
KA
1288
Klingman & Associates
New York
$272K +$7.98K +18 +3%
SWM
1289
SHP Wealth Management
Massachusetts
$270K +$8.86K +20 +4%
OFO
1290
OneAscent Family Office
Alabama
$270K +$241K +544 New
MAM
1291
Mainsail Asset Management
Alabama
$270K +$44.3K +100 +22%
ML
1292
McAdam LLC
Pennsylvania
$270K +$241K +543 New
BLFG
1293
Brian Low Financial Group
Louisiana
$269K +$2.66K +6 +1%
UAG
1294
United Advisor Group
Ohio
$268K -$2.66K -6 -1%
CT
1295
Coastline Trust
Rhode Island
$267K
WT
1296
Washington Trust
Rhode Island
$267K
MKA
1297
M. Kulyk & Associates
Georgia
$267K +$23K +52 +11%
MFC
1298
Morris Financial Concepts
South Carolina
$266K +$2.66K +6 +1%
HDIM
1299
Hanson & Doremus Investment Management
Vermont
$265K -$8.86K -20 -4%
Vanguard Capital Wealth Advisors
1300
Vanguard Capital Wealth Advisors
Colorado
$263K

VRTX Hedge Fund Activity: Q2 2026 in Review

1,747 of the 8,279 institutional investors tracked by Wall St. Rank reported a position in Vertex Pharmaceuticals (VRTX) for Q2 2026, worth a combined $119B — up 13% from $106B a quarter earlier.

Buyers outnumbered sellers: 191 funds opened new VRTX positions and 109 closed out — a net gain of 82 holders — while 704 added to existing stakes and 616 trimmed.

The largest buyer was Franklin Resources, adding an estimated $1.24B. The largest seller was Capital Research Global Investors, cutting an estimated $725M.

  • 1,747 institutional investors held Vertex Pharmaceuticals (VRTX) as of Q2 2026, up from 1,695 in Q1 2026.
  • Funds reported $119B of Vertex Pharmaceuticals stock for Q2 2026, up 13% quarter-over-quarter.
  • 191 funds opened new Vertex Pharmaceuticals positions in Q2 2026 and 109 closed out, a net change of +82 holders.
  • The largest Vertex Pharmaceuticals buyer in Q2 2026 was Franklin Resources, an estimated $1.24B added.
  • The largest Vertex Pharmaceuticals seller in Q2 2026 was Capital Research Global Investors, an estimated $725M sold.

Based on aggregated 13F filings for Q2 2026.