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Vertex Pharmaceuticals

1,747 hedge funds and large institutions have $119B invested in Vertex Pharmaceuticals in 2026 Q2 according to their latest regulatory filings, with 191 funds opening new positions, 704 increasing their positions, 616 reducing their positions, and 109 closing their positions.

New
Increased
Maintained
Reduced
Closed

75% more first-time investments, than exits

New positions opened: 191 | Existing positions closed: 109

14% more repeat investments, than reductions

Existing positions increased: 704 | Existing positions reduced: 616

13% more capital invested

Capital invested by funds: $106B → $119B (+$13.4B)

3% more funds holding

Funds holding: 1,6951,747 (+52)

1.38% more ownership

Funds ownership: 93.56%94.94% (+1.4%)

9% more call options, than puts

Call options by funds: $853M | Put options by funds: $783M

29% less funds holding in top 10

Funds holding in top 10: 1712 (-5)

Holders
1,747
Holders Change
+52
Holders Change %
+3.07%
% of All Funds
21.1%
Holding in Top 10
12
Holding in Top 10 Change
-5
Holding in Top 10 Change %
-29.41%
% of All Funds
0.14%
New
191
Increased
704
Reduced
616
Closed
109
Calls
$853M
Puts
$783M
Net Calls
+$69.7M
Net Calls Change
-$97.3M
Name Holding Trade Value Shares
Change
Change in
Stake
CAM
1226
Costello Asset Management
Pennsylvania
$312K +$17.7K +40 +7%
NRC
1227
New Republic Capital
North Carolina
$312K +$42.5K +96 +18%
MFIM
1228
Mesirow Financial Investment Management
Illinois
$312K -$22.2K -50 -7%
EPW
1229
Elevated Private Wealth
Wisconsin
$312K +$278K +628 New
CCA
1230
Childress Capital Advisors
Texas
$312K +$8.42K +19 +3%
WHG
1231
Westwood Holdings Group
Texas
$311K +$277K +626 New
MT
1232
Midwest Trust
Kansas
$308K +$10.2K +23 +4%
AP
1233
Anchyra Partners
Georgia
$308K +$7.98K +18 +3%
MHC
1234
May Hill Capital
Massachusetts
$306K +$20.4K +46 +8%
GKFF
1235
George Kaiser Family Foundation
Oklahoma
$306K -$112K -253 -29%
PGCM
1236
Prescott Group Capital Management
Oklahoma
$306K -$112K -253 -29%
SHFG
1237
S Harris Financial Group
Texas
$305K -$443 -1 -0.2%
SN
1238
Sittner & Nelson
Oregon
$305K
SLG
1239
Stanley-Laman Group
Pennsylvania
$305K +$27K +61 +11%
MW
1240
MBL Wealth
North Carolina
$304K +$24.4K +55 +10%
KMWM
1241
Keudell/Morrison Wealth Management
Oregon
$304K
TC
1242
Tannin Capital
North Carolina
$303K
SWM
1243
Sandro Wealth Management
New Jersey
$303K +$14.2K +32 +6%
KIA
1244
Kraematon Investment Advisors
Massachusetts
$302K
SFG
1245
SNS Financial Group
Minnesota
$302K +$269K +607 New
WSWA
1246
Warren Street Wealth Advisors
California
$301K +$22.6K +51 +9%
AWM
1247
Aries Wealth Management
Maine
$301K
AWM
1248
Aprio Wealth Management
Georgia
$298K -$7.53K -17 -3%
FAB
1249
First American Bank
Illinois
$298K -$6.65K -15 -2%
Parallax Volatility Advisers
1250
Parallax Volatility Advisers
California
$298K +$265K +599 New

VRTX Hedge Fund Activity: Q2 2026 in Review

1,747 of the 8,279 institutional investors tracked by Wall St. Rank reported a position in Vertex Pharmaceuticals (VRTX) for Q2 2026, worth a combined $119B — up 13% from $106B a quarter earlier.

Buyers outnumbered sellers: 191 funds opened new VRTX positions and 109 closed out — a net gain of 82 holders — while 704 added to existing stakes and 616 trimmed.

The largest buyer was Franklin Resources, adding an estimated $1.24B. The largest seller was Capital Research Global Investors, cutting an estimated $725M.

  • 1,747 institutional investors held Vertex Pharmaceuticals (VRTX) as of Q2 2026, up from 1,695 in Q1 2026.
  • Funds reported $119B of Vertex Pharmaceuticals stock for Q2 2026, up 13% quarter-over-quarter.
  • 191 funds opened new Vertex Pharmaceuticals positions in Q2 2026 and 109 closed out, a net change of +82 holders.
  • The largest Vertex Pharmaceuticals buyer in Q2 2026 was Franklin Resources, an estimated $1.24B added.
  • The largest Vertex Pharmaceuticals seller in Q2 2026 was Capital Research Global Investors, an estimated $725M sold.

Based on aggregated 13F filings for Q2 2026.