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Vertex Pharmaceuticals

1,747 hedge funds and large institutions have $119B invested in Vertex Pharmaceuticals in 2026 Q2 according to their latest regulatory filings, with 191 funds opening new positions, 704 increasing their positions, 616 reducing their positions, and 109 closing their positions.

New
Increased
Maintained
Reduced
Closed

75% more first-time investments, than exits

New positions opened: 191 | Existing positions closed: 109

14% more repeat investments, than reductions

Existing positions increased: 704 | Existing positions reduced: 616

13% more capital invested

Capital invested by funds: $106B → $119B (+$13.4B)

3% more funds holding

Funds holding: 1,6951,747 (+52)

1.38% more ownership

Funds ownership: 93.56%94.94% (+1.4%)

9% more call options, than puts

Call options by funds: $853M | Put options by funds: $783M

29% less funds holding in top 10

Funds holding in top 10: 1712 (-5)

Holders
1,747
Holders Change
+52
Holders Change %
+3.07%
% of All Funds
21.1%
Holding in Top 10
12
Holding in Top 10 Change
-5
Holding in Top 10 Change %
-29.41%
% of All Funds
0.14%
New
191
Increased
704
Reduced
616
Closed
109
Calls
$853M
Puts
$783M
Net Calls
+$69.7M
Net Calls Change
-$97.3M
Name Holding Trade Value Shares
Change
Change in
Stake
ACM
1151
Arlington Capital Management
Illinois
$397K
GAA
1152
Guardian Asset Advisors
Pennsylvania
$397K +$12.9K +29 +4%
SL
1153
Sentinus LLC
Illinois
$397K +$82.4K +186 +30%
AWP
1154
Abacus Wealth Partners
California
$396K -$423K -955 -54%
BHC
1155
Bull Harbor Capital
Maryland
$395K +$353K +796 New
SB
1156
Strategic Blueprint
Georgia
$395K +$32.8K +74 +10%
TPI
1157
Trust Point Inc
Wisconsin
$394K +$9.31K +21 +3%
JTWM
1158
Jackson Thornton Wealth Management
Alabama
$393K +$351K +791 New
GWMR
1159
GC Wealth Management RIA
Massachusetts
$391K -$104K -234 -23%
CM
1160
Cercano Management
Washington
$387K
AFA
1161
AA Financial Advisors
Ohio
$387K -$62K -140 -15%
CCIA
1162
Cherry Creek Investment Advisors
Colorado
$382K -$249K -562 -42%
LG
1163
LaFleur & Godfrey
Michigan
$382K +$11.1K +25 +3%
CAM
1164
Cidel Asset Management
Ontario, Canada
$381K +$38.6K +87 +13%
DO
1165
denkapparat Operations
Germany
$380K
IIL
1166
Income Insurance Ltd
$380K
FS
1167
Financial Symmetry
North Carolina
$378K
BC
1168
Bridgefront Capital
Texas
$378K +$337K +760 New
NA
1169
Nautilus Advisors
California
$377K
GC
1170
Grimes & Company
Massachusetts
$377K +$49.2K +111 +17%
SFO
1171
Stenger Family Office
Illinois
$374K -$3.17M -7,148 -90%
IIA
1172
ICW Investment Advisors
Arizona
$373K -$6.21K -14 -2%
XPN
1173
XY Planning Network
Montana
$373K +$333K +751 New
CRB
1174
Chad R. Baker
$373K
SIA
1175
Strategic Investment Advisors
Michigan
$371K -$27.9K -63 -8%

VRTX Hedge Fund Activity: Q2 2026 in Review

1,747 of the 8,279 institutional investors tracked by Wall St. Rank reported a position in Vertex Pharmaceuticals (VRTX) for Q2 2026, worth a combined $119B — up 13% from $106B a quarter earlier.

Buyers outnumbered sellers: 191 funds opened new VRTX positions and 109 closed out — a net gain of 82 holders — while 704 added to existing stakes and 616 trimmed.

The largest buyer was Franklin Resources, adding an estimated $1.24B. The largest seller was Capital Research Global Investors, cutting an estimated $725M.

  • 1,747 institutional investors held Vertex Pharmaceuticals (VRTX) as of Q2 2026, up from 1,695 in Q1 2026.
  • Funds reported $119B of Vertex Pharmaceuticals stock for Q2 2026, up 13% quarter-over-quarter.
  • 191 funds opened new Vertex Pharmaceuticals positions in Q2 2026 and 109 closed out, a net change of +82 holders.
  • The largest Vertex Pharmaceuticals buyer in Q2 2026 was Franklin Resources, an estimated $1.24B added.
  • The largest Vertex Pharmaceuticals seller in Q2 2026 was Capital Research Global Investors, an estimated $725M sold.

Based on aggregated 13F filings for Q2 2026.