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Vertex Pharmaceuticals
VRTX

Overview Fund Activity

1,595 hedge funds and large institutions have $115B invested in Vertex Pharmaceuticals in 2025 Q1 according to their latest regulatory filings, with 209 funds opening new positions, 632 increasing their positions, 569 reducing their positions, and 126 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
1,595
Holders Change
+54
Holders Change %
+3.5%
% of All Funds
21.66%
Holding in Top 10
26
Holding in Top 10 Change
+10
Holding in Top 10 Change %
+62.5%
% of All Funds
0.35%
New
209
Increased
632
Reduced
569
Closed
126
Calls
$771M
Puts
$596M
Net Calls
+$175M
Net Calls Change
+$95M

Top Buyers

1
Capital Research Global Investors
Capital Research Global Investors
California
+$1.99B
2
JPMorgan Chase & Co
JPMorgan Chase & Co
New York
+$699M
3
T. Rowe Price Associates
T. Rowe Price Associates
Maryland
+$595M
4
Jennison Associates
Jennison Associates
New York
+$361M
5
Bank of America
Bank of America
North Carolina
+$216M

Top Sellers

1
Fidelity Investments
Fidelity Investments
Massachusetts
-$723M
2
Assenagon Asset Management
Assenagon Asset Management
Luxembourg
-$306M
3
Wellington Management Group
Wellington Management Group
Massachusetts
-$224M
4
Nordea Investment Management
Nordea Investment Management
Sweden
-$155M
5
Edgewood Management
Edgewood Management
Connecticut
-$152M
Name Holding Trade Value Shares
Change 		Shares
Change %
Holocene Advisors
1001
Holocene Advisors
New York
$590K -$159K -327 -21%
JF
1002
Jump Financial
Illinois
$586K -$889K -1,833 -60%
FCFC
1003
First Commonwealth Financial Corp
Pennsylvania
$583K +$328K +677 +129%
GITFIT
1004
Generali Investments Towarzystwo Funduszy Inwestycyjnych (TFI)
Poland
$582K – – –
FFS
1005
Founders Financial Securities
Maryland
$579K +$9.93K +20 +2%
SAM
1006
Simplify Asset Management
Nevada
$579K -$1.69M -3,494 -75%
APP
1007
Avantax Planning Partners
Iowa
$579K +$92.1K +190 +19%
KP
1008
Keel Point
Alabama
$574K +$105K +217 +22%
EW
1009
Evoke Wealth
California
$569K +$49.5K +102 +10%
MGIA
1010
Moneta Group Investment Advisors
Missouri
$568K +$54.3K +112 +11%
SIA
1011
SGL Investment Advisors
Montana
$568K -$4.3K -10 -0.8%
AWM
1012
AE Wealth Management
Kansas
$564K -$485 -1 -0.1%
PCS
1013
Personal CFO Solutions
New Jersey
$562K +$44.6K +92 +9%
PP
1014
PDS Planning
Ohio
$561K +$162K +334 +41%
BA
1015
Bridgewater Advisors
New York
$561K +$561K +1,113 New
WH
1016
Willner & Heller
California
$560K -$26.7K -55 -5%
LCM
1017
LCM Capital Management
Illinois
$555K +$34.4K +71 +7%
WJWM
1018
Williams Jones Wealth Management
New York
$550K – – –
RMDI
1019
R.M. Davis Inc
Maine
$548K +$41.7K +86 +8%
QWP
1020
Quotient Wealth Partners
Texas
$548K +$72.2K +149 +15%
SB
1021
SIG Brokerage
New York
$543K -$397K -818 -42%
GFP
1022
Gryphon Financial Partners
Ohio
$542K +$31K +64 +6%
FAFN
1023
First Affirmative Financial Network
Colorado
$540K +$60.6K +125 +13%
AFG
1024
Albion Financial Group
Utah
$540K -$110K -227 -17%
FFA
1025
Fragasso Financial Advisors
Pennsylvania
$539K -$116K -239 -18%
39 40
41
42 43