We are live on ! Find out more
VRTX icon

Vertex Pharmaceuticals

1,747 hedge funds and large institutions have $119B invested in Vertex Pharmaceuticals in 2026 Q2 according to their latest regulatory filings, with 191 funds opening new positions, 704 increasing their positions, 616 reducing their positions, and 109 closing their positions.

New
Increased
Maintained
Reduced
Closed

75% more first-time investments, than exits

New positions opened: 191 | Existing positions closed: 109

14% more repeat investments, than reductions

Existing positions increased: 704 | Existing positions reduced: 616

13% more capital invested

Capital invested by funds: $106B → $119B (+$13.4B)

3% more funds holding

Funds holding: 1,6951,747 (+52)

1.38% more ownership

Funds ownership: 93.56%94.94% (+1.4%)

9% more call options, than puts

Call options by funds: $853M | Put options by funds: $783M

29% less funds holding in top 10

Funds holding in top 10: 1712 (-5)

Holders
1,747
Holders Change
+52
Holders Change %
+3.07%
% of All Funds
21.1%
Holding in Top 10
12
Holding in Top 10 Change
-5
Holding in Top 10 Change %
-29.41%
% of All Funds
0.14%
New
191
Increased
704
Reduced
616
Closed
109
Calls
$853M
Puts
$783M
Net Calls
+$69.7M
Net Calls Change
-$97.3M
Name Holding Trade Value Shares
Change
Change in
Stake
BG
51
Bellevue Group
Switzerland
$287M -$45.8M -103,274 -15%
Neuberger Berman Group
52
Neuberger Berman Group
New York
$278M +$3.51M +7,923 +1%
Raymond James Financial
53
Raymond James Financial
Florida
$277M +$49.8M +112,380 +25%
Manulife (Manufacturers Life Insurance)
54
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$275M +$373K +842 +0.2%
Vanguard Global Advisers
55
Vanguard Global Advisers
Pennsylvania
$272M -$3.67M -8,270 -1%
Marshall Wace
56
Marshall Wace
United Kingdom
$270M +$101M +226,839 +72%
Pictet Asset Management
57
Pictet Asset Management
Switzerland
$268M +$89.4M +201,686 +60%
National Pension Service
58
National Pension Service
South Korea
$268M +$3.31M +7,461 +1%
Edgewood Management
59
Edgewood Management
Connecticut
$264M -$166M -374,126 -41%
SG Americas Securities
60
SG Americas Securities
New York
$260M +$207M +466,738 +819%
LCIP
61
Life Cycle Investment Partners
$255M +$32.7M +73,770 +17%
Citadel Advisors
62
Citadel Advisors
Florida
$254M +$75.8M +171,132 +50%
VOYA Investment Management
63
VOYA Investment Management
Georgia
$250M -$9.67M -21,828 -4%
Vanguard Asset Management
64
Vanguard Asset Management
$245M +$23M +52,009 +12%
Envestnet Asset Management
65
Envestnet Asset Management
Illinois
$242M -$7.06M -15,937 -3%
Millennium Management
66
Millennium Management
New York
$233M +$194M +437,587 +1,420%
DekaBank Deutsche Girozentrale
67
DekaBank Deutsche Girozentrale
Germany
$225M
Natixis Advisors
68
Natixis Advisors
Massachusetts
$223M -$46.7M -105,393 -19%
California Public Employees Retirement System
69
California Public Employees Retirement System
California
$222M -$24.8M -55,875 -11%
Massachusetts Financial Services
70
Massachusetts Financial Services
Massachusetts
$215M +$42.3M +95,551 +29%
Bank of Montreal
71
Bank of Montreal
Ontario, Canada
$212M +$16.4M +36,972 +9%
Chevy Chase Trust
72
Chevy Chase Trust
Maryland
$202M -$581K -1,312 -0.3%
Robeco Institutional Asset Management
73
Robeco Institutional Asset Management
Netherlands
$201M +$1.22M +2,752 +0.7%
RhumbLine Advisers
74
RhumbLine Advisers
Massachusetts
$197M -$11.9M -26,760 -6%
Adage Capital Partners
75
Adage Capital Partners
Massachusetts
$196M +$62.9M +141,974 +56%

VRTX Hedge Fund Activity: Q2 2026 in Review

1,747 of the 8,279 institutional investors tracked by Wall St. Rank reported a position in Vertex Pharmaceuticals (VRTX) for Q2 2026, worth a combined $119B — up 13% from $106B a quarter earlier.

Buyers outnumbered sellers: 191 funds opened new VRTX positions and 109 closed out — a net gain of 82 holders — while 704 added to existing stakes and 616 trimmed.

The largest buyer was Franklin Resources, adding an estimated $1.24B. The largest seller was Capital Research Global Investors, cutting an estimated $725M.

  • 1,747 institutional investors held Vertex Pharmaceuticals (VRTX) as of Q2 2026, up from 1,695 in Q1 2026.
  • Funds reported $119B of Vertex Pharmaceuticals stock for Q2 2026, up 13% quarter-over-quarter.
  • 191 funds opened new Vertex Pharmaceuticals positions in Q2 2026 and 109 closed out, a net change of +82 holders.
  • The largest Vertex Pharmaceuticals buyer in Q2 2026 was Franklin Resources, an estimated $1.24B added.
  • The largest Vertex Pharmaceuticals seller in Q2 2026 was Capital Research Global Investors, an estimated $725M sold.

Based on aggregated 13F filings for Q2 2026.