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Vertex Pharmaceuticals
VRTX

Overview Fund Activity

1,536 hedge funds and large institutions have $107B invested in Vertex Pharmaceuticals in 2025 Q2 according to their latest regulatory filings, with 117 funds opening new positions, 606 increasing their positions, 605 reducing their positions, and 145 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
1,536
Holders Change
-59
Holders Change %
-3.7%
% of All Funds
20.58%
Holding in Top 10
16
Holding in Top 10 Change
-10
Holding in Top 10 Change %
-38.46%
% of All Funds
0.21%
New
117
Increased
606
Reduced
605
Closed
145
Calls
$930M
Puts
$554M
Net Calls
+$376M
Net Calls Change
+$202M

Top Buyers

1
Capital International Investors
Capital International Investors
California
+$884M
2
Victory Capital Management
Victory Capital Management
Texas
+$836M
3
Capital Research Global Investors
Capital Research Global Investors
California
+$700M
4
Jennison Associates
Jennison Associates
New York
+$485M
5
UBS AM
UBS AM
Illinois
+$226M

Top Sellers

1
Amundi
Amundi
France
-$898M
2
JPMorgan Chase & Co
JPMorgan Chase & Co
New York
-$840M
3
Fidelity Investments
Fidelity Investments
Massachusetts
-$588M
4
Massachusetts Financial Services
Massachusetts Financial Services
Massachusetts
-$330M
5
Wellington Management Group
Wellington Management Group
Massachusetts
-$286M
Name Holding Trade Value Shares
Change 		Shares
Change %
Dimensional Fund Advisors
51
Dimensional Fund Advisors
Texas
$265M -$4.3M -9,652 -2%
Manulife (Manufacturers Life Insurance)
52
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$244M +$23.2K +52 +0%
Natixis Advisors
53
Natixis Advisors
Massachusetts
$241M -$27M -60,657 -10%
American Century Companies
54
American Century Companies
Missouri
$240M +$32.2M +72,391 +16%
BNP Paribas Financial Markets
55
BNP Paribas Financial Markets
France
$236M -$25.4M -57,149 -10%
Mitsubishi UFJ Asset Management
56
Mitsubishi UFJ Asset Management
Japan
$234M +$16M +35,858 +7%
Franklin Resources
57
Franklin Resources
California
$233M -$79.3M -178,201 -25%
DekaBank Deutsche Girozentrale
58
DekaBank Deutsche Girozentrale
Germany
$223M +$6.76M +15,328 +3%
Raymond James Financial
59
Raymond James Financial
Florida
$223M -$4.79M -10,765 -2%
National Pension Service
60
National Pension Service
South Korea
$222M -$27.2M -61,129 -11%
Lazard Asset Management
61
Lazard Asset Management
New York
$214M -$23.3M -52,287 -10%
TD Asset Management
62
TD Asset Management
Ontario, Canada
$207M -$9.21M -20,683 -4%
Neuberger Berman Group
63
Neuberger Berman Group
New York
$204M +$7.36M +16,522 +4%
RhumbLine Advisers
64
RhumbLine Advisers
Massachusetts
$202M +$1.49M +3,341 +0.7%
Envestnet Asset Management
65
Envestnet Asset Management
Illinois
$200M -$9.5M -21,340 -5%
BNP Paribas Asset Management
66
BNP Paribas Asset Management
France
$198M +$23.3M +52,446 +13%
BG
67
Bellevue Group
Switzerland
$197M +$12.7M +28,539 +7%
Chevy Chase Trust
68
Chevy Chase Trust
Maryland
$196M -$944K -2,121 -0.5%
Principal Financial Group
69
Principal Financial Group
Iowa
$182M -$2.03M -4,566 -1%
ProShare Advisors
70
ProShare Advisors
Maryland
$179M +$8.11M +18,214 +5%
California State Teachers Retirement System (CalSTRS)
71
California State Teachers Retirement System (CalSTRS)
California
$177M -$375K -843 -0.2%
Zurich Cantonal Bank
72
Zurich Cantonal Bank
Switzerland
$176M +$4.3M +9,661 +3%
Public Employees Retirement Association of Colorado
73
Public Employees Retirement Association of Colorado
Colorado
$175M -$11.4M -25,577 -6%
Bank Julius Baer & Co
74
Bank Julius Baer & Co
Switzerland
$174M +$12.7M +28,469 +8%
Bank of Montreal
75
Bank of Montreal
Ontario, Canada
$162M -$22.6M -50,652 -12%
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