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Vertex Pharmaceuticals

1,747 hedge funds and large institutions have $119B invested in Vertex Pharmaceuticals in 2026 Q2 according to their latest regulatory filings, with 191 funds opening new positions, 704 increasing their positions, 616 reducing their positions, and 109 closing their positions.

New
Increased
Maintained
Reduced
Closed

75% more first-time investments, than exits

New positions opened: 191 | Existing positions closed: 109

14% more repeat investments, than reductions

Existing positions increased: 704 | Existing positions reduced: 616

13% more capital invested

Capital invested by funds: $106B → $119B (+$13.4B)

3% more funds holding

Funds holding: 1,6951,747 (+52)

1.38% more ownership

Funds ownership: 93.56%94.94% (+1.4%)

9% more call options, than puts

Call options by funds: $853M | Put options by funds: $783M

29% less funds holding in top 10

Funds holding in top 10: 1712 (-5)

Holders
1,747
Holders Change
+52
Holders Change %
+3.07%
% of All Funds
21.1%
Holding in Top 10
12
Holding in Top 10 Change
-5
Holding in Top 10 Change %
-29.41%
% of All Funds
0.14%
New
191
Increased
704
Reduced
616
Closed
109
Calls
$853M
Puts
$783M
Net Calls
+$69.7M
Net Calls Change
-$97.3M
Name Holding Trade Value Shares
Change
Change in
Stake
SCI
676
S&CO Inc
Massachusetts
$2.04M
MIG
677
McGuire Investment Group
Rhode Island
$2.03M -$24.4K -55 -1%
JSSH
678
J. Safra Sarasin Holding
$2.02M
RIL
679
Rothschild Investment LLC
Illinois
$2.01M +$1.6M +3,601 +824%
TNBTD
680
Trustmark National Bank Trust Department
Mississippi
$2M -$74.5K -168 -4%
WC
681
Woodstock Corp
Massachusetts
$1.99M
BP
682
BNP Paribas
France
$1.99M -$128K -289 -7%
HWAM
683
Hennion & Walsh Asset Management
New Jersey
$1.98M -$20.4K -46 -1%
TCIIS
684
TIAA-CREF Individual & Institutional Services
New York
$1.96M -$51.4K -116 -3%
GRP
685
Global Retirement Partners
California
$1.95M +$1.74M +3,925 New
OWCM
686
One Wealth Capital Management
Arizona
$1.95M +$878K +1,980 +102%
AWM
687
AE Wealth Management
Kansas
$1.92M -$23.5K -53 -1%
CIA
688
Choate Investment Advisors
Massachusetts
$1.92M -$33.2K -75 -2%
HIIFS
689
Harel Insurance Investments & Financial Services
Israel
$1.91M +$365K +823 +27%
PMA
690
Prudent Man Advisors
Illinois
$1.9M +$177K +400 +12%
MCI
691
MRP Capital Investments
Georgia
$1.89M -$51K -115 -3%
IB
692
Intrust Bank
Kansas
$1.89M -$41.7K -94 -2%
VFA
693
Valeo Financial Advisors
Indiana
$1.88M +$127K +287 +8%
LGF
694
LGT Group Foundation
Liechtenstein
$1.87M -$31.5K -71 -2%
LD
695
Lipe & Dalton
New York
$1.87M -$104K -235 -6%
BAM
696
Belpointe Asset Management
Nevada
$1.86M +$428K +965 +35%
JKA
697
Jones Kertz & Associates
Minnesota
$1.85M -$122K -275 -7%
CP
698
CenterBook Partners
Connecticut
$1.85M +$1.65M +3,718 New
AG
699
Ascent Group
Virginia
$1.84M -$314K -709 -16%
SWA
700
SFMG Wealth Advisors
Texas
$1.82M -$71.8K -162 -4%

VRTX Hedge Fund Activity: Q2 2026 in Review

1,747 of the 8,279 institutional investors tracked by Wall St. Rank reported a position in Vertex Pharmaceuticals (VRTX) for Q2 2026, worth a combined $119B — up 13% from $106B a quarter earlier.

Buyers outnumbered sellers: 191 funds opened new VRTX positions and 109 closed out — a net gain of 82 holders — while 704 added to existing stakes and 616 trimmed.

The largest buyer was Franklin Resources, adding an estimated $1.24B. The largest seller was Capital Research Global Investors, cutting an estimated $725M.

  • 1,747 institutional investors held Vertex Pharmaceuticals (VRTX) as of Q2 2026, up from 1,695 in Q1 2026.
  • Funds reported $119B of Vertex Pharmaceuticals stock for Q2 2026, up 13% quarter-over-quarter.
  • 191 funds opened new Vertex Pharmaceuticals positions in Q2 2026 and 109 closed out, a net change of +82 holders.
  • The largest Vertex Pharmaceuticals buyer in Q2 2026 was Franklin Resources, an estimated $1.24B added.
  • The largest Vertex Pharmaceuticals seller in Q2 2026 was Capital Research Global Investors, an estimated $725M sold.

Based on aggregated 13F filings for Q2 2026.