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Vertex Pharmaceuticals

1,747 hedge funds and large institutions have $119B invested in Vertex Pharmaceuticals in 2026 Q2 according to their latest regulatory filings, with 191 funds opening new positions, 704 increasing their positions, 616 reducing their positions, and 109 closing their positions.

New
Increased
Maintained
Reduced
Closed

75% more first-time investments, than exits

New positions opened: 191 | Existing positions closed: 109

14% more repeat investments, than reductions

Existing positions increased: 704 | Existing positions reduced: 616

13% more capital invested

Capital invested by funds: $106B → $119B (+$13.4B)

3% more funds holding

Funds holding: 1,6951,747 (+52)

1.38% more ownership

Funds ownership: 93.56%94.94% (+1.4%)

9% more call options, than puts

Call options by funds: $853M | Put options by funds: $783M

29% less funds holding in top 10

Funds holding in top 10: 1712 (-5)

Holders
1,747
Holders Change
+52
Holders Change %
+3.07%
% of All Funds
21.1%
Holding in Top 10
12
Holding in Top 10 Change
-5
Holding in Top 10 Change %
-29.41%
% of All Funds
0.14%
New
191
Increased
704
Reduced
616
Closed
109
Calls
$853M
Puts
$783M
Net Calls
+$69.7M
Net Calls Change
-$97.3M
Name Holding Trade Value Shares
Change
Change in
Stake
GIM
626
Generali Investments Management
Slovenia
$2.45M +$691K +1,560 +46%
AA
627
ALPS Advisors
Colorado
$2.44M +$1.17M +2,649 +117%
SWP
628
Strategic Wealth Partners
Ohio
$2.38M -$121K -274 -5%
CCG
629
Ceeto Capital Group
Florida
$2.36M
MWC
630
MBM Wealth Consultants
Missouri
$2.36M +$266K +600 +14%
WS
631
Wedbush Securities
California
$2.36M -$298K -672 -12%
DBG
632
De Burlo Group
Massachusetts
$2.35M -$6.65K -15 -0.3%
RWM
633
Ritholtz Wealth Management
New York
$2.34M -$62.5K -141 -3%
LCM
634
Laurion Capital Management
New York
$2.34M +$2.09M +4,706 New
TGIA
635
Torrey Growth & Income Advisors
California
$2.34M
OA
636
Oak Associates
Ohio
$2.32M
WAM
637
Weiss Asset Management
Massachusetts
$2.32M +$2.07M +4,677 New
MYLI
638
Meiji Yasuda Life Insurance
Japan
$2.32M -$147K -332 -7%
HIMS
639
Hager Investment Management Services
New Hampshire
$2.32M -$186K -420 -8%
AAP
640
Arax Advisory Partners
Colorado
$2.32M +$1.44M +3,239 +228%
WAP
641
Wealthcare Advisory Partners
Pennsylvania
$2.3M -$95.3K -215 -4%
CIM
642
Cambria Investment Management
California
$2.28M +$371K +838 +22%
GI
643
GLOBALT Investments
Georgia
$2.28M -$84.2K -190 -4%
SAM
644
Smartleaf Asset Management
Massachusetts
$2.27M
FDP
645
Financiere des Professionnels
Quebec, Canada
$2.26M -$57.2K -129 -3%
DADC
646
D.A. Davidson & Co
Montana
$2.26M -$262K -592 -12%
MG
647
Mather Group
Illinois
$2.24M +$34.6K +78 +2%
CA
648
Clearstead Advisors
Ohio
$2.24M +$480K +1,083 +32%
IBOK
649
Independence Bank of Kentucky
Kentucky
$2.24M +$1.6M +3,613 +405%
AW
650
Alaethes Wealth
Nevada
$2.24M +$245K +553 +14%

VRTX Hedge Fund Activity: Q2 2026 in Review

1,747 of the 8,279 institutional investors tracked by Wall St. Rank reported a position in Vertex Pharmaceuticals (VRTX) for Q2 2026, worth a combined $119B — up 13% from $106B a quarter earlier.

Buyers outnumbered sellers: 191 funds opened new VRTX positions and 109 closed out — a net gain of 82 holders — while 704 added to existing stakes and 616 trimmed.

The largest buyer was Franklin Resources, adding an estimated $1.24B. The largest seller was Capital Research Global Investors, cutting an estimated $725M.

  • 1,747 institutional investors held Vertex Pharmaceuticals (VRTX) as of Q2 2026, up from 1,695 in Q1 2026.
  • Funds reported $119B of Vertex Pharmaceuticals stock for Q2 2026, up 13% quarter-over-quarter.
  • 191 funds opened new Vertex Pharmaceuticals positions in Q2 2026 and 109 closed out, a net change of +82 holders.
  • The largest Vertex Pharmaceuticals buyer in Q2 2026 was Franklin Resources, an estimated $1.24B added.
  • The largest Vertex Pharmaceuticals seller in Q2 2026 was Capital Research Global Investors, an estimated $725M sold.

Based on aggregated 13F filings for Q2 2026.