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Vertex Pharmaceuticals

1,747 hedge funds and large institutions have $119B invested in Vertex Pharmaceuticals in 2026 Q2 according to their latest regulatory filings, with 191 funds opening new positions, 704 increasing their positions, 616 reducing their positions, and 109 closing their positions.

New
Increased
Maintained
Reduced
Closed

75% more first-time investments, than exits

New positions opened: 191 | Existing positions closed: 109

14% more repeat investments, than reductions

Existing positions increased: 704 | Existing positions reduced: 616

13% more capital invested

Capital invested by funds: $106B → $119B (+$13.4B)

3% more funds holding

Funds holding: 1,6951,747 (+52)

1.38% more ownership

Funds ownership: 93.56%94.94% (+1.4%)

9% more call options, than puts

Call options by funds: $853M | Put options by funds: $783M

29% less funds holding in top 10

Funds holding in top 10: 1712 (-5)

Holders
1,747
Holders Change
+52
Holders Change %
+3.07%
% of All Funds
21.1%
Holding in Top 10
12
Holding in Top 10 Change
-5
Holding in Top 10 Change %
-29.41%
% of All Funds
0.14%
New
191
Increased
704
Reduced
616
Closed
109
Calls
$853M
Puts
$783M
Net Calls
+$69.7M
Net Calls Change
-$97.3M
Name Holding Trade Value Shares
Change
Change in
Stake
UF
501
Univest Financial
Pennsylvania
$4.49M +$880K +1,986 +28%
CCM
502
Canal Capital Management
Virginia
$4.49M +$4.01M +9,045 New
AS
503
Aware Super
Australia
$4.49M +$4.01M +9,038 New
EWA
504
EP Wealth Advisors
California
$4.48M +$173K +390 +5%
SGH
505
Sivik Global Healthcare
Connecticut
$4.46M
EF
506
Empirical Finance
Pennsylvania
$4.46M +$129K +292 +3%
MC
507
Machina Capital
France
$4.45M -$305K -688 -7%
PWM
508
Perigon Wealth Management
California
$4.39M +$1.05M +2,380 +37%
EOJOAM
509
E. Ohman J:or Asset Management
Sweden
$4.38M
BBHC
510
Brown Brothers Harriman & Co
New York
$4.36M +$1.31M +2,947 +50%
SCM
511
Sterling Capital Management
North Carolina
$4.3M -$2.08M -4,690 -35%
SC
512
Sepio Capital
Utah
$4.28M +$146K +329 +4%
MK
513
MASTERINVEST Kapitalanlage
$4.23M +$100K +226 +3%
B
514
Bensler
Washington
$4.23M +$111K +250 +3%
NME
515
Notis-McConarty Edward
$4.18M +$238K +538 +7%
RFN
516
RDA Financial Network
Iowa
$4.18M +$548K +1,236 +17%
CP
517
Cumberland Partners
Ontario, Canada
$4.16M -$447K -1,008 -11%
QIM
518
Quantitative Investment Management
Virginia
$4.14M +$3.7M +8,342 New
NED
519
Nancy E. Dempze
$4.11M +$209K +472 +6%
YIH
520
Y-Intercept (HK)
Hong Kong
$4.11M -$12.2M -27,548 -77%
MWM
521
Mission Wealth Management
California
$4.06M +$1.81M +4,075 +100%
NMIMC
522
Northwestern Mutual Investment Management Company
Wisconsin
$4.04M +$4.43K +10 +0.1%
HCM
523
Howard Capital Management
Georgia
$4.03M +$1.84M +4,143 +104%
LTAS
524
Linden Thomas Advisory Services
North Carolina
$4.03M -$8.86K -20 -0.2%
Envestnet Portfolio Solutions
525
Envestnet Portfolio Solutions
Illinois
$4.01M -$281K -633 -7%

VRTX Hedge Fund Activity: Q2 2026 in Review

1,747 of the 8,279 institutional investors tracked by Wall St. Rank reported a position in Vertex Pharmaceuticals (VRTX) for Q2 2026, worth a combined $119B — up 13% from $106B a quarter earlier.

Buyers outnumbered sellers: 191 funds opened new VRTX positions and 109 closed out — a net gain of 82 holders — while 704 added to existing stakes and 616 trimmed.

The largest buyer was Franklin Resources, adding an estimated $1.24B. The largest seller was Capital Research Global Investors, cutting an estimated $725M.

  • 1,747 institutional investors held Vertex Pharmaceuticals (VRTX) as of Q2 2026, up from 1,695 in Q1 2026.
  • Funds reported $119B of Vertex Pharmaceuticals stock for Q2 2026, up 13% quarter-over-quarter.
  • 191 funds opened new Vertex Pharmaceuticals positions in Q2 2026 and 109 closed out, a net change of +82 holders.
  • The largest Vertex Pharmaceuticals buyer in Q2 2026 was Franklin Resources, an estimated $1.24B added.
  • The largest Vertex Pharmaceuticals seller in Q2 2026 was Capital Research Global Investors, an estimated $725M sold.

Based on aggregated 13F filings for Q2 2026.