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Vertex Pharmaceuticals

1,747 hedge funds and large institutions have $119B invested in Vertex Pharmaceuticals in 2026 Q2 according to their latest regulatory filings, with 191 funds opening new positions, 704 increasing their positions, 616 reducing their positions, and 109 closing their positions.

New
Increased
Maintained
Reduced
Closed

75% more first-time investments, than exits

New positions opened: 191 | Existing positions closed: 109

14% more repeat investments, than reductions

Existing positions increased: 704 | Existing positions reduced: 616

13% more capital invested

Capital invested by funds: $106B → $119B (+$13.4B)

3% more funds holding

Funds holding: 1,6951,747 (+52)

1.38% more ownership

Funds ownership: 93.56%94.94% (+1.4%)

9% more call options, than puts

Call options by funds: $853M | Put options by funds: $783M

29% less funds holding in top 10

Funds holding in top 10: 1712 (-5)

Holders
1,747
Holders Change
+52
Holders Change %
+3.07%
% of All Funds
21.1%
Holding in Top 10
12
Holding in Top 10 Change
-5
Holding in Top 10 Change %
-29.41%
% of All Funds
0.14%
New
191
Increased
704
Reduced
616
Closed
109
Calls
$853M
Puts
$783M
Net Calls
+$69.7M
Net Calls Change
-$97.3M
Name Holding Trade Value Shares
Change
Change in
Stake
Legal & General Group
26
Legal & General Group
United Kingdom
$929M -$38M -85,749 -4%
T. Rowe Price Associates
27
T. Rowe Price Associates
Maryland
$859M -$14M -31,701 -2%
Bank of New York Mellon
28
Bank of New York Mellon
New York
$831M +$38.2M +86,196 +5%
Deutsche Bank
29
Deutsche Bank
Germany
$784M +$18.3M +41,374 +3%
Amundi
30
Amundi
France
$768M +$32.8M +74,013 +5%
Fidelity Investments
31
Fidelity Investments
Massachusetts
$724M -$250M -563,107 -28%
Vanguard Fiduciary Trust
32
Vanguard Fiduciary Trust
Pennsylvania
$708M -$17.9M -40,334 -3%
JT
33
Jupiter Topco
New York
$626M +$558M +1,259,997 New
Dimensional Fund Advisors
34
Dimensional Fund Advisors
Texas
$581M +$79.6M +179,614 +18%
WCM Investment Management
35
WCM Investment Management
California
$576M +$13.6M +30,753 +3%
Nuveen
36
Nuveen
North Carolina
$537M -$1.25M -2,810 -0.3%
Royal Bank of Canada
37
Royal Bank of Canada
Ontario, Canada
$487M -$58.3M -131,612 -12%
BNP Paribas Asset Management
38
BNP Paribas Asset Management
France
$446M +$22.1M +49,846 +6%
Assenagon Asset Management
39
Assenagon Asset Management
Luxembourg
$377M +$98.5M +222,316 +41%
Wells Fargo
40
Wells Fargo
California
$372M +$2.01M +4,533 +0.6%
Arrowstreet Capital
41
Arrowstreet Capital
Massachusetts
$367M +$44.1M +99,428 +16%
Barclays
42
Barclays
United Kingdom
$364M +$31M +70,011 +11%
Swiss National Bank
43
Swiss National Bank
Switzerland
$356M -$12M -27,160 -4%
UBS Group
44
UBS Group
Switzerland
$354M +$36.2M +81,641 +13%
Citigroup
45
Citigroup
New York
$351M +$10.7M +24,161 +4%
HSBC Holdings
46
HSBC Holdings
United Kingdom
$336M +$9.22M +20,804 +3%
Mitsubishi UFJ Asset Management
47
Mitsubishi UFJ Asset Management
Japan
$321M +$22M +49,696 +8%
AQR Capital Management
48
AQR Capital Management
Connecticut
$305M +$197M +445,139 +260%
Sumitomo Mitsui Trust Group
49
Sumitomo Mitsui Trust Group
Japan
$304M -$1.13M -2,541 -0.4%
American Century Companies
50
American Century Companies
Missouri
$289M -$103M -232,384 -29%

VRTX Hedge Fund Activity: Q2 2026 in Review

1,747 of the 8,279 institutional investors tracked by Wall St. Rank reported a position in Vertex Pharmaceuticals (VRTX) for Q2 2026, worth a combined $119B — up 13% from $106B a quarter earlier.

Buyers outnumbered sellers: 191 funds opened new VRTX positions and 109 closed out — a net gain of 82 holders — while 704 added to existing stakes and 616 trimmed.

The largest buyer was Franklin Resources, adding an estimated $1.24B. The largest seller was Capital Research Global Investors, cutting an estimated $725M.

  • 1,747 institutional investors held Vertex Pharmaceuticals (VRTX) as of Q2 2026, up from 1,695 in Q1 2026.
  • Funds reported $119B of Vertex Pharmaceuticals stock for Q2 2026, up 13% quarter-over-quarter.
  • 191 funds opened new Vertex Pharmaceuticals positions in Q2 2026 and 109 closed out, a net change of +82 holders.
  • The largest Vertex Pharmaceuticals buyer in Q2 2026 was Franklin Resources, an estimated $1.24B added.
  • The largest Vertex Pharmaceuticals seller in Q2 2026 was Capital Research Global Investors, an estimated $725M sold.

Based on aggregated 13F filings for Q2 2026.