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Vertex Pharmaceuticals

1,747 hedge funds and large institutions have $119B invested in Vertex Pharmaceuticals in 2026 Q2 according to their latest regulatory filings, with 191 funds opening new positions, 704 increasing their positions, 616 reducing their positions, and 109 closing their positions.

New
Increased
Maintained
Reduced
Closed

75% more first-time investments, than exits

New positions opened: 191 | Existing positions closed: 109

14% more repeat investments, than reductions

Existing positions increased: 704 | Existing positions reduced: 616

13% more capital invested

Capital invested by funds: $106B → $119B (+$13.4B)

3% more funds holding

Funds holding: 1,6951,747 (+52)

1.38% more ownership

Funds ownership: 93.56%94.94% (+1.4%)

9% more call options, than puts

Call options by funds: $853M | Put options by funds: $783M

29% less funds holding in top 10

Funds holding in top 10: 1712 (-5)

Holders
1,747
Holders Change
+52
Holders Change %
+3.07%
% of All Funds
21.1%
Holding in Top 10
12
Holding in Top 10 Change
-5
Holding in Top 10 Change %
-29.41%
% of All Funds
0.14%
New
191
Increased
704
Reduced
616
Closed
109
Calls
$853M
Puts
$783M
Net Calls
+$69.7M
Net Calls Change
-$97.3M
Name Holding Trade Value Shares
Change
Change in
Stake
BBA
451
Baader Bank Aktiengesellschaft
Germany
$5.85M +$2.88M +6,497 +123%
DRD
452
Dennis R. Delaney
$5.83M +$37.2K +84 +0.7%
LNWTC
453
Laird Norton Wetherby Trust Company
Washington
$5.73M -$160K -362 -3%
DA
454
DCF Advisers
Connecticut
$5.71M +$1.99M +4,500 +64%
HR
455
Howe & Rusling
New York
$5.71M +$788K +1,778 +18%
EFM
456
E Fund Management
China
$5.69M +$283K +639 +6%
ALMGDA
457
AG2R La Mondiale Gestion d'Actifs
France
$5.62M +$418K +943 +9%
NW
458
NewEdge Wealth
Pennsylvania
$5.62M +$672K +1,517 +15%
Jane Street
459
Jane Street
New York
$5.58M -$49.5M -111,715 -91%
FHC
460
First Horizon Corporation
Tennessee
$5.56M -$1.48M -3,334 -23%
JHC
461
Jones Hill Capital
New York
$5.53M -$43.2M -97,480 -90%
HWM
462
HB Wealth Management
Georgia
$5.5M +$345K +778 +8%
PIMJS
463
PKO Investment Management Joint-Stock
Poland
$5.49M +$22.2K +50 +0.5%
BEI
464
Benjamin Edwards Inc
Missouri
$5.48M -$40.8K -92 -0.8%
MGP
465
Metis Global Partners
California
$5.43M -$327K -738 -6%
NAAA
466
New Age Alpha Advisors
New York
$5.43M -$218K -491 -4%
BA
467
Bridgewater Associates
Connecticut
$5.4M -$1.1M -2,492 -19%
JGCM
468
Joseph Group Capital Management
Ohio
$5.34M +$107K +242 +2%
NB
469
Northwest Bancshares
Pennsylvania
$5.32M +$128K +288 +3%
GIC
470
Generali Investments CEE
Czech Republic
$5.26M
KPWS
471
Kestra Private Wealth Services
Texas
$5.24M +$383K +864 +9%
MAM
472
Morse Asset Management
Connecticut
$5.23M -$17.3K -39 -0.4%
SAM
473
Simplify Asset Management
Nevada
$5.19M +$1.12M +2,520 +32%
Bessemer Group
474
Bessemer Group
New Jersey
$5.17M +$817K +1,843 +22%
GH
475
GAM Holding
Switzerland
$5.15M +$2.13M +4,796 +86%

VRTX Hedge Fund Activity: Q2 2026 in Review

1,747 of the 8,279 institutional investors tracked by Wall St. Rank reported a position in Vertex Pharmaceuticals (VRTX) for Q2 2026, worth a combined $119B — up 13% from $106B a quarter earlier.

Buyers outnumbered sellers: 191 funds opened new VRTX positions and 109 closed out — a net gain of 82 holders — while 704 added to existing stakes and 616 trimmed.

The largest buyer was Franklin Resources, adding an estimated $1.24B. The largest seller was Capital Research Global Investors, cutting an estimated $725M.

  • 1,747 institutional investors held Vertex Pharmaceuticals (VRTX) as of Q2 2026, up from 1,695 in Q1 2026.
  • Funds reported $119B of Vertex Pharmaceuticals stock for Q2 2026, up 13% quarter-over-quarter.
  • 191 funds opened new Vertex Pharmaceuticals positions in Q2 2026 and 109 closed out, a net change of +82 holders.
  • The largest Vertex Pharmaceuticals buyer in Q2 2026 was Franklin Resources, an estimated $1.24B added.
  • The largest Vertex Pharmaceuticals seller in Q2 2026 was Capital Research Global Investors, an estimated $725M sold.

Based on aggregated 13F filings for Q2 2026.