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Vertex Pharmaceuticals

1,747 hedge funds and large institutions have $119B invested in Vertex Pharmaceuticals in 2026 Q2 according to their latest regulatory filings, with 191 funds opening new positions, 704 increasing their positions, 616 reducing their positions, and 109 closing their positions.

New
Increased
Maintained
Reduced
Closed

75% more first-time investments, than exits

New positions opened: 191 | Existing positions closed: 109

14% more repeat investments, than reductions

Existing positions increased: 704 | Existing positions reduced: 616

13% more capital invested

Capital invested by funds: $106B → $119B (+$13.4B)

3% more funds holding

Funds holding: 1,6951,747 (+52)

1.38% more ownership

Funds ownership: 93.56%94.94% (+1.4%)

9% more call options, than puts

Call options by funds: $853M | Put options by funds: $783M

29% less funds holding in top 10

Funds holding in top 10: 1712 (-5)

Holders
1,747
Holders Change
+52
Holders Change %
+3.07%
% of All Funds
21.1%
Holding in Top 10
12
Holding in Top 10 Change
-5
Holding in Top 10 Change %
-29.41%
% of All Funds
0.14%
New
191
Increased
704
Reduced
616
Closed
109
Calls
$853M
Puts
$783M
Net Calls
+$69.7M
Net Calls Change
-$97.3M
Name Holding Trade Value Shares
Change
Change in
Stake
NYLIM
251
New York Life Investment Management
New York
$21.5M +$2.28M +5,149 +14%
Vanguard Personalized Indexing Management
252
Vanguard Personalized Indexing Management
California
$21.4M +$677K +1,528 +4%
MAM
253
Martingale Asset Management
Massachusetts
$21.2M -$896K -2,021 -5%
Federated Hermes
254
Federated Hermes
Pennsylvania
$21.2M -$12.9M -29,159 -41%
Acadian Asset Management
255
Acadian Asset Management
Massachusetts
$20.9M +$7.2M +16,254 +63%
OSAM
256
O'Shaughnessy Asset Management
Connecticut
$20.9M -$8.78M -19,804 -32%
Wealthfront Advisers
257
Wealthfront Advisers
California
$20.7M -$2.12M -4,787 -10%
Public Sector Pension Investment Board (PSP Investments)
258
Public Sector Pension Investment Board (PSP Investments)
Quebec, Canada
$20.5M +$69.6K +157 +0.4%
VMPIC
259
Varma Mutual Pension Insurance Co
Finland
$20.3M -$1.24M -2,800 -6%
HF
260
HRT Financial
New York
$20.1M +$6.09M +13,743 +51%
TBC
261
Tweedy, Browne Co
Connecticut
$19.9M -$118K -266 -0.7%
FLPIM
262
F.L. Putnam Investment Management
Massachusetts
$19.9M +$274K +618 +2%
IHAM
263
Integral Health Asset Management
New York
$19.9M
SA
264
Sanctuary Advisors
Indiana
$19.8M -$4.23M -9,549 -19%
BBVA
265
Banco Bilbao Vizcaya Argentaria
Spain
$19.7M -$429K -969 -2%
AP
266
Americana Partners
Texas
$19.3M +$4.05M +9,141 +31%
MML Investors Services
267
MML Investors Services
Massachusetts
$19.3M +$2.43M +5,488 +16%
FISPB
268
Fideuram - Intesa Sanpaolo Private Banking
$19.2M +$1.67M +3,761 +11%
URS
269
Utah Retirement Systems
Utah
$19.2M -$1.18M -2,663 -6%
NLGIA
270
Nippon Life Global Investors Americas
New York
$19M +$15.8M +35,730 +1,429%
BCIM
271
British Columbia Investment Management
British Columbia, Canada
$18.9M +$1.41M +3,173 +9%
PFSRSONJ
272
Police & Firemen's Retirement System of New Jersey
New Jersey
$18.9M -$478K -1,079 -3%
Macquarie Group
273
Macquarie Group
Australia
$18.9M -$1,000K -2,256 -6%
AAP
274
Aristotle Atlantic Partners
Florida
$18.6M -$19.1K -43 -0.1%
IC
275
IEQ Capital
California
$18.5M +$4.5M +10,164 +37%

VRTX Hedge Fund Activity: Q2 2026 in Review

1,747 of the 8,279 institutional investors tracked by Wall St. Rank reported a position in Vertex Pharmaceuticals (VRTX) for Q2 2026, worth a combined $119B — up 13% from $106B a quarter earlier.

Buyers outnumbered sellers: 191 funds opened new VRTX positions and 109 closed out — a net gain of 82 holders — while 704 added to existing stakes and 616 trimmed.

The largest buyer was Franklin Resources, adding an estimated $1.24B. The largest seller was Capital Research Global Investors, cutting an estimated $725M.

  • 1,747 institutional investors held Vertex Pharmaceuticals (VRTX) as of Q2 2026, up from 1,695 in Q1 2026.
  • Funds reported $119B of Vertex Pharmaceuticals stock for Q2 2026, up 13% quarter-over-quarter.
  • 191 funds opened new Vertex Pharmaceuticals positions in Q2 2026 and 109 closed out, a net change of +82 holders.
  • The largest Vertex Pharmaceuticals buyer in Q2 2026 was Franklin Resources, an estimated $1.24B added.
  • The largest Vertex Pharmaceuticals seller in Q2 2026 was Capital Research Global Investors, an estimated $725M sold.

Based on aggregated 13F filings for Q2 2026.