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Vertex Pharmaceuticals

1,747 hedge funds and large institutions have $119B invested in Vertex Pharmaceuticals in 2026 Q2 according to their latest regulatory filings, with 191 funds opening new positions, 704 increasing their positions, 616 reducing their positions, and 109 closing their positions.

New
Increased
Maintained
Reduced
Closed

75% more first-time investments, than exits

New positions opened: 191 | Existing positions closed: 109

14% more repeat investments, than reductions

Existing positions increased: 704 | Existing positions reduced: 616

13% more capital invested

Capital invested by funds: $106B → $119B (+$13.4B)

3% more funds holding

Funds holding: 1,6951,747 (+52)

1.38% more ownership

Funds ownership: 93.56%94.94% (+1.4%)

9% more call options, than puts

Call options by funds: $853M | Put options by funds: $783M

29% less funds holding in top 10

Funds holding in top 10: 1712 (-5)

Holders
1,747
Holders Change
+52
Holders Change %
+3.07%
% of All Funds
21.1%
Holding in Top 10
12
Holding in Top 10 Change
-5
Holding in Top 10 Change %
-29.41%
% of All Funds
0.14%
New
191
Increased
704
Reduced
616
Closed
109
Calls
$853M
Puts
$783M
Net Calls
+$69.7M
Net Calls Change
-$97.3M
Name Holding Trade Value Shares
Change
Change in
Stake
P
226
PensionDanmark
Denmark
$26.9M +$2.17M +4,890 +10%
BIAS
227
Beacon Investment Advisory Services
New Jersey
$26.5M -$1.21M -2,724 -5%
Retirement Systems of Alabama
228
Retirement Systems of Alabama
Alabama
$26.5M -$274K -619 -1%
CA
229
Cullinan Associates
Kentucky
$25.7M
VWM
230
Valley Wealth Managers
New Jersey
$25.5M +$527K +1,190 +2%
CFG
231
Citizens Financial Group
Rhode Island
$25.3M +$516K +1,164 +2%
PI
232
PineBridge Investments
New York
$25.2M -$1.9M -4,281 -8%
Commonwealth Equity Services
233
Commonwealth Equity Services
Massachusetts
$25.2M -$1.84M -4,159 -8%
EF
234
Empowered Funds
Pennsylvania
$24.9M +$3.75M +8,460 +20%
Osaic Holdings
235
Osaic Holdings
Arizona
$24.6M +$2.49M +5,614 +13%
HighTower Advisors
236
HighTower Advisors
Illinois
$24.3M -$7.39M -16,664 -25%
UIM
237
USS Investment Management
United Kingdom
$24.3M +$782K +1,765 +4%
DIA
238
Davidson Investment Advisors
Montana
$24.2M -$1.11M -2,512 -5%
CUAMC
239
China Universal Asset Management Company
China
$24M +$1.93M +4,363 +10%
AB
240
Amalgamated Bank
New York
$23.7M -$2.46M -5,553 -10%
ADEF
241
Adams Diversified Equity Fund
Maryland
$23.5M +$21M +47,300 New
QC
242
Quadrature Capital
United Kingdom
$23.3M +$20.8M +46,945 New
CWG
243
C WorldWide Group
Denmark
$22.9M
Pathstone Holdings
244
Pathstone Holdings
New Jersey
$22.9M +$749K +1,690 +4%
X
245
Xponance
Pennsylvania
$22.8M -$11M -24,734 -35%
O
246
Ossiam
France
$22.8M +$2.89M +6,522 +17%
Lido Advisors
247
Lido Advisors
California
$22.5M +$814K +1,836 +4%
WC
248
Whitney & Co
New York
$22.2M +$265K +597 +1%
ZIG
249
Zurich Insurance Group
Switzerland
$21.7M -$456K -1,029 -2%
Wealth Enhancement Advisory Services
250
Wealth Enhancement Advisory Services
Minnesota
$21.5M +$2.31M +5,221 +13%

VRTX Hedge Fund Activity: Q2 2026 in Review

1,747 of the 8,279 institutional investors tracked by Wall St. Rank reported a position in Vertex Pharmaceuticals (VRTX) for Q2 2026, worth a combined $119B — up 13% from $106B a quarter earlier.

Buyers outnumbered sellers: 191 funds opened new VRTX positions and 109 closed out — a net gain of 82 holders — while 704 added to existing stakes and 616 trimmed.

The largest buyer was Franklin Resources, adding an estimated $1.24B. The largest seller was Capital Research Global Investors, cutting an estimated $725M.

  • 1,747 institutional investors held Vertex Pharmaceuticals (VRTX) as of Q2 2026, up from 1,695 in Q1 2026.
  • Funds reported $119B of Vertex Pharmaceuticals stock for Q2 2026, up 13% quarter-over-quarter.
  • 191 funds opened new Vertex Pharmaceuticals positions in Q2 2026 and 109 closed out, a net change of +82 holders.
  • The largest Vertex Pharmaceuticals buyer in Q2 2026 was Franklin Resources, an estimated $1.24B added.
  • The largest Vertex Pharmaceuticals seller in Q2 2026 was Capital Research Global Investors, an estimated $725M sold.

Based on aggregated 13F filings for Q2 2026.