|
1
|
Avoro Capital Advisors
New York
|
$190M
|
–
|
–
|
–
|
|
|
2
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$174M
|
+$12.1M
|
+318,974
|
+9%
|
|
|
3
|
|
$153M
|
+$4.35M
|
+114,530
|
+3%
|
|
|
4
|
Sofinnova Investments
Menlo Park,
California
|
$123M
|
–
|
–
|
–
|
|
|
5
|
Fidelity Investments
Boston,
Massachusetts
|
$123M
|
-$632K
|
-16,654
|
-0.6%
|
|
|
6
|
Vanguard Group
Malvern,
Pennsylvania
|
$114M
|
+$2.13M
|
+56,001
|
+2%
|
|
|
7
|
Commodore Capital
New York
|
$109M
|
–
|
–
|
–
|
|
|
8
|
Eversept Partners
New York
|
$90.6M
|
+$263K
|
+6,943
|
+0.3%
|
|
|
9
|
Holocene Advisors
New York
|
$86.4M
|
+$6.01M
|
+158,451
|
+9%
|
|
|
10
|
State Street
Boston,
Massachusetts
|
$80.6M
|
-$12.6M
|
-331,746
|
-15%
|
|
|
11
|
Kynam Capital Management
Princeton,
New Jersey
|
$69.7M
|
+$1.25M
|
+32,880
|
+2%
|
|
|
12
|
Adage Capital Partners
Boston,
Massachusetts
|
$60.7M
|
+$9.68M
|
+255,000
|
+23%
|
|
|
13
|
|
$60.1M
|
+$4.83M
|
+127,316
|
+10%
|
|
|
14
|
Paradigm Biocapital Advisors
New York
|
$48.5M
|
+$41.6M
|
+1,096,851
|
New
|
|
|
15
|
Geode Capital Management
Boston,
Massachusetts
|
$44.4M
|
+$767K
|
+20,223
|
+2%
|
|
|
16
|
Woodline Partners
San Francisco,
California
|
$44.2M
|
+$1.97M
|
+51,976
|
+5%
|
|
|
17
|
T. Rowe Price Investment Management
Baltimore,
Maryland
|
$43.5M
|
+$37.3M
|
+984,001
|
New
|
|
|
18
|
Siren LLC
Greenwich,
Connecticut
|
$37M
|
+$31.8M
|
+837,928
|
New
|
|
|
19
|
Deutsche Bank
Frankfurt Am Main Ge,
Germany
|
$33.9M
|
+$4.98M
|
+131,184
|
+21%
|
|
|
20
|
First Light Asset Management
Edina,
Minnesota
|
$31.2M
|
-$11.4M
|
-300,489
|
-30%
|
|
|
21
|
Altium Capital Management
New York
|
$30.2M
|
-$1.14M
|
-30,000
|
-4%
|
|
|
22
|
|
$29.9M
|
–
|
–
|
–
|
|
|
23
|
|
$26.5M
|
-$7.01M
|
-184,714
|
-24%
|
|
|
24
|
Marshall Wace
London,
United Kingdom
|
$25.8M
|
+$2.24M
|
+59,147
|
+11%
|
|
|
25
|
Pictet Asset Management
Carouge,
Switzerland
|
$25.3M
|
-$1.96M
|
-51,651
|
-8%
|
|
