|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$94.2M
|
+$18.7M
|
+866,828
|
+28%
|
|
|
2
|
Sofinnova Investments
Menlo Park,
California
|
$74.7M
|
+$5.74M
|
+266,666
|
+9%
|
|
|
3
|
Abingworth
London,
United Kingdom
|
$69.3M
|
–
|
–
|
–
|
|
|
4
|
Citadel Advisors
Miami,
Florida
|
$49.1M
|
+$7.67M
|
+356,338
|
+21%
|
|
|
5
|
RA Capital Management
Boston,
Massachusetts
|
$46.2M
|
+$42.3M
|
+1,966,084
|
New
|
|
|
6
|
|
$16M
|
+$4.83M
|
+224,575
|
+49%
|
|
|
7
|
Vivo Capital
Palo Alto,
California
|
$15.7M
|
+$14.3M
|
+666,666
|
New
|
|
|
8
|
Vanguard Group
Malvern,
Pennsylvania
|
$14.5M
|
+$4.93M
|
+229,025
|
+59%
|
|
|
9
|
Octagon Capital Advisors
New York
|
$13.5M
|
-$2.06M
|
-95,940
|
-14%
|
|
|
10
|
Kynam Capital Management
Princeton,
New Jersey
|
$11.8M
|
+$5.35M
|
+248,879
|
+98%
|
|
|
11
|
International Biotechnology Trust
London,
United Kingdom
|
$11.6M
|
+$1.51M
|
+70,214
|
+58%
|
|
|
12
|
Logos Global Management
San Francisco,
California
|
$9.04M
|
+$7.21M
|
+335,000
|
+670%
|
|
|
13
|
Baker Bros. Advisors
New York
|
$7.83M
|
+$7.17M
|
+333,333
|
New
|
|
|
14
|
Alphabet Inc
Mountain View,
California
|
$7.08M
|
-$8.87M
|
-412,078
|
-58%
|
|
|
15
|
Geode Capital Management
Boston,
Massachusetts
|
$4.76M
|
+$1.74M
|
+80,965
|
+67%
|
|
|
16
|
State Street
Boston,
Massachusetts
|
$3.96M
|
+$979K
|
+45,484
|
+37%
|
|
|
17
|
|
$3.51M
|
+$1.58M
|
+73,475
|
+97%
|
|
|
18
|
Millennium Management
New York
|
$3.14M
|
+$2.87M
|
+133,500
|
New
|
|
|
19
|
Northern Trust
Chicago,
Illinois
|
$2.57M
|
+$679K
|
+31,554
|
+41%
|
|
|
20
|
Maven Securities
St Helier,
Jersey
|
$1.51M
|
+$1.38M
|
+64,240
|
New
|
|
|
21
|
Polar Asset Management Partners
Toronto,
Ontario, Canada
|
$1.41M
|
+$1.29M
|
+60,000
|
New
|
|
|
22
|
Bank of New York Mellon
New York
|
$1.15M
|
+$608K
|
+28,247
|
+137%
|
|
|
23
|
Nuveen
Charlotte,
North Carolina
|
$1.14M
|
+$829K
|
+38,525
|
+255%
|
|
|
24
|
Charles Schwab
San Francisco,
California
|
$817K
|
+$242K
|
+11,251
|
+48%
|
|
|
25
|
|
$435K
|
-$176K
|
-8,173
|
-31%
|
|
