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Trevi Therapeutics

164 hedge funds and large institutions have $1.18B invested in Trevi Therapeutics in 2025 Q3 according to their latest regulatory filings, with 35 funds opening new positions, 65 increasing their positions, 42 reducing their positions, and 23 closing their positions.

New
Increased
Maintained
Reduced
Closed

89% more capital invested

Capital invested by funds: $627M → $1.18B (+$556M)

55% more repeat investments, than reductions

Existing positions increased: 65 | Existing positions reduced: 42

52% more first-time investments, than exits

New positions opened: 35 | Existing positions closed: 23

8.45% more ownership

Funds ownership: 97.75%106.2% (+8.4%)

7% more funds holding

Funds holding: 153164 (+11)

14% less funds holding in top 10

Funds holding in top 10: 76 (-1)

48% less call options, than puts

Call options by funds: $8.43M | Put options by funds: $16.3M

Holders
164
Holders Change
+11
Holders Change %
+7.19%
% of All Funds
2.15%
Holding in Top 10
6
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-14.29%
% of All Funds
0.08%
New
35
Increased
65
Reduced
42
Closed
23
Calls
$8.43M
Puts
$16.3M
Net Calls
-$7.85M
Net Calls Change
-$11.9M
Name Holding Trade Value Shares
Change
Change in
Stake
NMC
1
NEA Management Company
Maryland
$121M
FLSM
2
Frazier Life Sciences Management
California
$93.9M
BlackRock
3
BlackRock
New York
$90.6M +$12.7M +1,696,047 +21%
RCMNY
4
Rubric Capital Management (New York)
New York
$78.1M
Vanguard Group
5
Vanguard Group
Pennsylvania
$53.3M +$3.83M +510,295 +10%
Viking Global Investors
6
Viking Global Investors
Connecticut
$46.9M +$26.9M +3,585,875 +232%
VC
7
Vivo Capital
California
$46.6M +$4.55M +606,765 +14%
Marshall Wace
8
Marshall Wace
United Kingdom
$44.3M +$17.7M +2,363,835 +95%
Morgan Stanley
9
Morgan Stanley
New York
$39.4M +$24.6M +3,277,715 +320%
AllianceBernstein
10
AllianceBernstein
Tennessee
$39.3M +$83.2K +11,096 +0.3%
MB
11
MPM BioImpact
Massachusetts
$31.2M
O
12
OrbiMed
New York
$30.3M
Fidelity Investments
13
Fidelity Investments
Massachusetts
$30.2M +$22M +2,931,362 +795%
Wellington Management Group
14
Wellington Management Group
Massachusetts
$29.8M +$23.1M +3,081,906 +1,792%
OCA
15
Octagon Capital Advisors
New York
$25.8M -$6.43M -857,000 -23%
AAA
16
Affinity Asset Advisors
New York
$25.6M +$1.99M +265,942 +10%
SL
17
Siren LLC
Connecticut
$23.2M -$10.5M -1,401,926 -36%
Geode Capital Management
18
Geode Capital Management
Massachusetts
$20.3M +$3.25M +434,081 +24%
State Street
19
State Street
Massachusetts
$20.3M +$2.9M +386,502 +21%
LGM
20
Logos Global Management
California
$20.1M +$10.1M +1,350,000 +159%
ACA
21
Acorn Capital Advisors
New York
$19.6M
AGP
22
Artia Global Partners
Florida
$18.3M +$5.16M +687,862 +52%
Bank of America
23
Bank of America
North Carolina
$16.8M +$5.54M +739,342 +67%
Susquehanna International Group
24
Susquehanna International Group
Pennsylvania
$14.6M +$11M +1,473,157 +1,155%
Raymond James Financial
25
Raymond James Financial
Florida
$12.9M +$2.51M +334,354 +31%

TRVI Hedge Fund Activity: Q3 2025 in Review

164 of the 7,620 institutional investors tracked by Wall St. Rank reported a position in Trevi Therapeutics (TRVI) for Q3 2025, worth a combined $1.18B — up 89% from $627M a quarter earlier.

Buyers outnumbered sellers: 35 funds opened new TRVI positions and 23 closed out — a net gain of 12 holders — while 65 added to existing stakes and 42 trimmed.

The largest buyer was Viking Global Investors, adding an estimated $26.9M. The largest seller was Woodline Partners, cutting an estimated $29.6M.

  • 164 institutional investors held Trevi Therapeutics (TRVI) as of Q3 2025, up from 153 in Q2 2025.
  • Funds reported $1.18B of Trevi Therapeutics stock for Q3 2025, up 89% quarter-over-quarter.
  • 35 funds opened new Trevi Therapeutics positions in Q3 2025 and 23 closed out, a net change of +12 holders.
  • The largest Trevi Therapeutics buyer in Q3 2025 was Viking Global Investors, an estimated $26.9M added.
  • The largest Trevi Therapeutics seller in Q3 2025 was Woodline Partners, an estimated $29.6M sold.

Based on aggregated 13F filings for Q3 2025.