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Trevi Therapeutics
TRVI

Overview Fund Activity

137 hedge funds and large institutions have $554M invested in Trevi Therapeutics in 2025 Q1 according to their latest regulatory filings, with 42 funds opening new positions, 53 increasing their positions, 32 reducing their positions, and 14 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
137
Holders Change
+27
Holders Change %
+24.55%
% of All Funds
1.86%
Holding in Top 10
8
Holding in Top 10 Change
+7
Holding in Top 10 Change %
+700%
% of All Funds
0.11%
New
42
Increased
53
Reduced
32
Closed
14
Calls
$10.7M
Puts
$2.23M
Net Calls
+$8.5M
Net Calls Change
+$8.64M

Top Buyers

1
OCA
Octagon Capital Advisors
New York
+$20.9M
2
AC
Armistice Capital
New York
+$18.8M
3
Marshall Wace
Marshall Wace
United Kingdom
+$15.8M
4
Balyasny Asset Management
Balyasny Asset Management
Illinois
+$11.1M
5
BlackRock
BlackRock
New York
+$8.71M

Top Sellers

1
Adage Capital Partners
Adage Capital Partners
Massachusetts
-$13M
2
Point72 Asset Management
Point72 Asset Management
Connecticut
-$11.2M
3
OM
Opaleye Management
Massachusetts
-$9.58M
4
Viking Global Investors
Viking Global Investors
Connecticut
-$7.37M
5
WP
Woodline Partners
California
-$7.26M
Name Holding Trade Value Shares
Change 		Shares
Change %
NMC
1
NEA Management Company
Maryland
$71.5M – – –
FLSM
2
Frazier Life Sciences Management
California
$64.5M -$2.55M -405,365 -4%
BlackRock
3
BlackRock
New York
$33.4M +$8.71M +1,384,080 +35%
RCMNY
4
Rubric Capital Management (New York)
New York
$28.5M +$2.1M +333,406 +8%
Vanguard Group
5
Vanguard Group
Pennsylvania
$24.1M +$2.07M +328,819 +9%
VC
6
Vivo Capital
California
$21.9M – – –
MB
7
MPM BioImpact
Massachusetts
$21.6M +$2.1M +333,470 +11%
OCA
8
Octagon Capital Advisors
New York
$20.9M +$20.9M +3,322,000 New
Viking Global Investors
9
Viking Global Investors
Connecticut
$20.3M -$7.37M -1,172,208 -27%
AC
10
Armistice Capital
New York
$18.8M +$18.8M +2,988,000 New
SL
11
Siren LLC
Connecticut
$18M -$266K -42,267 -1%
Marshall Wace
12
Marshall Wace
United Kingdom
$16.1M +$15.8M +2,511,300 +5,851%
Point72 Asset Management
13
Point72 Asset Management
Connecticut
$14.9M -$11.2M -1,782,232 -43%
ACA
14
Acorn Capital Advisors
New York
$13.5M +$904K +143,796 +7%
WP
15
Woodline Partners
California
$12.9M -$7.26M -1,154,785 -36%
Balyasny Asset Management
16
Balyasny Asset Management
Illinois
$11.1M +$11.1M +1,758,619 New
Geode Capital Management
17
Geode Capital Management
Massachusetts
$10.2M +$1.99M +315,543 +24%
State Street
18
State Street
Massachusetts
$8.96M +$1.6M +253,824 +22%
MCM
19
MAI Capital Management
Ohio
$8.71M +$177K +28,164 +2%
AAA
20
Affinity Asset Advisors
New York
$7.86M +$7.86M +1,250,000 New
O
21
OrbiMed
New York
$7.04M +$7.04M +1,120,000 New
Invesco
22
Invesco
Georgia
$5.37M +$5.22M +829,364 +3,511%
Millennium Management
23
Millennium Management
New York
$5.18M +$4.04M +642,830 +356%
OM
24
Opaleye Management
Massachusetts
$5M -$9.58M -1,522,500 -66%
ACP
25
Acuta Capital Partners
California
$4.94M +$88.1K +14,003 +2%
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