We are live on ! Find out more
TRVI icon

Trevi Therapeutics

153 hedge funds and large institutions have $627M invested in Trevi Therapeutics in 2025 Q2 according to their latest regulatory filings, with 39 funds opening new positions, 65 increasing their positions, 31 reducing their positions, and 23 closing their positions.

New
Increased
Maintained
Reduced
Closed

110% more repeat investments, than reductions

Existing positions increased: 65 | Existing positions reduced: 31

109% more call options, than puts

Call options by funds: $7.77M | Put options by funds: $3.73M

70% more first-time investments, than exits

New positions opened: 39 | Existing positions closed: 23

13% more capital invested

Capital invested by funds: $554M → $627M (+$72.8M)

12% more funds holding

Funds holding: 137153 (+16)

6.59% more ownership

Funds ownership: 91.16%97.75% (+6.6%)

13% less funds holding in top 10

Funds holding in top 10: 87 (-1)

Holders
153
Holders Change
+16
Holders Change %
+11.68%
% of All Funds
2.01%
Holding in Top 10
7
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-12.5%
% of All Funds
0.09%
New
39
Increased
65
Reduced
31
Closed
23
Calls
$7.77M
Puts
$3.73M
Net Calls
+$4.04M
Net Calls Change
-$4.46M
Name Holding Trade Value Shares
Change
Change in
Stake
NMC
1
NEA Management Company
Maryland
$72.3M +$11.5M +1,851,852 +16%
FLSM
2
Frazier Life Sciences Management
California
$56.1M
RCMNY
3
Rubric Capital Management (New York)
New York
$46.7M +$24.8M +3,993,325 +88%
BlackRock
4
BlackRock
New York
$44.9M +$18M +2,892,464 +54%
Vanguard Group
5
Vanguard Group
Pennsylvania
$29.1M +$9.2M +1,478,659 +39%
VC
6
Vivo Capital
California
$24.5M +$6.22M +1,000,000 +29%
AllianceBernstein
7
AllianceBernstein
Tennessee
$23.4M +$26.5M +4,259,015 +19,065%
WP
8
Woodline Partners
California
$22.1M +$12.4M +1,988,623 +97%
SL
9
Siren LLC
Connecticut
$21.5M +$6.69M +1,075,000 +38%
OCA
10
Octagon Capital Advisors
New York
$20.1M +$2.18M +350,000 +11%
MB
11
MPM BioImpact
Massachusetts
$18.6M -$133K -21,411 -0.6%
O
12
OrbiMed
New York
$18.1M +$13.6M +2,188,400 +195%
AAA
13
Affinity Asset Advisors
New York
$13.9M +$7.99M +1,284,058 +103%
Marshall Wace
14
Marshall Wace
United Kingdom
$13.6M -$475K -76,305 -3%
Balyasny Asset Management
15
Balyasny Asset Management
Illinois
$12.9M +$3.71M +595,783 +34%
ACA
16
Acorn Capital Advisors
New York
$11.7M
State Street
17
State Street
Massachusetts
$10M +$2.54M +408,414 +29%
Geode Capital Management
18
Geode Capital Management
Massachusetts
$9.78M +$1.07M +171,980 +11%
Point72 Asset Management
19
Point72 Asset Management
Connecticut
$9.46M -$3.98M -639,329 -27%
Viking Global Investors
20
Viking Global Investors
Connecticut
$8.44M -$10.5M -1,684,792 -52%
EAM
21
Eventide Asset Management
Massachusetts
$7.56M +$8.59M +1,381,324 New
Citadel Advisors
22
Citadel Advisors
Florida
$7.22M +$8.21M +1,319,266 New
AGP
23
Artia Global Partners
Florida
$7.18M +$8.16M +1,311,840 New
PBPIA
24
Pivotal bioVenture Partners Investment Advisor
California
$6.27M +$7.13M +1,146,110 New
Bank of America
25
Bank of America
North Carolina
$6M +$6.01M +965,732 +733%

TRVI Hedge Fund Activity: Q2 2025 in Review

153 of the 7,595 institutional investors tracked by Wall St. Rank reported a position in Trevi Therapeutics (TRVI) for Q2 2025, worth a combined $627M — up 13% from $554M a quarter earlier.

Buyers outnumbered sellers: 39 funds opened new TRVI positions and 23 closed out — a net gain of 16 holders — while 65 added to existing stakes and 31 trimmed.

The largest buyer was AllianceBernstein, adding an estimated $26.5M. The largest seller was Armistice Capital, exiting entirely with an estimated $18.8M sold.

  • 153 institutional investors held Trevi Therapeutics (TRVI) as of Q2 2025, up from 137 in Q1 2025.
  • Funds reported $627M of Trevi Therapeutics stock for Q2 2025, up 13% quarter-over-quarter.
  • 39 funds opened new Trevi Therapeutics positions in Q2 2025 and 23 closed out, a net change of +16 holders.
  • The largest Trevi Therapeutics buyer in Q2 2025 was AllianceBernstein, an estimated $26.5M added.
  • The largest Trevi Therapeutics seller in Q2 2025 was Armistice Capital, an estimated $18.8M sold.

Based on aggregated 13F filings for Q2 2025.