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Trevi Therapeutics

164 hedge funds and large institutions have $1.18B invested in Trevi Therapeutics in 2025 Q3 according to their latest regulatory filings, with 35 funds opening new positions, 65 increasing their positions, 42 reducing their positions, and 23 closing their positions.

New
Increased
Maintained
Reduced
Closed

89% more capital invested

Capital invested by funds: $627M → $1.18B (+$556M)

55% more repeat investments, than reductions

Existing positions increased: 65 | Existing positions reduced: 42

52% more first-time investments, than exits

New positions opened: 35 | Existing positions closed: 23

8.45% more ownership

Funds ownership: 97.75%106.2% (+8.4%)

7% more funds holding

Funds holding: 153164 (+11)

14% less funds holding in top 10

Funds holding in top 10: 76 (-1)

48% less call options, than puts

Call options by funds: $8.43M | Put options by funds: $16.3M

Holders
164
Holders Change
+11
Holders Change %
+7.19%
% of All Funds
2.15%
Holding in Top 10
6
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-14.29%
% of All Funds
0.08%
New
35
Increased
65
Reduced
42
Closed
23
Calls
$8.43M
Puts
$16.3M
Net Calls
-$7.85M
Net Calls Change
-$11.9M
Name Holding Trade Value Shares
Change
Change in
Stake
VCIM
51
Velan Capital Investment Management
Georgia
$1.88M +$1.54M +205,000 New
FAM
52
Fred Alger Management
New York
$1.75M +$987K +131,620 +221%
N
53
Nuveen
North Carolina
$1.68M +$104K +13,870 +8%
Royal Bank of Canada
54
Royal Bank of Canada
Ontario, Canada
$1.55M -$4.91M -655,186 -79%
Swiss National Bank
55
Swiss National Bank
Switzerland
$1.48M +$1.21M +161,700 New
State of Wisconsin Investment Board
56
State of Wisconsin Investment Board
Wisconsin
$1.13M +$45.2K +6,031 +5%
Two Sigma Investments
57
Two Sigma Investments
New York
$1.1M -$2.33K -310 -0.3%
UBS AM
58
UBS AM
Illinois
$1.07M +$873K +116,477 New
RhumbLine Advisers
59
RhumbLine Advisers
Massachusetts
$1.05M +$64.6K +8,620 +8%
SAM
60
Sectoral Asset Management
Quebec, Canada
$969K -$211K -28,200 -21%
Citadel Advisors
61
Citadel Advisors
Florida
$938K -$9.12M -1,216,732 -92%
WP
62
Woodline Partners
California
$918K -$29.6M -3,946,153 -98%
RA
63
Rosalind Advisors
Ontario, Canada
$915K -$1.5M -200,000 -67%
LP
64
LMR Partners
United Kingdom
$915K
OC
65
Oppenheimer & Co
New York
$903K -$8.68K -1,157 -1%
MCM
66
MAI Capital Management
Ohio
$901K -$5.62M -749,061 -88%
NFT
67
Nan Fung Trinity
Hong Kong
$820K +$672K +89,575 New
DP
68
Diadema Partners
New Jersey
$785K -$750K -100,000 -54%
SEI Investments
69
SEI Investments
Pennsylvania
$785K +$643K +85,798 New
Legal & General Group
70
Legal & General Group
United Kingdom
$750K +$551K +73,526 +871%
California State Teachers Retirement System (CalSTRS)
71
California State Teachers Retirement System (CalSTRS)
California
$748K +$579K +77,200 +1,717%
PP
72
PFS Partners
New Jersey
$723K
Capstone Investment Advisors
73
Capstone Investment Advisors
New York
$671K +$550K +73,287 New
SG Americas Securities
74
SG Americas Securities
New York
$591K +$484K +64,545 New
Simplex Trading
75
Simplex Trading
Illinois
$577K +$474K +63,149 New

TRVI Hedge Fund Activity: Q3 2025 in Review

164 of the 7,621 institutional investors tracked by Wall St. Rank reported a position in Trevi Therapeutics (TRVI) for Q3 2025, worth a combined $1.18B — up 89% from $627M a quarter earlier.

Buyers outnumbered sellers: 35 funds opened new TRVI positions and 23 closed out — a net gain of 12 holders — while 65 added to existing stakes and 42 trimmed.

The largest buyer was Viking Global Investors, adding an estimated $26.9M. The largest seller was Woodline Partners, cutting an estimated $29.6M.

  • 164 institutional investors held Trevi Therapeutics (TRVI) as of Q3 2025, up from 153 in Q2 2025.
  • Funds reported $1.18B of Trevi Therapeutics stock for Q3 2025, up 89% quarter-over-quarter.
  • 35 funds opened new Trevi Therapeutics positions in Q3 2025 and 23 closed out, a net change of +12 holders.
  • The largest Trevi Therapeutics buyer in Q3 2025 was Viking Global Investors, an estimated $26.9M added.
  • The largest Trevi Therapeutics seller in Q3 2025 was Woodline Partners, an estimated $29.6M sold.

Based on aggregated 13F filings for Q3 2025.