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Trevi Therapeutics

164 hedge funds and large institutions have $1.18B invested in Trevi Therapeutics in 2025 Q3 according to their latest regulatory filings, with 35 funds opening new positions, 65 increasing their positions, 42 reducing their positions, and 23 closing their positions.

New
Increased
Maintained
Reduced
Closed

89% more capital invested

Capital invested by funds: $627M → $1.18B (+$556M)

55% more repeat investments, than reductions

Existing positions increased: 65 | Existing positions reduced: 42

52% more first-time investments, than exits

New positions opened: 35 | Existing positions closed: 23

8.45% more ownership

Funds ownership: 97.75%106.2% (+8.4%)

7% more funds holding

Funds holding: 153164 (+11)

14% less funds holding in top 10

Funds holding in top 10: 76 (-1)

48% less call options, than puts

Call options by funds: $8.43M | Put options by funds: $16.3M

Holders
164
Holders Change
+11
Holders Change %
+7.19%
% of All Funds
2.15%
Holding in Top 10
6
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-14.29%
% of All Funds
0.08%
New
35
Increased
65
Reduced
42
Closed
23
Calls
$8.43M
Puts
$16.3M
Net Calls
-$7.85M
Net Calls Change
-$11.9M
Name Holding Trade Value Shares
Change
Change in
Stake
EAM
26
Eventide Asset Management
Massachusetts
$12.6M
PBPIA
27
Pivotal bioVenture Partners Investment Advisor
California
$11.5M +$830K +110,672 +10%
FLPIM
28
F.L. Putnam Investment Management
Massachusetts
$9.59M +$7.21M +961,150 +1,105%
Point72 Asset Management
29
Point72 Asset Management
Connecticut
$8.62M -$5.9M -786,747 -46%
Charles Schwab
30
Charles Schwab
California
$7.38M +$4.35M +580,396 +257%
JGC
31
J. Goldman & Co
New York
$7.25M -$1.4M -186,292 -19%
Goldman Sachs
32
Goldman Sachs
New York
$7.21M +$3.66M +488,409 +163%
Northern Trust
33
Northern Trust
Illinois
$6.74M +$1.2M +160,459 +28%
Millennium Management
34
Millennium Management
New York
$6.66M +$4.28M +570,352 +363%
Qube Research & Technologies (QRT)
35
Qube Research & Technologies (QRT)
United Kingdom
$5.96M +$1.53M +203,827 +46%
SFM
36
Sphera Funds Management
Israel
$5.89M -$1.17M -156,000 -20%
Balyasny Asset Management
37
Balyasny Asset Management
Illinois
$5.73M -$13M -1,727,940 -73%
PCM
38
Peregrine Capital Management
Minnesota
$5.68M +$4.65M +620,464 New
Prudential Financial
39
Prudential Financial
New Jersey
$5.51M +$2.82M +376,273 +166%
SCM
40
Silverarc Capital Management
Massachusetts
$5.39M +$369K +49,202 +9%
PAM
41
Panagora Asset Management
Massachusetts
$5.22M +$5.74K +766 +0.1%
EI
42
EAM Investors
California
$4.97M +$471K +62,855 +13%
BGM
43
Burkehill Global Management
New York
$4.8M
Invesco
44
Invesco
Georgia
$4.42M +$1.21M +160,731 +50%
OM
45
Opaleye Management
Massachusetts
$3.57M
SC
46
Stempoint Capital
New York
$3.21M +$2.63M +350,710 New
UBS Group
47
UBS Group
Switzerland
$2.73M -$417K -55,613 -16%
Renaissance Technologies
48
Renaissance Technologies
New York
$2.68M -$1.47M -196,000 -40%
Bank of New York Mellon
49
Bank of New York Mellon
New York
$2.07M +$450K +60,074 +36%
Barclays
50
Barclays
United Kingdom
$1.98M -$2.24M -298,591 -58%

TRVI Hedge Fund Activity: Q3 2025 in Review

164 of the 7,621 institutional investors tracked by Wall St. Rank reported a position in Trevi Therapeutics (TRVI) for Q3 2025, worth a combined $1.18B — up 89% from $627M a quarter earlier.

Buyers outnumbered sellers: 35 funds opened new TRVI positions and 23 closed out — a net gain of 12 holders — while 65 added to existing stakes and 42 trimmed.

The largest buyer was Viking Global Investors, adding an estimated $26.9M. The largest seller was Woodline Partners, cutting an estimated $29.6M.

  • 164 institutional investors held Trevi Therapeutics (TRVI) as of Q3 2025, up from 153 in Q2 2025.
  • Funds reported $1.18B of Trevi Therapeutics stock for Q3 2025, up 89% quarter-over-quarter.
  • 35 funds opened new Trevi Therapeutics positions in Q3 2025 and 23 closed out, a net change of +12 holders.
  • The largest Trevi Therapeutics buyer in Q3 2025 was Viking Global Investors, an estimated $26.9M added.
  • The largest Trevi Therapeutics seller in Q3 2025 was Woodline Partners, an estimated $29.6M sold.

Based on aggregated 13F filings for Q3 2025.