We are live on ! Find out more
STTK icon

Shattuck Labs

65 hedge funds and large institutions have $153M invested in Shattuck Labs in 2025 Q4 according to their latest regulatory filings, with 17 funds opening new positions, 18 increasing their positions, 13 reducing their positions, and 4 closing their positions.

New
Increased
Maintained
Reduced
Closed

325% more first-time investments, than exits

New positions opened: 17 | Existing positions closed: 4

76% more capital invested

Capital invested by funds: $87M → $153M (+$66.4M)

38% more repeat investments, than reductions

Existing positions increased: 18 | Existing positions reduced: 13

16% more funds holding

Funds holding: 5665 (+9)

8.79% more ownership

Funds ownership: 57.62%66.41% (+8.8%)

0% more funds holding in top 10

Funds holding in top 10: 11 (0)

Holders
65
Holders Change
+9
Holders Change %
+16.07%
% of All Funds
0.79%
Holding in Top 10
1
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.01%
New
17
Increased
18
Reduced
13
Closed
4
Calls
Puts
Net Calls
Net Calls Change
Name Holding Trade Value Shares
Change
Change in
Stake
Adage Capital Partners
1
Adage Capital Partners
Massachusetts
$23M
O
2
OrbiMed
New York
$23M
RG
3
Redmile Group
California
$20.2M
NCM
4
NEXTBio Capital Management
California
$11.5M +$7.52M +3,149,907 New
PM
5
Prosight Management
Texas
$8.69M -$7.32M -3,069,693 -56%
Vanguard Group
6
Vanguard Group
Pennsylvania
$8.68M +$595K +249,345 +12%
T. Rowe Price Associates
7
T. Rowe Price Associates
Maryland
$7.03M +$4.6M +1,926,140 New
CEI
8
Clark Estates Inc
New York
$5.39M
6CM
9
683 Capital Management
New York
$5.07M -$339K -142,216 -9%
T. Rowe Price Investment Management
10
T. Rowe Price Investment Management
Maryland
$4.95M +$3.23M +1,354,761 New
PA
11
Pinnacle Associates
New York
$4.93M -$90.9K -38,085 -3%
Bank of America
12
Bank of America
North Carolina
$4.04M -$60.3K -25,271 -2%
Point72 Asset Management
13
Point72 Asset Management
Connecticut
$3.9M +$2.55M +1,068,231 New
Geode Capital Management
14
Geode Capital Management
Massachusetts
$2.26M +$359K +150,318 +32%
Aberdeen Group
15
Aberdeen Group
United Kingdom
$1.94M +$1.04M +436,673 +462%
Marshall Wace
16
Marshall Wace
United Kingdom
$1.79M -$398K -166,741 -25%
Millennium Management
17
Millennium Management
New York
$1.74M -$509K -213,493 -31%
Two Sigma Investments
18
Two Sigma Investments
New York
$1.6M +$69.5K +29,131 +7%
BlackRock
19
BlackRock
New York
$1.53M +$17.3K +7,237 +2%
Fidelity Investments
20
Fidelity Investments
Massachusetts
$1.43M +$929K +389,233 +11,560%
Renaissance Technologies
21
Renaissance Technologies
New York
$1.24M +$295K +123,833 +57%
TD Asset Management
22
TD Asset Management
Ontario, Canada
$916K +$599K +251,050 New
State Street
23
State Street
Massachusetts
$786K +$92.3K +38,700 +22%
SFM
24
Sphera Funds Management
Israel
$713K +$466K +195,212 New
Two Sigma Advisers
25
Two Sigma Advisers
New York
$623K +$138K +57,923 +51%

STTK Hedge Fund Activity: Q4 2025 in Review

65 of the 8,225 institutional investors tracked by Wall St. Rank reported a position in Shattuck Labs (STTK) for Q4 2025, worth a combined $153M — up 76% from $87M a quarter earlier.

Buyers outnumbered sellers: 17 funds opened new STTK positions and 4 closed out — a net gain of 13 holders — while 18 added to existing stakes and 13 trimmed.

The largest buyer was T. Rowe Price Associates, opening a new position worth an estimated $4.6M. The largest seller was Prosight Management, cutting an estimated $7.32M.

  • 65 institutional investors held Shattuck Labs (STTK) as of Q4 2025, up from 56 in Q3 2025.
  • Funds reported $153M of Shattuck Labs stock for Q4 2025, up 76% quarter-over-quarter.
  • 17 funds opened new Shattuck Labs positions in Q4 2025 and 4 closed out, a net change of +13 holders.
  • The largest Shattuck Labs buyer in Q4 2025 was T. Rowe Price Associates, an estimated $4.6M added.
  • The largest Shattuck Labs seller in Q4 2025 was Prosight Management, an estimated $7.32M sold.

Based on aggregated 13F filings for Q4 2025.