Shattuck LabsSTTK
About: Shattuck Labs Inc is a biotechnology company specializing in the development of potential treatments for inflammatory and immune-mediated diseases. It is developing a potentially first-in-class antibody for the treatment of inflammatory bowel disease (IBD) and other inflammatory and immune-mediated diseases. The company's expertise in protein engineering and the development of novel tumor necrosis factor (TNF) receptor therapeutics comes together in its main program, SL-325, which has the potential to be a first-in-class death receptor 3 (DR3) antagonist antibody. In addition, the company is developing SL-425, a half-life extended version of SL-325, and multiple other preclinical DR3-based bispecific antibodies, for the treatment of patients with IBD.
Employees: 44
Fund manager confidence
Based on 2025 Q1 regulatory disclosures by fund managers ($100M+ AUM)
29% more first-time investments, than exits
New positions opened: 9 | Existing positions closed: 7
0% more funds holding
Funds holding: 75 [Q4 2024] → 75 (+0) [Q1 2025]
0% more funds holding in top 10
Funds holding in top 10: 1 [Q4 2024] → 1 (+0) [Q1 2025]
1.15% less ownership
Funds ownership: 66.26% [Q4 2024] → 65.11% (-1.15%) [Q1 2025]
23% less capital invested
Capital invested by funds: $38.3M [Q4 2024] → $29.6M (-$8.65M) [Q1 2025]
33% less repeat investments, than reductions
Existing positions increased: 16 | Existing positions reduced: 24
Research analyst outlook
1 Wall Street Analyst provided 1 year price targets over the past 3 months
1 analyst rating
Leerink Partners Faisal Khurshid | 296%upside $4 | Outperform Initiated | 17 Mar 2025 |
Financial journalist opinion









