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Shattuck Labs
STTK

56 hedge funds and large institutions have $87M invested in Shattuck Labs in 2025 Q3 according to their latest regulatory filings, with 14 funds opening new positions, 11 increasing their positions, 23 reducing their positions, and 18 closing their positions.

New
Increased
Maintained
Reduced
Closed

284% more capital invested

Capital invested by funds: $22.7M → $87M (+$64.3M)

0% more funds holding in top 10

Funds holding in top 10: 1 → 1 (0)

2.27% less ownership

Funds ownership: 59.89% → 57.62% (-2.3%)

8% less funds holding

Funds holding: 61 → 56 (-5)

22% less first-time investments, than exits

New positions opened: 14 | Existing positions closed: 18

52% less repeat investments, than reductions

Existing positions increased: 11 | Existing positions reduced: 23

Holders
56
Holders Change
-5
Holders Change %
-8.2%
% of All Funds
0.73%
Holding in Top 10
1
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.01%
New
14
Increased
11
Reduced
23
Closed
18
Calls
$224K
Puts
–
Net Calls
+$224K
Net Calls Change
+$195K

Top Buyers

Rank Fund Capital Flow
1
O
OrbiMed
New York
+$7.72M
2
Adage Capital Partners
Adage Capital Partners
Massachusetts
+$2M
3
Bank of America
Bank of America
North Carolina
+$1.34M
4
Marshall Wace
Marshall Wace
United Kingdom
+$803K
5
6CM
683 Capital Management
New York
+$535K

Top Sellers

Rank Fund Capital Flow
1
PM
Prosight Management
Texas
-$1.45M
2
BlackRock
BlackRock
New York
-$575K
3
Goldman Sachs
Goldman Sachs
New York
-$377K
4
UBS Group
UBS Group
Switzerland
-$327K
5
Jane Street
Jane Street
New York
-$233K
Name Holding Trade Value Shares
Change 		Change in
Stake
PD
51
Point72 (DIFC)
United Arab Emirates
$884 -$881 -720 -66%
JP Morgan Chase
52
JP Morgan Chase
New York
$724 -$695 -568 -65%
SS
53
SBI Securities
Japan
$220 -$61 -50 -35%
Optiver Holding
54
Optiver Holding
Netherlands
$158 +$81 +66 New
AAP
55
Arax Advisory Partners
Colorado
$33 +$17 +14 New
YIH
56
Y-Intercept (HK)
Hong Kong
– -$97.5K -123,172 Closed
ACM
57
ADAR1 Capital Management
Texas
– -$81.5K -102,948 Closed
AQR Capital Management
58
AQR Capital Management
Connecticut
– -$30.1K -38,004 Closed
Jacobs Levy Equity Management
59
Jacobs Levy Equity Management
New Jersey
– -$28.3K -35,780 Closed
JG
60
Jain Global
New York
– -$27.3K -34,525 Closed
STA
61
Summit Trail Advisors
New York
– -$18.7K -23,629 Closed
MCFP
62
Mallini Complete Financial Planning
Florida
– -$1.79K -22,632 Closed
TRCT
63
Tower Research Capital (TRC)
New York
– -$13.4K -16,886 Closed
HSBC Holdings
64
HSBC Holdings
United Kingdom
– -$12.9K -16,122 Closed
Carson Wealth (CWM LLC)
65
Carson Wealth (CWM LLC)
Nebraska
– -$3.5K -2,862 -96%
BFP
66
Briaud Financial Planning
Texas
– -$1K -2,227 Closed
Barclays
67
Barclays
United Kingdom
– -$1.67K -2,114 Closed
Simplex Trading
68
Simplex Trading
Illinois
– -$1.41K -1,156 Closed
Wells Fargo
69
Wells Fargo
California
– -$674 -851 Closed
Nisa Investment Advisors
70
Nisa Investment Advisors
Missouri
– -$543 -686 Closed
Raymond James Financial
71
Raymond James Financial
Florida
– -$198 -250 Closed
CA
72
Clearstead Advisors
Ohio
– -$123 -155 Closed
EWA
73
EverSource Wealth Advisors
Alabama
– -$89 -112 Closed
TWD
74
True Wealth Design
Ohio
– -$37 -46 Closed
1 2
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STTK Hedge Fund Activity: Q3 2025 in Review

56 of the 7,620 institutional investors tracked by Wall St. Rank reported a position in Shattuck Labs (STTK) for Q3 2025, worth a combined $87M — up 284% from $22.7M a quarter earlier.

Sellers outnumbered buyers: 18 funds closed out of STTK and 14 opened new positions — a net loss of 4 holders — while 23 trimmed existing stakes and 11 added.

The largest buyer was OrbiMed, opening a new position worth an estimated $7.72M. The largest seller was Prosight Management, cutting an estimated $1.45M.

  • 56 institutional investors held Shattuck Labs (STTK) as of Q3 2025, down from 61 in Q2 2025.
  • Funds reported $87M of Shattuck Labs stock for Q3 2025, up 284% quarter-over-quarter.
  • 14 funds opened new Shattuck Labs positions in Q3 2025 and 18 closed out, a net change of -4 holders.
  • The largest Shattuck Labs buyer in Q3 2025 was OrbiMed, an estimated $7.72M added.
  • The largest Shattuck Labs seller in Q3 2025 was Prosight Management, an estimated $1.45M sold.

Based on aggregated 13F filings for Q3 2025.