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Shattuck Labs

84 hedge funds and large institutions have $360M invested in Shattuck Labs in 2026 Q1 according to their latest regulatory filings, with 24 funds opening new positions, 33 increasing their positions, 14 reducing their positions, and 4 closing their positions.

New
Increased
Maintained
Reduced
Closed

500% more first-time investments, than exits

New positions opened: 24 | Existing positions closed: 4

200% more funds holding in top 10

Funds holding in top 10: 13 (+2)

136% more repeat investments, than reductions

Existing positions increased: 33 | Existing positions reduced: 14

135% more capital invested

Capital invested by funds: $153M → $360M (+$207M)

29% more funds holding

Funds holding: 6584 (+19)

11.93% more ownership

Funds ownership: 66.41%78.35% (+12%)

Holders
84
Holders Change
+19
Holders Change %
+29.23%
% of All Funds
1.03%
Holding in Top 10
3
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+200%
% of All Funds
0.04%
New
24
Increased
33
Reduced
14
Closed
4
Calls
$16K
Puts
Net Calls
+$16K
Net Calls Change
+$16K
Name Holding Trade Value Shares
Change
Change in
Stake
Two Sigma Investments
26
Two Sigma Investments
New York
$2.03M -$577K -121,717 -28%
DP
27
Diadema Partners
New Jersey
$1.89M +$1.39M +293,664 New
AG
28
Algert Global
California
$1.84M +$1.36M +286,072 New
SFM
29
Sphera Funds Management
Israel
$1.81M +$406K +85,574 +44%
State Street
30
State Street
Massachusetts
$1.7M +$229K +48,350 +22%
Hudson Bay Capital Management
31
Hudson Bay Capital Management
Connecticut
$1.47M +$1.09M +228,817 New
Morgan Stanley
32
Morgan Stanley
New York
$1.29M +$863K +182,028 +1,005%
Deutsche Bank
33
Deutsche Bank
Germany
$1.25M +$924K +194,773 New
Goldman Sachs
34
Goldman Sachs
New York
$1.23M +$300K +63,277 +49%
Acadian Asset Management
35
Acadian Asset Management
Massachusetts
$1.17M +$493K +103,879 +131%
Dimensional Fund Advisors
36
Dimensional Fund Advisors
Texas
$1M +$628K +132,450 +571%
Citadel Advisors
37
Citadel Advisors
Florida
$952K +$376K +79,175 +115%
XT
38
XTX Topco
Cayman Islands
$916K +$558K +117,593 +473%
Manulife (Manufacturers Life Insurance)
39
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$915K +$34.4K +7,244 +5%
Connor, Clark & Lunn Investment Management (CC&L)
40
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
$896K +$349K +73,570 +112%
Qube Research & Technologies (QRT)
41
Qube Research & Technologies (QRT)
United Kingdom
$815K +$418K +88,041 +227%
Northern Trust
42
Northern Trust
Illinois
$811K -$91.9K -19,384 -13%
Barclays
43
Barclays
United Kingdom
$771K +$569K +119,879 New
HF
44
HRT Financial
New York
$583K +$430K +90,698 New
Bank of New York Mellon
45
Bank of New York Mellon
New York
$577K -$97.8K -20,620 -19%
Bank of America
46
Bank of America
North Carolina
$514K -$4.87M -1,026,693 -93%
BHCM
47
Brevan Howard Capital Management
Jersey
$511K +$377K +79,476 New
LFWA
48
LBJ Family Wealth Advisors
Texas
$490K
Citigroup
49
Citigroup
New York
$482K +$238K +50,173 +202%
PAP
50
Persistent Asset Partners
Hong Kong
$477K +$352K +74,229 New