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Shattuck Labs
STTK

65 hedge funds and large institutions have $153M invested in Shattuck Labs in 2025 Q4 according to their latest regulatory filings, with 17 funds opening new positions, 18 increasing their positions, 13 reducing their positions, and 4 closing their positions.

New
Increased
Maintained
Reduced
Closed

325% more first-time investments, than exits

New positions opened: 17 | Existing positions closed: 4

76% more capital invested

Capital invested by funds: $87M → $153M (+$66.4M)

38% more repeat investments, than reductions

Existing positions increased: 18 | Existing positions reduced: 13

16% more funds holding

Funds holding: 56 → 65 (+9)

8.79% more ownership

Funds ownership: 57.62% → 66.41% (+8.8%)

0% more funds holding in top 10

Funds holding in top 10: 1 → 1 (0)

Holders
65
Holders Change
+9
Holders Change %
+16.07%
% of All Funds
0.79%
Holding in Top 10
1
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.01%
New
17
Increased
18
Reduced
13
Closed
4
Calls
–
Puts
–
Net Calls
–
Net Calls Change
–

Top Buyers

Rank Fund Capital Flow
1
T. Rowe Price Associates
T. Rowe Price Associates
Maryland
+$4.6M
2
T. Rowe Price Investment Management
T. Rowe Price Investment Management
Maryland
+$3.23M
3
Point72 Asset Management
Point72 Asset Management
Connecticut
+$2.55M
4
Aberdeen Group
Aberdeen Group
United Kingdom
+$1.04M
5
Fidelity Investments
Fidelity Investments
Massachusetts
+$929K

Top Sellers

Rank Fund Capital Flow
1
PM
Prosight Management
Texas
-$7.32M
2
Acadian Asset Management
Acadian Asset Management
Massachusetts
-$596K
3
Millennium Management
Millennium Management
New York
-$509K
4
Marshall Wace
Marshall Wace
United Kingdom
-$398K
5
6CM
683 Capital Management
New York
-$339K
Name Holding Trade Value Shares
Change 		Change in
Stake
Pathstone Holdings
26
Pathstone Holdings
New Jersey
$573K – – –
Susquehanna International Group
27
Susquehanna International Group
Pennsylvania
$542K +$192K +80,311 +118%
Northern Trust
28
Northern Trust
Illinois
$531K +$129K +54,173 +59%
Manulife (Manufacturers Life Insurance)
29
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$486K +$322K +135,056 New
Goldman Sachs
30
Goldman Sachs
New York
$468K +$266K +111,365 +663%
Bank of New York Mellon
31
Bank of New York Mellon
New York
$403K – – –
LFWA
32
LBJ Family Wealth Advisors
Texas
$300K – – –
Acadian Asset Management
33
Acadian Asset Management
Massachusetts
$289K -$596K -249,921 -76%
Citadel Advisors
34
Citadel Advisors
Florida
$251K +$164K +68,846 New
Connor, Clark & Lunn Investment Management (CC&L)
35
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
$240K +$157K +65,734 New
Squarepoint
36
Squarepoint
New York
$236K +$109K +45,525 +236%
Jane Street
37
Jane Street
New York
$197K -$107K -45,001 -45%
BCM
38
Bridgeway Capital Management
Texas
$154K – – –
EWA
39
EP Wealth Advisors
California
$150K +$98.2K +41,167 New
PSC
40
Piper Sandler & Co
Minnesota
$144K – – –
Qube Research & Technologies (QRT)
41
Qube Research & Technologies (QRT)
United Kingdom
$141K +$54.4K +22,806 +143%
Invesco
42
Invesco
Georgia
$103K +$67.4K +28,231 New
OAC
43
OMERS Administration Corp
Ontario, Canada
$96.7K +$63.2K +26,500 New
RWM
44
Ritholtz Wealth Management
New York
$94.9K – – –
XT
45
XTX Topco
Cayman Islands
$90.8K -$3.23K -1,353 -5%
Citigroup
46
Citigroup
New York
$90.6K +$23.2K +9,724 +64%
Dimensional Fund Advisors
47
Dimensional Fund Advisors
Texas
$84.7K +$55.3K +23,192 New
MCFP
48
Mallini Complete Financial Planning
Florida
$82.6K +$54K +22,632 New
CL
49
Choreo LLC
Illinois
$76.5K – – –
Charles Schwab
50
Charles Schwab
California
$76.2K – – –
1
2
3

STTK Hedge Fund Activity: Q4 2025 in Review

65 of the 8,225 institutional investors tracked by Wall St. Rank reported a position in Shattuck Labs (STTK) for Q4 2025, worth a combined $153M — up 76% from $87M a quarter earlier.

Buyers outnumbered sellers: 17 funds opened new STTK positions and 4 closed out — a net gain of 13 holders — while 18 added to existing stakes and 13 trimmed.

The largest buyer was T. Rowe Price Associates, opening a new position worth an estimated $4.6M. The largest seller was Prosight Management, cutting an estimated $7.32M.

  • 65 institutional investors held Shattuck Labs (STTK) as of Q4 2025, up from 56 in Q3 2025.
  • Funds reported $153M of Shattuck Labs stock for Q4 2025, up 76% quarter-over-quarter.
  • 17 funds opened new Shattuck Labs positions in Q4 2025 and 4 closed out, a net change of +13 holders.
  • The largest Shattuck Labs buyer in Q4 2025 was T. Rowe Price Associates, an estimated $4.6M added.
  • The largest Shattuck Labs seller in Q4 2025 was Prosight Management, an estimated $7.32M sold.

Based on aggregated 13F filings for Q4 2025.