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Stoke Therapeutics
STOK

Overview Fund Activity

133 hedge funds and large institutions have $744M invested in Stoke Therapeutics in 2025 Q2 according to their latest regulatory filings, with 23 funds opening new positions, 50 increasing their positions, 34 reducing their positions, and 17 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
133
Holders Change
+6
Holders Change %
+4.72%
% of All Funds
1.78%
Holding in Top 10
4
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+33.33%
% of All Funds
0.05%
New
23
Increased
50
Reduced
34
Closed
17
Calls
$35K
Puts
$672K
Net Calls
-$637K
Net Calls Change
+$276K

Top Buyers

1
Fidelity Investments
Fidelity Investments
Massachusetts
$84.1M
2
PCH
Polar Capital Holdings
United Kingdom
$10M
3
Corient Private Wealth
Corient Private Wealth
Florida
$7.49M
4
OM
Opaleye Management
Massachusetts
$6.38M
5
UBS Group
UBS Group
Switzerland
$4M

Top Sellers

1
ST
Skorpios Trust
Cyprus
$37M
2
CC
Checkpoint Capital
California
$0
3
Assenagon Asset Management
Assenagon Asset Management
Luxembourg
$6.11M
4
Goldman Sachs
Goldman Sachs
New York
$14.8M
5
Jacobs Levy Equity Management
Jacobs Levy Equity Management
New Jersey
$1.4M
Name Holding Trade Value Shares
Change 		Shares
Change %
Fidelity Investments
1
Fidelity Investments
Massachusetts
$84.1M +$55.3M +4,871,045 +192%
BlackRock
2
BlackRock
New York
$67.2M +$705K +62,131 +1%
LCM
3
Lynx1 Capital Management
Puerto Rico
$61.3M +$1.28M +112,745 +2%
RI
4
RTW Investments
New York
$58.2M – – –
BBA
5
Baker Bros. Advisors
New York
$52.6M – – –
RG
6
Redmile Group
California
$49.7M -$1.25M -110,050 -2%
Morgan Stanley
7
Morgan Stanley
New York
$40.6M -$191K -16,849 -0.5%
ST
8
Skorpios Trust
Cyprus
$37M -$41.4M -3,650,000 -53%
Toronto Dominion Bank
9
Toronto Dominion Bank
Ontario, Canada
$36M – – –
Vanguard Group
10
Vanguard Group
Pennsylvania
$33.4M +$1.84M +162,056 +6%
Marshall Wace
11
Marshall Wace
United Kingdom
$26.1M +$1.92M +168,771 +8%
SL
12
Siren LLC
Connecticut
$25.5M – – –
State Street
13
State Street
Massachusetts
$16.9M -$1M -88,127 -6%
Goldman Sachs
14
Goldman Sachs
New York
$14.8M -$4.09M -360,658 -22%
Geode Capital Management
15
Geode Capital Management
Massachusetts
$11M +$805K +70,935 +8%
PCH
16
Polar Capital Holdings
United Kingdom
$10M +$10M +883,646 New
MB
17
MPM BioImpact
Massachusetts
$8.96M +$1.09M +95,710 +14%
Dimensional Fund Advisors
18
Dimensional Fund Advisors
Texas
$7.65M +$104K +9,149 +1%
Corient Private Wealth
19
Corient Private Wealth
Florida
$7.49M +$7.49M +659,834 New
OM
20
Opaleye Management
Massachusetts
$6.38M +$2.98M +262,120 +87%
Bank of America
21
Bank of America
North Carolina
$6.22M +$173K +15,206 +3%
Assenagon Asset Management
22
Assenagon Asset Management
Luxembourg
$6.11M -$4.79M -421,630 -44%
GIM
23
Granahan Investment Management
Massachusetts
$6.04M -$1.45M -128,017 -19%
DCM
24
DAFNA Capital Management
California
$5.7M +$658K +57,974 +13%
TCM
25
Tang Capital Management
California
$5.68M – – –
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