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Stoke Therapeutics

126 hedge funds and large institutions have $422M invested in Stoke Therapeutics in 2025 Q1 according to their latest regulatory filings, with 23 funds opening new positions, 45 increasing their positions, 30 reducing their positions, and 27 closing their positions.

New
Increased
Maintained
Reduced
Closed

50% more repeat investments, than reductions

Existing positions increased: 45 | Existing positions reduced: 30

7.59% more ownership

Funds ownership: 109.61%117.2% (+7.6%)

0% more funds holding in top 10

Funds holding in top 10: 33 (0)

3% less funds holding

Funds holding: 130126 (-4)

15% less first-time investments, than exits

New positions opened: 23 | Existing positions closed: 27

34% less capital invested

Capital invested by funds: $640M → $422M (-$219M)

94% less call options, than puts

Call options by funds: $60K | Put options by funds: $973K

Holders
126
Holders Change
-4
Holders Change %
-3.08%
% of All Funds
1.69%
Holding in Top 10
3
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.04%
New
23
Increased
45
Reduced
30
Closed
27
Calls
$60K
Puts
$973K
Net Calls
-$913K
Net Calls Change
-$688K
Name Holding Trade Value Shares
Change
Change in
Stake
ST
1
Skorpios Trust
Cyprus
$45.9M
BlackRock
2
BlackRock
New York
$39M -$234K -25,075 -0.4%
LCM
3
Lynx1 Capital Management
Puerto Rico
$35.2M +$977K +104,738 +2%
RI
4
RTW Investments
New York
$34.1M
BBA
5
Baker Bros. Advisors
New York
$30.8M
RG
6
Redmile Group
California
$29.8M -$1M -107,648 -2%
Morgan Stanley
7
Morgan Stanley
New York
$23.9M +$1.43M +153,581 +4%
Toronto Dominion Bank
8
Toronto Dominion Bank
Ontario, Canada
$21.1M
Vanguard Group
9
Vanguard Group
Pennsylvania
$18.5M +$494K +53,004 +2%
Fidelity Investments
10
Fidelity Investments
Massachusetts
$16.9M +$22.2M +2,376,741 +1,439%
SL
11
Siren LLC
Connecticut
$14.9M +$2.31M +247,347 +12%
Marshall Wace
12
Marshall Wace
United Kingdom
$14.2M +$11M +1,180,351 +124%
Goldman Sachs
13
Goldman Sachs
New York
$11.1M +$2.73M +293,072 +21%
State Street
14
State Street
Massachusetts
$10.5M -$115K -12,380 -0.8%
Assenagon Asset Management
15
Assenagon Asset Management
Luxembourg
$6.38M -$3.65M -391,322 -29%
Geode Capital Management
16
Geode Capital Management
Massachusetts
$6M +$232K +24,891 +3%
CC
17
Checkpoint Capital
California
$4.86M +$3.97M +425,330 +139%
MB
18
MPM BioImpact
Massachusetts
$4.62M +$76.1K +8,162 +1%
Dimensional Fund Advisors
19
Dimensional Fund Advisors
Texas
$4.42M +$1.17M +125,835 +23%
GIM
20
Granahan Investment Management
Massachusetts
$4.39M +$865K +92,741 +16%
Bank of America
21
Bank of America
North Carolina
$3.54M +$4.88M +523,793 +5,762%
TCM
22
Tang Capital Management
California
$3.33M +$1.86M +200,000 +67%
DCM
23
DAFNA Capital Management
California
$2.95M +$2.54M +272,901 +160%
EAM
24
Erste Asset Management
Austria
$2.67M +$3.69M +396,000 New
Jacobs Levy Equity Management
25
Jacobs Levy Equity Management
New Jersey
$2.38M +$3.33M +357,248 New

STOK Hedge Fund Activity: Q1 2025 in Review

126 of the 7,458 institutional investors tracked by Wall St. Rank reported a position in Stoke Therapeutics (STOK) for Q1 2025, worth a combined $422M — down 34% from $640M a quarter earlier.

Sellers outnumbered buyers: 27 funds closed out of STOK and 23 opened new positions — a net loss of 4 holders — while 30 trimmed existing stakes and 45 added.

The largest buyer was Fidelity Investments, adding an estimated $22.2M. The largest seller was Assenagon Asset Management, cutting an estimated $3.65M.

  • 126 institutional investors held Stoke Therapeutics (STOK) as of Q1 2025, down from 130 in Q4 2024.
  • Funds reported $422M of Stoke Therapeutics stock for Q1 2025, down 34% quarter-over-quarter.
  • 23 funds opened new Stoke Therapeutics positions in Q1 2025 and 27 closed out, a net change of -4 holders.
  • The largest Stoke Therapeutics buyer in Q1 2025 was Fidelity Investments, an estimated $22.2M added.
  • The largest Stoke Therapeutics seller in Q1 2025 was Assenagon Asset Management, an estimated $3.65M sold.

Based on aggregated 13F filings for Q1 2025.