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Stoke Therapeutics

126 hedge funds and large institutions have $422M invested in Stoke Therapeutics in 2025 Q1 according to their latest regulatory filings, with 23 funds opening new positions, 45 increasing their positions, 30 reducing their positions, and 27 closing their positions.

New
Increased
Maintained
Reduced
Closed

50% more repeat investments, than reductions

Existing positions increased: 45 | Existing positions reduced: 30

7.59% more ownership

Funds ownership: 109.61%117.2% (+7.6%)

0% more funds holding in top 10

Funds holding in top 10: 33 (0)

3% less funds holding

Funds holding: 130126 (-4)

15% less first-time investments, than exits

New positions opened: 23 | Existing positions closed: 27

34% less capital invested

Capital invested by funds: $640M → $422M (-$219M)

94% less call options, than puts

Call options by funds: $60K | Put options by funds: $973K

Holders
126
Holders Change
-4
Holders Change %
-3.08%
% of All Funds
1.69%
Holding in Top 10
3
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.04%
New
23
Increased
45
Reduced
30
Closed
27
Calls
$60K
Puts
$973K
Net Calls
-$913K
Net Calls Change
-$688K
Name Holding Trade Value Shares
Change
Change in
Stake
Squarepoint
126
Squarepoint
New York
-$1.33M -120,242 Closed
EAM
127
Exome Asset Management
New York
-$1.25M -113,096 Closed
Group One Trading
128
Group One Trading
Illinois
-$973K -104,411 Closed
PAM
129
Panagora Asset Management
Massachusetts
-$1.15M -104,272 Closed
Voloridge Investment Management
130
Voloridge Investment Management
Florida
-$958K -86,888 Closed
Two Sigma Investments
131
Two Sigma Investments
New York
-$595K -53,950 Closed
Los Angeles Capital Management
132
Los Angeles Capital Management
California
-$479K -43,438 Closed
EC
133
EntryPoint Capital
New York
-$353K -31,968 Closed
PCM
134
Prelude Capital Management
New York
-$326K -29,528 Closed
D.E. Shaw & Co
135
D.E. Shaw & Co
New York
-$309K -28,043 Closed
EGM
136
Engineers Gate Manager
New York
-$276K -25,005 Closed
Tudor Investment Corp
137
Tudor Investment Corp
Connecticut
-$201K -18,258 Closed
Verition Fund Management
138
Verition Fund Management
Connecticut
-$167K -15,160 Closed
PP
139
PDT Partners
New York
-$154K -13,942 Closed
VOYA Investment Management
140
VOYA Investment Management
Georgia
-$122K -11,100 Closed
SG Americas Securities
141
SG Americas Securities
New York
-$119K -10,768 Closed
Ameriprise
142
Ameriprise
Minnesota
-$116K -10,527 Closed
Teacher Retirement System of Texas
143
Teacher Retirement System of Texas
Texas
-$113K -10,219 Closed
IC
144
Ikarian Capital
Texas
-$75K -6,798 Closed
VEA
145
Virtus ETF Advisers
New York
-$63.6K -5,770 Closed
SO
146
STRS Ohio
Ohio
-$41.9K -3,800 Closed
Carson Wealth (CWM LLC)
147
Carson Wealth (CWM LLC)
Nebraska
-$7.42K -796 -95%
Royal Bank of Canada
148
Royal Bank of Canada
Ontario, Canada
-$6.42K -689 -93%
RS
149
R Squared
Hong Kong
-$4.85K -440 Closed
CIAM
150
Caitong International Asset Management
Hong Kong
-$651 -59 Closed

STOK Hedge Fund Activity: Q1 2025 in Review

126 of the 7,458 institutional investors tracked by Wall St. Rank reported a position in Stoke Therapeutics (STOK) for Q1 2025, worth a combined $422M — down 34% from $640M a quarter earlier.

Sellers outnumbered buyers: 27 funds closed out of STOK and 23 opened new positions — a net loss of 4 holders — while 30 trimmed existing stakes and 45 added.

The largest buyer was Fidelity Investments, adding an estimated $22.2M. The largest seller was Assenagon Asset Management, cutting an estimated $3.65M.

  • 126 institutional investors held Stoke Therapeutics (STOK) as of Q1 2025, down from 130 in Q4 2024.
  • Funds reported $422M of Stoke Therapeutics stock for Q1 2025, down 34% quarter-over-quarter.
  • 23 funds opened new Stoke Therapeutics positions in Q1 2025 and 27 closed out, a net change of -4 holders.
  • The largest Stoke Therapeutics buyer in Q1 2025 was Fidelity Investments, an estimated $22.2M added.
  • The largest Stoke Therapeutics seller in Q1 2025 was Assenagon Asset Management, an estimated $3.65M sold.

Based on aggregated 13F filings for Q1 2025.