Two Sigma Investments
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Two Sigma Investments’s Stoke Therapeutics STOK Stock Holding History

Two Sigma Investments’s Portfolio STOK Stock Details STOK Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2025
Q1 		– Sell
-53,950
Closed -$595K – 3475
2024
Q4 		$595K Sell
53,950
-62,728
-54% -$771K ﹤0.01% 2458
2024
Q3 		$1.43M Buy
116,678
+1,773
+2% +$25.1K ﹤0.01% 1889
2024
Q2 		$1.55M Buy
114,905
+99,405
+641% +$1.34M ﹤0.01% 1727
2024
Q1 		$209K Buy
15,500
+4,300
+38% +$26.1K ﹤0.01% 2698
2023
Q4 		$58.9K Sell
11,200
-17,100
-60% -$73.1K ﹤0.01% 2983
2023
Q3 		$112K Buy
28,300
+7,800
+38% +$51.3K ﹤0.01% 2731
2023
Q2 		$218K Buy
20,500
+3,500
+21% +$37.2K ﹤0.01% 2617
2023
Q1 		$142K Sell
17,000
-4,754
-22% -$42.9K ﹤0.01% 2623
2022
Q4 		$201K Sell
21,754
-15,990
-42% -$166K ﹤0.01% 2394
2022
Q3 		$485K Buy
37,744
+21,741
+136% +$346K ﹤0.01% 1795
2022
Q2 		$211K Buy
16,003
+4,761
+42% +$72.3K ﹤0.01% 2144
2022
Q1 		$237K Sell
11,242
-11,285
-50% -$226K ﹤0.01% 2295
2021
Q4 		$540K Sell
22,527
-58,022
-72% -$1.38M ﹤0.01% 3182
2021
Q3 		$2.05M Sell
80,549
-25,365
-24% -$707K ﹤0.01% 1971
2021
Q2 		$3.56M Sell
105,914
-21,452
-17% -$758K 0.01% 1425
2021
Q1 		$4.95M Buy
127,366
+102,426
+411% +$5.83M 0.01% 1051
2020
Q4 		$1.54M Buy
+24,940
New +$1.14M ﹤0.01% 1672

Other funds holding STOK

ST
Skorpios Trust Limassol, Cyprus $53.2M AUM 90.96% 1-Year Est. Return
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
LCM
Lynx1 Capital Management San Juan, Puerto Rico $633M AUM 173.22% 1-Year Est. Return
RI
RTW Investments New York $10B AUM 135.35% 1-Year Est. Return
BBA
Baker Bros. Advisors New York $17.4B AUM 131.5% 1-Year Est. Return
RG
Redmile Group San Francisco, California $1.51B AUM 164.17% 1-Year Est. Return
Morgan Stanley
Morgan Stanley New York $1.66T AUM 25.57% 1-Year Est. Return
Toronto Dominion Bank
Toronto Dominion Bank Toronto, Ontario, Ontario, Canada $69.7B AUM 40.86% 1-Year Est. Return
Vanguard Group
Vanguard Group Malvern, Pennsylvania $6.9T AUM 27.45% 1-Year Est. Return
Fidelity Investments
Fidelity Investments Boston, Massachusetts $1.9T AUM 41.92% 1-Year Est. Return

Two Sigma Investments's STOK Position: Q1 2025 in Review

Two Sigma Investments sold out of Stoke Therapeutics (STOK) in Q1 2025, closing a stake of 53,950 shares — an estimated $595K sold.

Two Sigma Investments first reported a position in STOK in Q4 2020 and held it in 17 quarters. The position peaked at $4.95M in Q1 2021. 126 funds tracked by Wall St. Rank hold STOK as of Q1 2025.

  • Two Sigma Investments reported no remaining Stoke Therapeutics position as of Q1 2025 after selling out during the quarter.
  • Two Sigma Investments sold 53,950 Stoke Therapeutics shares in Q1 2025, an estimated $595K.
  • Two Sigma Investments first reported a position in Stoke Therapeutics in Q4 2020 and held it in 17 quarters.
  • Two Sigma Investments's Stoke Therapeutics position peaked at $4.95M in Q1 2021.
  • 126 funds tracked by Wall St. Rank held Stoke Therapeutics as of Q1 2025.

Based on Two Sigma Investments's 13F filing for Q1 2025, filed 15 May 2025.