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Summit Therapeutics

222 hedge funds and large institutions have $2.25B invested in Summit Therapeutics in 2026 Q1 according to their latest regulatory filings, with 58 funds opening new positions, 83 increasing their positions, 49 reducing their positions, and 37 closing their positions.

New
Increased
Maintained
Reduced
Closed

69% more repeat investments, than reductions

Existing positions increased: 83 | Existing positions reduced: 49

57% more first-time investments, than exits

New positions opened: 58 | Existing positions closed: 37

9% more capital invested

Capital invested by funds: $2.06B → $2.25B (+$192M)

8% more funds holding

Funds holding: 206222 (+16)

0.06% more ownership

Funds ownership: 15.27%15.34% (+0.06%)

0% more funds holding in top 10

Funds holding in top 10: 33 (0)

15% less call options, than puts

Call options by funds: $39.9M | Put options by funds: $46.7M

Holders
222
Holders Change
+16
Holders Change %
+7.77%
% of All Funds
2.73%
Holding in Top 10
3
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.04%
New
58
Increased
83
Reduced
49
Closed
37
Calls
$39.9M
Puts
$46.7M
Net Calls
-$6.79M
Net Calls Change
+$13.4M
Name Holding Trade Value Shares
Change
Change in
Stake
ProShare Advisors
101
ProShare Advisors
Maryland
$658K +$29.2K +1,805 +5%
LP
102
LMR Partners
United Kingdom
$647K -$664K -41,078 -55%
Ohio Public Employees Retirement System (OPERS)
103
Ohio Public Employees Retirement System (OPERS)
Ohio
$645K -$18.7K -1,159 -3%
Legal & General Group
104
Legal & General Group
United Kingdom
$605K +$73.3K +4,533 +17%
Cetera Investment Advisers
105
Cetera Investment Advisers
Illinois
$564K +$481K +29,738 New
VAM
106
Vanguard Asset Management
$542K +$463K +28,611 New
MC
107
Machina Capital
France
$497K +$236K +14,563 +125%
GVAG
108
Great Valley Advisor Group
Delaware
$486K
CIBC Asset Management
109
CIBC Asset Management
Ontario, Canada
$461K
BCV
110
Banque Cantonale Vaudoise
Switzerland
$453K +$387K +23,916 New
TRCT
111
Tower Research Capital (TRC)
New York
$449K +$383K +23,703 New
VC
112
VarCov Co
Connecticut
$446K +$380K +23,509 New
CCM
113
Capstone Capital Management
$439K -$81.6K -5,044 -18%
SSA
114
Schonfeld Strategic Advisors
New York
$427K -$77.6K -4,799 -18%
WG
115
Winton Group
United Kingdom
$425K +$362K +22,400 New
Allianz Asset Management
116
Allianz Asset Management
Germany
$421K
ET
117
Entropy Technologies
New York
$413K -$54.6K -3,379 -13%
Raymond James Financial
118
Raymond James Financial
Florida
$396K +$49.4K +3,053 +17%
X
119
Xponance
Pennsylvania
$381K +$41.6K +2,572 +15%
PCM
120
Prelude Capital Management
New York
$379K +$323K +20,000 New
VW
121
Vance Wealth
California
$379K
SEI Investments
122
SEI Investments
Pennsylvania
$373K +$156K +9,618 +96%
NYLIM
123
New York Life Investment Management
New York
$370K +$316K +19,521 New
AllianceBernstein
124
AllianceBernstein
Tennessee
$347K -$12.2K -753 -4%
Russell Investments Group
125
Russell Investments Group
United Kingdom
$341K +$16.5K +1,020 +6%

SMMT Hedge Fund Activity: Q1 2026 in Review

222 of the 8,126 institutional investors tracked by Wall St. Rank reported a position in Summit Therapeutics (SMMT) for Q1 2026, worth a combined $2.25B — up 9.3% from $2.06B a quarter earlier.

Buyers outnumbered sellers: 58 funds opened new SMMT positions and 37 closed out — a net gain of 21 holders — while 83 added to existing stakes and 49 trimmed.

The largest buyer was UBS Group, adding an estimated $45.4M. The largest seller was Fidelity Investments, cutting an estimated $40.6M.

  • 222 institutional investors held Summit Therapeutics (SMMT) as of Q1 2026, up from 206 in Q4 2025.
  • Funds reported $2.25B of Summit Therapeutics stock for Q1 2026, up 9.3% quarter-over-quarter.
  • 58 funds opened new Summit Therapeutics positions in Q1 2026 and 37 closed out, a net change of +21 holders.
  • The largest Summit Therapeutics buyer in Q1 2026 was UBS Group, an estimated $45.4M added.
  • The largest Summit Therapeutics seller in Q1 2026 was Fidelity Investments, an estimated $40.6M sold.

Based on aggregated 13F filings for Q1 2026.