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Summit Therapeutics
SMMT

222 hedge funds and large institutions have $2.25B invested in Summit Therapeutics in 2026 Q1 according to their latest regulatory filings, with 58 funds opening new positions, 83 increasing their positions, 49 reducing their positions, and 37 closing their positions.

New
Increased
Maintained
Reduced
Closed

69% more repeat investments, than reductions

Existing positions increased: 83 | Existing positions reduced: 49

57% more first-time investments, than exits

New positions opened: 58 | Existing positions closed: 37

9% more capital invested

Capital invested by funds: $2.06B → $2.25B (+$192M)

8% more funds holding

Funds holding: 206 → 222 (+16)

0.06% more ownership

Funds ownership: 15.27% → 15.34% (+0.06%)

0% more funds holding in top 10

Funds holding in top 10: 3 → 3 (0)

15% less call options, than puts

Call options by funds: $39.9M | Put options by funds: $46.7M

Holders
222
Holders Change
+16
Holders Change %
+7.77%
% of All Funds
2.73%
Holding in Top 10
3
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.04%
New
58
Increased
83
Reduced
49
Closed
37
Calls
$39.9M
Puts
$46.7M
Net Calls
-$6.79M
Net Calls Change
+$13.4M

Top Buyers

1
UBS Group
UBS Group
Switzerland
+$45.4M
2
D.E. Shaw & Co
D.E. Shaw & Co
New York
+$29.5M
3
SCM
Superstring Capital Management
New York
+$14.4M
4
Point72 Asset Management
Point72 Asset Management
Connecticut
+$12.7M
5
Morgan Stanley
Morgan Stanley
New York
+$11.7M

Top Sellers

1
Fidelity Investments
Fidelity Investments
Massachusetts
-$40.6M
2
Citadel Advisors
Citadel Advisors
Florida
-$32.9M
3
PCMH
Polymer Capital Management (HK)
Hong Kong
-$20.8M
4
T. Rowe Price Associates
T. Rowe Price Associates
Maryland
-$17.7M
5
SC
Sculptor Capital
New York
-$6.24M
Name Holding Trade Value Shares
Change 		Change in
Stake
RhumbLine Advisers
51
RhumbLine Advisers
Massachusetts
$2.46M +$133K +8,201 +7%
Millennium Management
52
Millennium Management
New York
$2.39M -$5.54M -342,744 -73%
TI
53
Tidal Investments
Wisconsin
$2.28M +$1.95M +120,314 New
Wells Fargo
54
Wells Fargo
California
$2.28M -$171K -10,585 -8%
YIH
55
Y-Intercept (HK)
Hong Kong
$2.27M +$1.94M +119,655 New
TE
56
Tema ETFs
New York
$2.27M +$384K +23,749 +25%
JF
57
Jump Financial
Illinois
$2.19M +$1.87M +115,738 New
Cerity Partners
58
Cerity Partners
New York
$2.16M +$14.7K +908 +0.8%
PA
59
Profund Advisors
Maryland
$2.14M +$148K +9,165 +9%
IMRF
60
Illinois Municipal Retirement Fund
Illinois
$2.12M +$203K +12,527 +13%
Bank of Montreal
61
Bank of Montreal
Ontario, Canada
$2.05M +$204K +12,588 +13%
JFG
62
Jefferies Financial Group
New York
$1.9M – – –
State Board of Administration of Florida Retirement System
63
State Board of Administration of Florida Retirement System
Florida
$1.82M – – –
BPA
64
Beacon Pointe Advisors
California
$1.79M +$886K +54,783 +138%
ACM
65
ADAR1 Capital Management
Texas
$1.74M – – –
Canada Pension Plan Investment Board
66
Canada Pension Plan Investment Board
Ontario, Canada
$1.73M +$1.47M +91,000 New
NCM
67
NEXTBio Capital Management
California
$1.7M +$1.45M +89,717 New
Dimensional Fund Advisors
68
Dimensional Fund Advisors
Texas
$1.67M -$4.66M -288,067 -76%
Focus Partners Wealth
69
Focus Partners Wealth
Massachusetts
$1.59M -$73.2K -4,528 -5%
DFCM
70
Dark Forest Capital Management
Puerto Rico
$1.53M -$102K -6,289 -7%
UBS AM
71
UBS AM
Illinois
$1.51M +$1.13K +70 +0.1%
QCM
72
Quantinno Capital Management
New York
$1.4M +$962K +59,512 +415%
SAM
73
Sectoral Asset Management
Quebec, Canada
$1.4M -$162K -10,010 -13%
GC
74
Guggenheim Capital
Illinois
$1.26M +$269K +16,604 +33%
WMP
75
Wealth Management Partners
Arizona
$1.21M +$70.4K +4,354 +7%
1 2
3
4 5

SMMT Hedge Fund Activity: Q1 2026 in Review

222 of the 8,126 institutional investors tracked by Wall St. Rank reported a position in Summit Therapeutics (SMMT) for Q1 2026, worth a combined $2.25B — up 9.3% from $2.06B a quarter earlier.

Buyers outnumbered sellers: 58 funds opened new SMMT positions and 37 closed out — a net gain of 21 holders — while 83 added to existing stakes and 49 trimmed.

The largest buyer was UBS Group, adding an estimated $45.4M. The largest seller was Fidelity Investments, cutting an estimated $40.6M.

  • 222 institutional investors held Summit Therapeutics (SMMT) as of Q1 2026, up from 206 in Q4 2025.
  • Funds reported $2.25B of Summit Therapeutics stock for Q1 2026, up 9.3% quarter-over-quarter.
  • 58 funds opened new Summit Therapeutics positions in Q1 2026 and 37 closed out, a net change of +21 holders.
  • The largest Summit Therapeutics buyer in Q1 2026 was UBS Group, an estimated $45.4M added.
  • The largest Summit Therapeutics seller in Q1 2026 was Fidelity Investments, an estimated $40.6M sold.

Based on aggregated 13F filings for Q1 2026.