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Summit Therapeutics

238 hedge funds and large institutions have $2.08B invested in Summit Therapeutics in 2025 Q2 according to their latest regulatory filings, with 73 funds opening new positions, 66 increasing their positions, 75 reducing their positions, and 45 closing their positions.

New
Increased
Maintained
Reduced
Closed

64% more call options, than puts

Call options by funds: $126M | Put options by funds: $77.1M

62% more first-time investments, than exits

New positions opened: 73 | Existing positions closed: 45

33% more funds holding in top 10

Funds holding in top 10: 34 (+1)

12% more funds holding

Funds holding: 212238 (+26)

9% more capital invested

Capital invested by funds: $1.91B → $2.08B (+$173M)

0.21% less ownership

Funds ownership: 13.39%13.18% (-0.21%)

12% less repeat investments, than reductions

Existing positions increased: 66 | Existing positions reduced: 75

Holders
238
Holders Change
+26
Holders Change %
+12.26%
% of All Funds
3.13%
Holding in Top 10
4
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+33.33%
% of All Funds
0.05%
New
73
Increased
66
Reduced
75
Closed
45
Calls
$126M
Puts
$77.1M
Net Calls
+$49.1M
Net Calls Change
+$69.3M
Name Holding Trade Value Shares
Change
Change in
Stake
BBA
1
Baker Bros. Advisors
New York
$718M +$212M +9,298,109 +38%
Fidelity Investments
2
Fidelity Investments
Massachusetts
$196M -$2.55M -111,847 -1%
Vanguard Group
3
Vanguard Group
Pennsylvania
$185M -$67.7M -2,966,835 -25%
BlackRock
4
BlackRock
New York
$146M -$35.4M -1,550,889 -18%
State Street
5
State Street
Massachusetts
$85.5M -$19M -833,691 -17%
T. Rowe Price Associates
6
T. Rowe Price Associates
Maryland
$83.1M -$60.5M -2,652,656 -40%
Geode Capital Management
7
Geode Capital Management
Massachusetts
$62.5M -$7.98M -350,067 -11%
Pictet Asset Management
8
Pictet Asset Management
Switzerland
$45.6M -$11.4M -497,731 -19%
UBS Group
9
UBS Group
Switzerland
$44.6M +$18.9M +829,735 +66%
Norges Bank
10
Norges Bank
Norway
$29.6M +$8.48M +371,888 +37%
Charles Schwab
11
Charles Schwab
California
$27.5M -$3.85M -169,046 -12%
Aberdeen Group
12
Aberdeen Group
United Kingdom
$24.2M -$1.4M -61,280 -5%
ACL
13
APEIRON Capital Ltd
Hong Kong
$23.2M +$27.4M +1,200,941 New
PCH
14
Polar Capital Holdings
United Kingdom
$21.3M +$22.8M +1,000,000 New
PCMH
15
Polymer Capital Management (HK)
Hong Kong
$18.9M +$11.3M +493,854 +125%
Fiera Capital (Canada)
16
Fiera Capital (Canada)
Quebec, Canada
$16.7M +$17.9M +782,847 New
RSCM
17
Rock Springs Capital Management
Maryland
$15.1M -$6.5M -285,000 -29%
Morgan Stanley
18
Morgan Stanley
New York
$13.7M +$3.74M +163,875 +34%
Bank of America
19
Bank of America
North Carolina
$12M +$4.49M +196,925 +53%
Millennium Management
20
Millennium Management
New York
$11.8M -$7.55M -331,000 -37%
Northern Trust
21
Northern Trust
Illinois
$11.3M -$7.12M -312,022 -37%
CS
22
Candriam SCA
Luxembourg
$10.9M -$7.41M -324,755 -39%
TD Asset Management
23
TD Asset Management
Ontario, Canada
$10.3M -$7.37M -323,180 -40%
Invesco
24
Invesco
Georgia
$9.02M +$783K +34,322 +9%
RT
25
Rockland Trust
Massachusetts
$8.51M +$9.12M +400,000 New

SMMT Hedge Fund Activity: Q2 2025 in Review

238 of the 7,595 institutional investors tracked by Wall St. Rank reported a position in Summit Therapeutics (SMMT) for Q2 2025, worth a combined $2.08B — up 9.1% from $1.91B a quarter earlier.

Buyers outnumbered sellers: 73 funds opened new SMMT positions and 45 closed out — a net gain of 28 holders — while 66 added to existing stakes and 75 trimmed.

The largest buyer was Baker Bros. Advisors, adding an estimated $212M. The largest seller was Vanguard Group, cutting an estimated $67.7M.

  • 238 institutional investors held Summit Therapeutics (SMMT) as of Q2 2025, up from 212 in Q1 2025.
  • Funds reported $2.08B of Summit Therapeutics stock for Q2 2025, up 9.1% quarter-over-quarter.
  • 73 funds opened new Summit Therapeutics positions in Q2 2025 and 45 closed out, a net change of +28 holders.
  • The largest Summit Therapeutics buyer in Q2 2025 was Baker Bros. Advisors, an estimated $212M added.
  • The largest Summit Therapeutics seller in Q2 2025 was Vanguard Group, an estimated $67.7M sold.

Based on aggregated 13F filings for Q2 2025.