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Summit Therapeutics

222 hedge funds and large institutions have $2.25B invested in Summit Therapeutics in 2026 Q1 according to their latest regulatory filings, with 58 funds opening new positions, 83 increasing their positions, 49 reducing their positions, and 37 closing their positions.

New
Increased
Maintained
Reduced
Closed

69% more repeat investments, than reductions

Existing positions increased: 83 | Existing positions reduced: 49

57% more first-time investments, than exits

New positions opened: 58 | Existing positions closed: 37

9% more capital invested

Capital invested by funds: $2.06B → $2.25B (+$192M)

8% more funds holding

Funds holding: 206222 (+16)

0.06% more ownership

Funds ownership: 15.27%15.34% (+0.06%)

0% more funds holding in top 10

Funds holding in top 10: 33 (0)

15% less call options, than puts

Call options by funds: $39.9M | Put options by funds: $46.7M

Holders
222
Holders Change
+16
Holders Change %
+7.77%
% of All Funds
2.73%
Holding in Top 10
3
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.04%
New
58
Increased
83
Reduced
49
Closed
37
Calls
$39.9M
Puts
$46.7M
Net Calls
-$6.79M
Net Calls Change
+$13.4M
Name Holding Trade Value Shares
Change
Change in
Stake
BBA
1
Baker Bros. Advisors
New York
$690M
Fidelity Investments
2
Fidelity Investments
Massachusetts
$206M -$40.6M -2,507,608 -19%
BlackRock
3
BlackRock
New York
$183M +$4.72M +291,837 +3%
T. Rowe Price Associates
4
T. Rowe Price Associates
Maryland
$157M -$17.7M -1,093,556 -12%
State Street
5
State Street
Massachusetts
$133M +$6.34M +391,799 +6%
VCM
6
Vanguard Capital Management
Pennsylvania
$108M +$92.4M +5,711,802 New
VPM
7
Vanguard Portfolio Management
Pennsylvania
$99.2M +$84.6M +5,233,252 New
UBS Group
8
UBS Group
Switzerland
$69.8M +$45.4M +2,809,596 +323%
Geode Capital Management
9
Geode Capital Management
Massachusetts
$62.9M +$2.72M +168,374 +5%
D.E. Shaw & Co
10
D.E. Shaw & Co
New York
$42.5M +$29.5M +1,826,945 +440%
Morgan Stanley
11
Morgan Stanley
New York
$31.3M +$11.7M +724,012 +78%
ACL
12
APEIRON Capital Ltd
Hong Kong
$24.8M -$1.62K -100 -0%
Pictet Asset Management
13
Pictet Asset Management
Switzerland
$24M -$980K -60,596 -4%
Two Sigma Investments
14
Two Sigma Investments
New York
$18.6M +$6.52M +402,937 +70%
Charles Schwab
15
Charles Schwab
California
$18.2M +$1.1M +68,238 +8%
TD Asset Management
16
TD Asset Management
Ontario, Canada
$18.1M -$4.02M -248,378 -21%
VFT
17
Vanguard Fiduciary Trust
Pennsylvania
$17.7M +$15.1M +934,394 New
SCM
18
Superstring Capital Management
New York
$16.9M +$14.4M +892,873 New
Point72 Asset Management
19
Point72 Asset Management
Connecticut
$14.9M +$12.7M +784,186 New
RSCM
20
Rock Springs Capital Management
Maryland
$13.5M
Aberdeen Group
21
Aberdeen Group
United Kingdom
$12.6M -$4.23M -261,807 -28%
Squarepoint
22
Squarepoint
New York
$11.6M -$1.64M -101,533 -14%
Susquehanna International Group
23
Susquehanna International Group
Pennsylvania
$11.5M +$9.77M +603,933 New
Bank of America
24
Bank of America
North Carolina
$11.4M +$1.96M +121,299 +25%
Manulife (Manufacturers Life Insurance)
25
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$11.2M +$2.46M +151,857 +34%

SMMT Hedge Fund Activity: Q1 2026 in Review

222 of the 8,126 institutional investors tracked by Wall St. Rank reported a position in Summit Therapeutics (SMMT) for Q1 2026, worth a combined $2.25B — up 9.3% from $2.06B a quarter earlier.

Buyers outnumbered sellers: 58 funds opened new SMMT positions and 37 closed out — a net gain of 21 holders — while 83 added to existing stakes and 49 trimmed.

The largest buyer was UBS Group, adding an estimated $45.4M. The largest seller was Fidelity Investments, cutting an estimated $40.6M.

  • 222 institutional investors held Summit Therapeutics (SMMT) as of Q1 2026, up from 206 in Q4 2025.
  • Funds reported $2.25B of Summit Therapeutics stock for Q1 2026, up 9.3% quarter-over-quarter.
  • 58 funds opened new Summit Therapeutics positions in Q1 2026 and 37 closed out, a net change of +21 holders.
  • The largest Summit Therapeutics buyer in Q1 2026 was UBS Group, an estimated $45.4M added.
  • The largest Summit Therapeutics seller in Q1 2026 was Fidelity Investments, an estimated $40.6M sold.

Based on aggregated 13F filings for Q1 2026.