Two Sigma Investments
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Two Sigma Investments’s Summit Therapeutics SMMT Stock Holding History

Two Sigma Investments’s Portfolio SMMT Stock Details SMMT Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$18.6M Buy
981,185
+402,937
+70% +$6.52M 0.02% 991
2025
Q4 		$10.1M Buy
578,248
+553,218
+2,210% +$10.4M 0.01% 1116
2025
Q3 		$517K Buy
+25,030
New +$607K ﹤0.01% 2965
2024
Q2 		– Sell
-23,579
Closed -$97.6K – 3301
2024
Q1 		$97.6K Sell
23,579
-82,600
-78% -$328K ﹤0.01% 2835
2023
Q4 		$277K Hold
106,179
– – ﹤0.01% 2722
2023
Q3 		$199K Sell
106,179
-75,800
-42% -$145K ﹤0.01% 2643
2023
Q2 		$457K Sell
181,979
-333,959
-65% -$609K ﹤0.01% 2368
2023
Q1 		$903K Buy
515,938
+229,738
+80% +$627K ﹤0.01% 1928
2022
Q4 		$1.22M Buy
+286,200
New +$521K ﹤0.01% 1601

Other funds holding SMMT

BBA
Baker Bros. Advisors New York $17.4B AUM 131.5% 1-Year Est. Return
Fidelity Investments
Fidelity Investments Boston, Massachusetts $1.9T AUM 41.92% 1-Year Est. Return
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
T. Rowe Price Associates
T. Rowe Price Associates Baltimore, Maryland $865B AUM 30.76% 1-Year Est. Return
State Street
State Street Boston, Massachusetts $2.9T AUM 29.55% 1-Year Est. Return
VCM
Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM
VPM
Vanguard Portfolio Management Malvern, Pennsylvania $1.91T AUM
UBS Group
UBS Group Zurich, Switzerland $666B AUM 30.12% 1-Year Est. Return
Geode Capital Management
Geode Capital Management Boston, Massachusetts $1.61T AUM 30.72% 1-Year Est. Return
D.E. Shaw & Co
D.E. Shaw & Co New York $166B AUM 43.98% 1-Year Est. Return

Two Sigma Investments's SMMT Position: Q1 2026 in Review

Two Sigma Investments increased its Summit Therapeutics (SMMT) stake by 70% in Q1 2026, buying an estimated $6.52M and bringing the position to 981,185 shares worth $18.6M. The position accounts for 0.02% of the portfolio, ranked #991.

Two Sigma Investments first reported a position in SMMT in Q4 2022 and has held it in 9 quarters since. 222 funds tracked by Wall St. Rank hold SMMT as of Q1 2026.

  • Two Sigma Investments held 981,185 shares of Summit Therapeutics worth $18.6M as of Q1 2026.
  • Two Sigma Investments bought 402,937 Summit Therapeutics shares in Q1 2026, an estimated $6.52M.
  • Summit Therapeutics made up 0.02% of Two Sigma Investments's portfolio in Q1 2026, its #991 holding.
  • Two Sigma Investments first reported a position in Summit Therapeutics in Q4 2022 and has held it in 9 quarters since.
  • 222 funds tracked by Wall St. Rank held Summit Therapeutics as of Q1 2026.

Based on Two Sigma Investments's 13F filing for Q1 2026, filed 15 May 2026.