Schrodinger
SDGR
222 hedge funds and large institutions have $1.24B invested in Schrodinger in 2025 Q4 according to their latest regulatory filings, with 27 funds opening new positions, 77 increasing their positions, 79 reducing their positions, and 30 closing their positions.
425% more call options, than puts
Call options by funds: $41.5M | Put options by funds: $7.89M
0.16% less ownership
Funds ownership: 108.02% → 107.86% (-0.16%)
3% less repeat investments, than reductions
Existing positions increased: 77 | Existing positions reduced: 79
1% less funds holding
Funds holding: 225 → 222 (-3)
10% less first-time investments, than exits
New positions opened: 27 | Existing positions closed: 30
11% less capital invested
Capital invested by funds: $1.4B → $1.24B (-$152M)
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
UBS Group
Zurich,
Switzerland
|
+$9.27M |
| 2 |
UBS AM
Chicago,
Illinois
|
+$7.85M |
| 3 |
Man Group
London,
United Kingdom
|
+$5.27M |
| 4 |
Allianz Asset Management
Munich,
Germany
|
+$4.7M |
| 5 |
AIM
ARK Investment Management
St. Petersburg,
Florida
|
+$4.53M |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
RCMNY
Rubric Capital Management (New York)
New York
|
-$20.8M |
| 2 |
Millennium Management
New York
|
-$10.9M |
| 3 |
Morgan Stanley
New York
|
-$10.4M |
| 4 |
Royal Bank of Canada
Toronto,
Ontario, Canada
|
-$7.15M |
| 5 |
Two Sigma Investments
New York
|
-$6.72M |
SDGR Hedge Fund Activity: Q4 2025 in Review
222 of the 8,267 institutional investors tracked by Wall St. Rank reported a position in Schrodinger (SDGR) for Q4 2025, worth a combined $1.24B — down 11% from $1.4B a quarter earlier.
Sellers outnumbered buyers: 30 funds closed out of SDGR and 27 opened new positions — a net loss of 3 holders — while 79 trimmed existing stakes and 77 added.
The largest buyer was UBS Group, adding an estimated $9.27M. The largest seller was Rubric Capital Management (New York), cutting an estimated $20.8M.
- 222 institutional investors held Schrodinger (SDGR) as of Q4 2025, down from 225 in Q3 2025.
- Funds reported $1.24B of Schrodinger stock for Q4 2025, down 11% quarter-over-quarter.
- 27 funds opened new Schrodinger positions in Q4 2025 and 30 closed out, a net change of -3 holders.
- The largest Schrodinger buyer in Q4 2025 was UBS Group, an estimated $9.27M added.
- The largest Schrodinger seller in Q4 2025 was Rubric Capital Management (New York), an estimated $20.8M sold.
Based on aggregated 13F filings for Q4 2025.