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Schrodinger

227 hedge funds and large institutions have $748M invested in Schrodinger in 2026 Q1 according to their latest regulatory filings, with 51 funds opening new positions, 80 increasing their positions, 57 reducing their positions, and 41 closing their positions.

New
Increased
Maintained
Reduced
Closed

40% more repeat investments, than reductions

Existing positions increased: 80 | Existing positions reduced: 57

24% more first-time investments, than exits

New positions opened: 51 | Existing positions closed: 41

3% more funds holding

Funds holding: 221227 (+6)

7% less call options, than puts

Call options by funds: $6.38M | Put options by funds: $6.87M

6.02% less ownership

Funds ownership: 107.85%101.83% (-6%)

40% less capital invested

Capital invested by funds: $1.24B → $748M (-$495M)

Holders
227
Holders Change
+6
Holders Change %
+2.71%
% of All Funds
2.79%
Holding in Top 10
1
Holding in Top 10 Change
+1
Holding in Top 10 Change %
% of All Funds
0.01%
New
51
Increased
80
Reduced
57
Closed
41
Calls
$6.38M
Puts
$6.87M
Net Calls
-$496K
Net Calls Change
-$34.1M
Name Holding Trade Value Shares
Change
Change in
Stake
BlackRock
1
BlackRock
New York
$110M +$2.23M +161,464 +2%
Gates Foundation Trust
2
Gates Foundation Trust
Washington
$79.3M
RCMNY
3
Rubric Capital Management (New York)
New York
$68.2M +$25.3M +1,828,502 +44%
VPM
4
Vanguard Portfolio Management
Pennsylvania
$43.9M +$53.4M +3,862,197 New
Sumitomo Mitsui Trust Group
5
Sumitomo Mitsui Trust Group
Japan
$36.2M -$21.1M -1,523,930 -32%
NAMA
6
Nikko Asset Management Americas
New York
$36.2M +$5.13M +371,167 +13%
Massachusetts Financial Services
7
Massachusetts Financial Services
Massachusetts
$30.5M +$5.44M +393,343 +17%
UBS AM
8
UBS AM
Illinois
$30.2M -$14.6M -1,057,607 -28%
VCM
9
Vanguard Capital Management
Pennsylvania
$29.6M +$36M +2,604,374 New
State Street
10
State Street
Massachusetts
$24.9M +$823K +59,521 +3%
AIM
11
ARK Investment Management
Florida
$23.5M -$618K -44,694 -2%
Morgan Stanley
12
Morgan Stanley
New York
$15.6M +$2.55M +184,501 +16%
Geode Capital Management
13
Geode Capital Management
Massachusetts
$15.4M -$460K -33,292 -2%
UBS Group
14
UBS Group
Switzerland
$15M -$1.7M -122,747 -9%
Dimensional Fund Advisors
15
Dimensional Fund Advisors
Texas
$10M -$1.78M -128,983 -13%
Baillie Gifford & Co
16
Baillie Gifford & Co
United Kingdom
$9.1M -$474K -34,318 -4%
Goldman Sachs
17
Goldman Sachs
New York
$8.55M +$1.15M +83,155 +12%
Man Group
18
Man Group
United Kingdom
$7.74M +$3.31M +239,740 +54%
Northern Trust
19
Northern Trust
Illinois
$6.51M +$246K +17,769 +3%
Tudor Investment Corp
20
Tudor Investment Corp
Connecticut
$6.25M +$1.54M +111,615 +25%
PM
21
Prosight Management
Texas
$5.8M +$7.06M +510,578 New
Charles Schwab
22
Charles Schwab
California
$5.79M -$85.2K -6,161 -1%
HF
23
HRT Financial
New York
$5.48M +$4.4M +318,083 +193%
AG
24
Algert Global
California
$5.41M +$3.65M +264,381 +125%
AQR Capital Management
25
AQR Capital Management
Connecticut
$5.05M +$3.9M +282,437 +175%

SDGR Hedge Fund Activity: Q1 2026 in Review

227 of the 8,126 institutional investors tracked by Wall St. Rank reported a position in Schrodinger (SDGR) for Q1 2026, worth a combined $748M — down 40% from $1.24B a quarter earlier.

Buyers outnumbered sellers: 51 funds opened new SDGR positions and 41 closed out — a net gain of 10 holders — while 80 added to existing stakes and 57 trimmed.

The largest buyer was Rubric Capital Management (New York), adding an estimated $25.3M. The largest seller was Stephens Investment Management Group, exiting entirely with an estimated $40.2M sold.

  • 227 institutional investors held Schrodinger (SDGR) as of Q1 2026, up from 221 in Q4 2025.
  • Funds reported $748M of Schrodinger stock for Q1 2026, down 40% quarter-over-quarter.
  • 51 funds opened new Schrodinger positions in Q1 2026 and 41 closed out, a net change of +10 holders.
  • The largest Schrodinger buyer in Q1 2026 was Rubric Capital Management (New York), an estimated $25.3M added.
  • The largest Schrodinger seller in Q1 2026 was Stephens Investment Management Group, an estimated $40.2M sold.

Based on aggregated 13F filings for Q1 2026.