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Schrodinger

232 hedge funds and large institutions have $1.43B invested in Schrodinger in 2025 Q2 according to their latest regulatory filings, with 44 funds opening new positions, 79 increasing their positions, 77 reducing their positions, and 27 closing their positions.

New
Increased
Maintained
Reduced
Closed

507% more call options, than puts

Call options by funds: $34.7M | Put options by funds: $5.72M

63% more first-time investments, than exits

New positions opened: 44 | Existing positions closed: 27

9% more capital invested

Capital invested by funds: $1.31B → $1.43B (+$120M)

7% more funds holding

Funds holding: 217232 (+15)

6.8% more ownership

Funds ownership: 103.6%110.4% (+6.8%)

3% more repeat investments, than reductions

Existing positions increased: 79 | Existing positions reduced: 77

Holders
232
Holders Change
+15
Holders Change %
+6.91%
% of All Funds
3.05%
Holding in Top 10
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
44
Increased
79
Reduced
77
Closed
27
Calls
$34.7M
Puts
$5.72M
Net Calls
+$29M
Net Calls Change
+$18.8M
Name Holding Trade Value Shares
Change
Change in
Stake
BlackRock
1
BlackRock
New York
$197M +$30M +1,313,367 +16%
Gates Foundation Trust
2
Gates Foundation Trust
Washington
$140M
Vanguard Group
3
Vanguard Group
Pennsylvania
$133M +$1.66M +72,804 +1%
RCMNY
4
Rubric Capital Management (New York)
New York
$101M +$4.57M +200,000 +4%
Sumitomo Mitsui Trust Group
5
Sumitomo Mitsui Trust Group
Japan
$73.4M +$4.28M +187,535 +5%
UBS AM
6
UBS AM
Illinois
$68.7M -$21.5M -942,252 -22%
CCM
7
Cadian Capital Management
New York
$61.3M +$44.3M +1,940,952 +176%
NAMA
8
Nikko Asset Management Americas
New York
$52.1M +$3.99M +174,684 +7%
SIMG
9
Stephens Investment Management Group
Texas
$45.5M +$6.65M +291,393 +15%
State Street
10
State Street
Massachusetts
$44M -$598K -26,188 -1%
AIM
11
ARK Investment Management
Florida
$39.4M -$7.65M -335,258 -15%
Massachusetts Financial Services
12
Massachusetts Financial Services
Massachusetts
$30.1M -$13.7M -598,551 -29%
Lazard Asset Management
13
Lazard Asset Management
New York
$28.6M -$4.54M -198,955 -12%
Geode Capital Management
14
Geode Capital Management
Massachusetts
$27.4M +$415K +18,156 +1%
UBS Group
15
UBS Group
Switzerland
$27M +$21.2M +929,034 +226%
Morgan Stanley
16
Morgan Stanley
New York
$23.2M -$471K -20,641 -2%
FCM
17
Farallon Capital Management
California
$22.3M +$25.3M +1,106,000 New
American Century Companies
18
American Century Companies
Missouri
$21.9M +$1.92M +84,172 +8%
Baillie Gifford & Co
19
Baillie Gifford & Co
United Kingdom
$19.8M -$209K -9,159 -0.9%
Two Sigma Investments
20
Two Sigma Investments
New York
$16.5M +$13.2M +578,727 +239%
Dimensional Fund Advisors
21
Dimensional Fund Advisors
Texas
$14.9M -$814K -35,650 -5%
Two Sigma Advisers
22
Two Sigma Advisers
New York
$14.5M +$13.6M +596,800 +473%
Northern Trust
23
Northern Trust
Illinois
$12.4M +$713K +31,212 +5%
Bank of America
24
Bank of America
North Carolina
$12.2M +$11.2M +492,032 +428%
PHP
25
Parkman Healthcare Partners
Connecticut
$11.8M +$2.42M +106,086 +22%

SDGR Hedge Fund Activity: Q2 2025 in Review

232 of the 7,595 institutional investors tracked by Wall St. Rank reported a position in Schrodinger (SDGR) for Q2 2025, worth a combined $1.43B — up 9.2% from $1.31B a quarter earlier.

Buyers outnumbered sellers: 44 funds opened new SDGR positions and 27 closed out — a net gain of 17 holders — while 79 added to existing stakes and 77 trimmed.

The largest buyer was Cadian Capital Management, adding an estimated $44.3M. The largest seller was UBS AM, cutting an estimated $21.5M.

  • 232 institutional investors held Schrodinger (SDGR) as of Q2 2025, up from 217 in Q1 2025.
  • Funds reported $1.43B of Schrodinger stock for Q2 2025, up 9.2% quarter-over-quarter.
  • 44 funds opened new Schrodinger positions in Q2 2025 and 27 closed out, a net change of +17 holders.
  • The largest Schrodinger buyer in Q2 2025 was Cadian Capital Management, an estimated $44.3M added.
  • The largest Schrodinger seller in Q2 2025 was UBS AM, an estimated $21.5M sold.

Based on aggregated 13F filings for Q2 2025.