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Schrodinger
SDGR

232 hedge funds and large institutions have $1.43B invested in Schrodinger in 2025 Q2 according to their latest regulatory filings, with 44 funds opening new positions, 79 increasing their positions, 77 reducing their positions, and 27 closing their positions.

New
Increased
Maintained
Reduced
Closed

507% more call options, than puts

Call options by funds: $34.7M | Put options by funds: $5.72M

63% more first-time investments, than exits

New positions opened: 44 | Existing positions closed: 27

9% more capital invested

Capital invested by funds: $1.31B → $1.43B (+$120M)

7% more funds holding

Funds holding: 217 → 232 (+15)

6.8% more ownership

Funds ownership: 103.6% → 110.4% (+6.8%)

3% more repeat investments, than reductions

Existing positions increased: 79 | Existing positions reduced: 77

Holders
232
Holders Change
+15
Holders Change %
+6.91%
% of All Funds
3.05%
Holding in Top 10
–
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
–
New
44
Increased
79
Reduced
77
Closed
27
Calls
$34.7M
Puts
$5.72M
Net Calls
+$29M
Net Calls Change
+$18.8M

Top Buyers

Rank Fund Capital Flow
1
CCM
Cadian Capital Management
New York
+$44.3M
2
BlackRock
BlackRock
New York
+$30M
3
FCM
Farallon Capital Management
California
+$25.3M
4
UBS Group
UBS Group
Switzerland
+$21.2M
5
Two Sigma Advisers
Two Sigma Advisers
New York
+$13.6M

Top Sellers

Rank Fund Capital Flow
1
UBS AM
UBS AM
Illinois
-$21.5M
2
TAM
Tocqueville Asset Management
New York
-$16.7M
3
Massachusetts Financial Services
Massachusetts Financial Services
Massachusetts
-$13.7M
4
Citadel Advisors
Citadel Advisors
Florida
-$8.49M
5
Millennium Management
Millennium Management
New York
-$8.39M
Name Holding Trade Value Shares
Change 		Change in
Stake
Northwestern Mutual Wealth Management
201
Northwestern Mutual Wealth Management
Wisconsin
$2.82K +$2.06K +90 +180%
S
202
SignatureFD
Georgia
$2.78K -$2.88K -126 -48%
SCM
203
Sterling Capital Management
North Carolina
$2.74K +$1.8K +79 +139%
SPIA
204
Steward Partners Investment Advisory
New York
$2.68K -$1.48K -65 -33%
SAM
205
Smartleaf Asset Management
Massachusetts
$2.54K -$12.6K -552 -82%
PA
206
Parallel Advisors
California
$1.85K -$434 -19 -17%
PS
207
Principal Securities
Iowa
$1.77K +$525 +23 +35%
LFG
208
Larson Financial Group
Missouri
$1.71K -$13.2K -579 -87%
RIL
209
Rothschild Investment LLC
Illinois
$1.61K -$799 -35 -30%
IA
210
IFP Advisors
Florida
$1.45K -$1.1K -48 -48%
PWMG
211
Prestige Wealth Management Group
New Jersey
$1.17K -$91 -4 -6%
RBC
212
Roble Belko & Company
Pennsylvania
$1K – – –
HFS
213
Hantz Financial Services
Michigan
$1K +$753 +33 +300%
OP
214
ORG Partners
Indiana
$927 +$571 +25 +125%
AAP
215
Arax Advisory Partners
Colorado
$886 – – –
BTI
216
Blue Trust Inc
Georgia
$885 -$11.7K -511 -92%
VFM
217
Vision Financial Markets
Connecticut
$805 – – –
LSA
218
Leonteq Securities AG
Switzerland
$724 – – –
CFS
219
Compass Financial Services
Iowa
$563 – – –
FMII
220
Farmers & Merchants Investments Inc
Nebraska
$503 – – –
GWP
221
Gen-Wealth Partners
Michigan
$463 – – –
PWMG
222
Private Wealth Management Group
New Jersey
$463 – – –
CT
223
Clearstead Trust
Maine
$403 +$457 +20 New
NSIM
224
North Star Investment Management
Illinois
$322 – – –
MAWAG
225
Mid-American Wealth Advisory Group
Missouri
$322 +$365 +16 New
7 8
9
10 11

SDGR Hedge Fund Activity: Q2 2025 in Review

232 of the 7,595 institutional investors tracked by Wall St. Rank reported a position in Schrodinger (SDGR) for Q2 2025, worth a combined $1.43B — up 9.2% from $1.31B a quarter earlier.

Buyers outnumbered sellers: 44 funds opened new SDGR positions and 27 closed out — a net gain of 17 holders — while 79 added to existing stakes and 77 trimmed.

The largest buyer was Cadian Capital Management, adding an estimated $44.3M. The largest seller was UBS AM, cutting an estimated $21.5M.

  • 232 institutional investors held Schrodinger (SDGR) as of Q2 2025, up from 217 in Q1 2025.
  • Funds reported $1.43B of Schrodinger stock for Q2 2025, up 9.2% quarter-over-quarter.
  • 44 funds opened new Schrodinger positions in Q2 2025 and 27 closed out, a net change of +17 holders.
  • The largest Schrodinger buyer in Q2 2025 was Cadian Capital Management, an estimated $44.3M added.
  • The largest Schrodinger seller in Q2 2025 was UBS AM, an estimated $21.5M sold.

Based on aggregated 13F filings for Q2 2025.