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Schrodinger
SDGR

232 hedge funds and large institutions have $1.43B invested in Schrodinger in 2025 Q2 according to their latest regulatory filings, with 44 funds opening new positions, 79 increasing their positions, 77 reducing their positions, and 27 closing their positions.

New
Increased
Maintained
Reduced
Closed

507% more call options, than puts

Call options by funds: $34.7M | Put options by funds: $5.72M

63% more first-time investments, than exits

New positions opened: 44 | Existing positions closed: 27

9% more capital invested

Capital invested by funds: $1.31B → $1.43B (+$120M)

7% more funds holding

Funds holding: 217 → 232 (+15)

6.8% more ownership

Funds ownership: 103.6% → 110.4% (+6.8%)

3% more repeat investments, than reductions

Existing positions increased: 79 | Existing positions reduced: 77

Holders
232
Holders Change
+15
Holders Change %
+6.91%
% of All Funds
3.05%
Holding in Top 10
–
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
–
New
44
Increased
79
Reduced
77
Closed
27
Calls
$34.7M
Puts
$5.72M
Net Calls
+$29M
Net Calls Change
+$18.8M

Top Buyers

Rank Fund Capital Flow
1
CCM
Cadian Capital Management
New York
+$44.3M
2
BlackRock
BlackRock
New York
+$30M
3
FCM
Farallon Capital Management
California
+$25.3M
4
UBS Group
UBS Group
Switzerland
+$21.2M
5
Two Sigma Advisers
Two Sigma Advisers
New York
+$13.6M

Top Sellers

Rank Fund Capital Flow
1
UBS AM
UBS AM
Illinois
-$21.5M
2
TAM
Tocqueville Asset Management
New York
-$16.7M
3
Massachusetts Financial Services
Massachusetts Financial Services
Massachusetts
-$13.7M
4
Citadel Advisors
Citadel Advisors
Florida
-$8.49M
5
Millennium Management
Millennium Management
New York
-$8.39M
Name Holding Trade Value Shares
Change 		Change in
Stake
CWM
151
Connecticut Wealth Management
Connecticut
$244K +$277K +12,127 New
Natixis Advisors
152
Natixis Advisors
Massachusetts
$235K +$266K +11,658 New
Victory Capital Management
153
Victory Capital Management
Texas
$228K -$1.6K -70 -0.6%
CC
154
Corton Capital
Ontario, Canada
$220K +$250K +10,942 New
GSC
155
Ground Swell Capital
South Carolina
$219K +$249K +10,889 New
N
156
Numerai
California
$216K +$245K +10,731 New
Mariner
157
Mariner
Kansas
$215K +$7.17K +314 +3%
PIC
158
Portland Investment Counsel
Ontario, Canada
$206K +$228K +10,000 New
SI
159
Stephens Inc
Arkansas
$200K +$227K +9,950 New
Osaic Holdings
160
Osaic Holdings
Arizona
$177K -$20.1K -879 -9%
Canada Pension Plan Investment Board
161
Canada Pension Plan Investment Board
Ontario, Canada
$143K +$162K +7,100 New
SSG
162
Summit Securities Group
New York
$140K +$159K +6,962 New
Federated Hermes
163
Federated Hermes
Pennsylvania
$121K -$91.3K -4,000 -40%
Public Employees Retirement Association of Colorado
164
Public Employees Retirement Association of Colorado
Colorado
$119K – – –
Simplex Trading
165
Simplex Trading
Illinois
$112K +$128K +5,594 New
AIP
166
Ameritas Investment Partners
Nebraska
$109K – – –
GI
167
GAMMA Investing
California
$91.9K -$35.1K -1,539 -25%
CFS
168
CGC Financial Services
Oregon
$84.9K – – –
PNC Financial Services Group
169
PNC Financial Services Group
Pennsylvania
$57.4K -$2.33K -102 -3%
KBC Group
170
KBC Group
Belgium
$53K -$42.2K -1,849 -41%
SOW
171
State of Wyoming
Wyoming
$38.9K +$44.2K +1,934 New
Jones Financial Companies
172
Jones Financial Companies
Missouri
$30.4K +$15.8K +694 +89%
BC
173
Bayforest Capital
United Kingdom
$29.6K +$33.5K +1,469 New
QL
174
Quarry LP
New York
$27.8K -$7.83K -343 -20%
FFA
175
Farther Finance Advisors
California
$25.8K +$22.8K +997 +347%
5 6
7
8 9

SDGR Hedge Fund Activity: Q2 2025 in Review

232 of the 7,595 institutional investors tracked by Wall St. Rank reported a position in Schrodinger (SDGR) for Q2 2025, worth a combined $1.43B — up 9.2% from $1.31B a quarter earlier.

Buyers outnumbered sellers: 44 funds opened new SDGR positions and 27 closed out — a net gain of 17 holders — while 79 added to existing stakes and 77 trimmed.

The largest buyer was Cadian Capital Management, adding an estimated $44.3M. The largest seller was UBS AM, cutting an estimated $21.5M.

  • 232 institutional investors held Schrodinger (SDGR) as of Q2 2025, up from 217 in Q1 2025.
  • Funds reported $1.43B of Schrodinger stock for Q2 2025, up 9.2% quarter-over-quarter.
  • 44 funds opened new Schrodinger positions in Q2 2025 and 27 closed out, a net change of +17 holders.
  • The largest Schrodinger buyer in Q2 2025 was Cadian Capital Management, an estimated $44.3M added.
  • The largest Schrodinger seller in Q2 2025 was UBS AM, an estimated $21.5M sold.

Based on aggregated 13F filings for Q2 2025.