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Schrodinger
SDGR

217 hedge funds and large institutions have $1.31B invested in Schrodinger in 2025 Q1 according to their latest regulatory filings, with 30 funds opening new positions, 75 increasing their positions, 69 reducing their positions, and 22 closing their positions.

New
Increased
Maintained
Reduced
Closed

206% more call options, than puts

Call options by funds: $15.3M | Put options by funds: $5M

36% more first-time investments, than exits

New positions opened: 30 | Existing positions closed: 22

9% more capital invested

Capital invested by funds: $1.19B → $1.31B (+$113M)

6.4% more ownership

Funds ownership: 97.2% → 103.6% (+6.4%)

3% more funds holding

Funds holding: 211 → 217 (+6)

9% more repeat investments, than reductions

Existing positions increased: 75 | Existing positions reduced: 69

Holders
217
Holders Change
+6
Holders Change %
+2.84%
% of All Funds
2.91%
Holding in Top 10
–
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
–
New
30
Increased
75
Reduced
69
Closed
22
Calls
$15.3M
Puts
$5M
Net Calls
+$10.3M
Net Calls Change
+$6.94M

Top Buyers

Rank Fund Capital Flow
1
UBS AM
UBS AM
Illinois
+$61.6M
2
CCM
Cadian Capital Management
New York
+$24.9M
3
American Century Companies
American Century Companies
Missouri
+$22.6M
4
Citadel Advisors
Citadel Advisors
Florida
+$11.9M
5
SIMG
Stephens Investment Management Group
Texas
+$8.15M

Top Sellers

Rank Fund Capital Flow
1
Morgan Stanley
Morgan Stanley
New York
-$8.3M
2
PM
Prosight Management
Texas
-$7.55M
3
BlackRock
BlackRock
New York
-$7.5M
4
Millennium Management
Millennium Management
New York
-$5.9M
5
RCMNY
Rubric Capital Management (New York)
New York
-$4.5M
Name Holding Trade Value Shares
Change 		Change in
Stake
SCM
126
Superstring Capital Management
New York
$279K +$318K +14,114 New
RWMG
127
Redwood Wealth Management Group
New Jersey
$276K -$14.8K -658 -5%
KK
128
KLP Kapitalforvaltning
Norway
$270K – – –
XT
129
XTX Topco
Cayman Islands
$270K +$75.4K +3,350 +32%
TSS
130
Two Sigma Securities
New York
$268K +$305K +13,554 New
COPPSERS
131
Commonwealth of Pennsylvania Public School Employees Retirement System
Pennsylvania
$262K +$32.2K +1,431 +12%
State of Tennessee, Department of Treasury
132
State of Tennessee, Department of Treasury
Tennessee
$259K – – –
ProShare Advisors
133
ProShare Advisors
Maryland
$258K -$82.4K -3,664 -22%
Group One Trading
134
Group One Trading
Illinois
$258K -$102K -4,543 -26%
OPERF
135
Oregon Public Employees Retirement Fund
Oregon
$251K -$6.75K -300 -2%
IMC Chicago
136
IMC Chicago
Illinois
$250K -$88.3K -3,925 -24%
PAG
137
Private Advisor Group
New Jersey
$244K – – –
CWM
138
CIBC World Markets
New York
$244K +$278K +12,338 New
BHCM
139
Brevan Howard Capital Management
Jersey
$238K -$349K -15,524 -56%
Victory Capital Management
140
Victory Capital Management
Texas
$225K -$3.71K -165 -1%
PFSRSONJ
141
Police & Firemen's Retirement System of New Jersey
New Jersey
$224K – – –
Mariner
142
Mariner
Kansas
$205K +$234K +10,379 New
Federated Hermes
143
Federated Hermes
Pennsylvania
$197K +$112K +5,000 +100%
Osaic Holdings
144
Osaic Holdings
Arizona
$191K +$65.5K +2,913 +43%
TRCT
145
Tower Research Capital (TRC)
New York
$178K +$129K +5,712 +173%
SG Americas Securities
146
SG Americas Securities
New York
$169K -$110K -4,873 -36%
CUAMC
147
China Universal Asset Management Company
China
$127K – – –
GI
148
GAMMA Investing
California
$121K +$74.5K +3,313 +118%
Public Employees Retirement Association of Colorado
149
Public Employees Retirement Association of Colorado
Colorado
$116K – – –
AIP
150
Ameritas Investment Partners
Nebraska
$107K – – –
4 5
6
7 8

SDGR Hedge Fund Activity: Q1 2025 in Review

217 of the 7,458 institutional investors tracked by Wall St. Rank reported a position in Schrodinger (SDGR) for Q1 2025, worth a combined $1.31B — up 9.5% from $1.19B a quarter earlier.

Buyers outnumbered sellers: 30 funds opened new SDGR positions and 22 closed out — a net gain of 8 holders — while 75 added to existing stakes and 69 trimmed.

The largest buyer was UBS AM, adding an estimated $61.6M. The largest seller was Morgan Stanley, cutting an estimated $8.3M.

  • 217 institutional investors held Schrodinger (SDGR) as of Q1 2025, up from 211 in Q4 2024.
  • Funds reported $1.31B of Schrodinger stock for Q1 2025, up 9.5% quarter-over-quarter.
  • 30 funds opened new Schrodinger positions in Q1 2025 and 22 closed out, a net change of +8 holders.
  • The largest Schrodinger buyer in Q1 2025 was UBS AM, an estimated $61.6M added.
  • The largest Schrodinger seller in Q1 2025 was Morgan Stanley, an estimated $8.3M sold.

Based on aggregated 13F filings for Q1 2025.