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Schrodinger

221 hedge funds and large institutions have $1.24B invested in Schrodinger in 2025 Q4 according to their latest regulatory filings, with 27 funds opening new positions, 76 increasing their positions, 79 reducing their positions, and 30 closing their positions.

New
Increased
Maintained
Reduced
Closed

425% more call options, than puts

Call options by funds: $41.5M | Put options by funds: $7.89M

0.16% less ownership

Funds ownership: 108.01%107.85% (-0.16%)

4% less repeat investments, than reductions

Existing positions increased: 76 | Existing positions reduced: 79

1% less funds holding

Funds holding: 224221 (-3)

10% less first-time investments, than exits

New positions opened: 27 | Existing positions closed: 30

11% less capital invested

Capital invested by funds: $1.4B → $1.24B (-$152M)

Holders
221
Holders Change
-3
Holders Change %
-1.34%
% of All Funds
2.69%
Holding in Top 10
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
27
Increased
76
Reduced
79
Closed
30
Calls
$41.5M
Puts
$7.89M
Net Calls
+$33.6M
Net Calls Change
+$4.09M
Name Holding Trade Value Shares
Change
Change in
Stake
DekaBank Deutsche Girozentrale
101
DekaBank Deutsche Girozentrale
Germany
$538K
IMRF
102
Illinois Municipal Retirement Fund
Illinois
$532K -$28.5K -1,502 -5%
TI
103
TrueMark Investments
Illinois
$531K -$16.1K -848 -3%
RA
104
Royce & Associates
New York
$519K +$550K +29,009 New
SOADOR
105
State of Alaska Department of Revenue
Alaska
$510K +$6.86K +362 +1%
Janus Henderson Group
106
Janus Henderson Group
United Kingdom
$506K
ECSS
107
Eurizon Capital SGR SpA
$480K +$509K +26,842 New
GCP
108
GSA Capital Partners
United Kingdom
$479K +$507K +26,765 New
XT
109
XTX Topco
Cayman Islands
$474K -$513K -27,066 -51%
HCA
110
Harbor Capital Advisors
Illinois
$463K +$125K +6,601 +34%
LSERS
111
Louisiana State Employees Retirement System
Louisiana
$460K -$1.9K -100 -0.4%
Manulife (Manufacturers Life Insurance)
112
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$449K -$30.2K -1,593 -6%
CAPTRUST Financial Advisors
113
CAPTRUST Financial Advisors
North Carolina
$388K +$31.4K +1,655 +8%
HSBC Holdings
114
HSBC Holdings
United Kingdom
$378K -$554K -29,240 -58%
BM
115
Brandywine Managers
Delaware
$373K
PWM
116
Perigon Wealth Management
California
$370K +$110K +5,803 +39%
NIM
117
NEOS Investment Management
Connecticut
$364K +$67.1K +3,540 +21%
TE
118
Tema ETFs
New York
$359K +$61.4K +3,240 +19%
I
119
InceptionR
California
$353K +$374K +19,717 New
Group One Trading
120
Group One Trading
Illinois
$344K +$75.6K +3,985 +26%
ASRS
121
Arizona State Retirement System
Arizona
$320K -$20.5K -1,081 -6%
Raymond James Financial
122
Raymond James Financial
Florida
$306K -$31.8K -1,679 -9%
New York State Common Retirement Fund
123
New York State Common Retirement Fund
New York
$296K
AB
124
Amalgamated Bank
New York
$291K -$2.18K -115 -0.7%
Russell Investments Group
125
Russell Investments Group
United Kingdom
$280K +$203K +10,689 +216%