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Schrodinger

232 hedge funds and large institutions have $1.43B invested in Schrodinger in 2025 Q2 according to their latest regulatory filings, with 44 funds opening new positions, 79 increasing their positions, 77 reducing their positions, and 27 closing their positions.

New
Increased
Maintained
Reduced
Closed

507% more call options, than puts

Call options by funds: $34.7M | Put options by funds: $5.72M

63% more first-time investments, than exits

New positions opened: 44 | Existing positions closed: 27

9% more capital invested

Capital invested by funds: $1.31B → $1.43B (+$120M)

7% more funds holding

Funds holding: 217232 (+15)

6.8% more ownership

Funds ownership: 103.6%110.4% (+6.8%)

3% more repeat investments, than reductions

Existing positions increased: 79 | Existing positions reduced: 77

Holders
232
Holders Change
+15
Holders Change %
+6.91%
% of All Funds
3.05%
Holding in Top 10
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
44
Increased
79
Reduced
77
Closed
27
Calls
$34.7M
Puts
$5.72M
Net Calls
+$29M
Net Calls Change
+$18.8M
Name Holding Trade Value Shares
Change
Change in
Stake
Stifel Financial
101
Stifel Financial
Missouri
$571K +$280K +12,280 +76%
Manulife (Manufacturers Life Insurance)
102
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$571K +$251 +11 +0%
Creative Planning
103
Creative Planning
Kansas
$558K +$37.4K +1,636 +6%
OAM
104
Oxford Asset Management
United Kingdom
$543K +$616K +26,976 New
PWM
105
Palumbo Wealth Management
New York
$534K +$206K +9,025 +52%
LSERS
106
Louisiana State Employees Retirement System
Louisiana
$525K
Ensign Peak Advisors
107
Ensign Peak Advisors
Utah
$516K
IEFM
108
IQ EQ Fund Management
Ireland
$514K +$168K +7,374 +41%
A
109
AlphaQuest
New York
$507K +$104K +4,544 +22%
UOC
110
UBS O'Connor
Illinois
$490K -$792K -34,685 -59%
IMRF
111
Illinois Municipal Retirement Fund
Illinois
$486K +$551K +24,151 New
Zurich Cantonal Bank
112
Zurich Cantonal Bank
Switzerland
$485K +$64.5K +2,823 +13%
SFI
113
Susquehanna Fundamental Investments
Pennsylvania
$479K -$377K -16,499 -41%
GCA
114
Greenwood Capital Associates
South Carolina
$442K -$26.2K -1,146 -5%
PTC
115
Petrus Trust Company
Texas
$426K +$483K +21,177 New
YCM
116
Yousif Capital Management
Michigan
$420K -$1.1K -48 -0.2%
BM
117
Brandywine Managers
Delaware
$420K
CAPTRUST Financial Advisors
118
CAPTRUST Financial Advisors
North Carolina
$417K +$78.1K +3,420 +20%
DekaBank Deutsche Girozentrale
119
DekaBank Deutsche Girozentrale
Germany
$410K
Group One Trading
120
Group One Trading
Illinois
$407K +$163K +7,153 +55%
UAG
121
United Advisor Group
Ohio
$405K +$1.8K +79 +0.4%
Raymond James Financial
122
Raymond James Financial
Florida
$389K -$32.9K -1,441 -7%
HCA
123
Harbor Capital Advisors
Illinois
$383K +$91.6K +4,012 +27%
ASRS
124
Arizona State Retirement System
Arizona
$375K +$9.25K +405 +2%
Comerica Bank
125
Comerica Bank
Texas
$374K -$1.46K -64 -0.3%

SDGR Hedge Fund Activity: Q2 2025 in Review

232 of the 7,595 institutional investors tracked by Wall St. Rank reported a position in Schrodinger (SDGR) for Q2 2025, worth a combined $1.43B — up 9.2% from $1.31B a quarter earlier.

Buyers outnumbered sellers: 44 funds opened new SDGR positions and 27 closed out — a net gain of 17 holders — while 79 added to existing stakes and 77 trimmed.

The largest buyer was Cadian Capital Management, adding an estimated $44.3M. The largest seller was UBS AM, cutting an estimated $21.5M.

  • 232 institutional investors held Schrodinger (SDGR) as of Q2 2025, up from 217 in Q1 2025.
  • Funds reported $1.43B of Schrodinger stock for Q2 2025, up 9.2% quarter-over-quarter.
  • 44 funds opened new Schrodinger positions in Q2 2025 and 27 closed out, a net change of +17 holders.
  • The largest Schrodinger buyer in Q2 2025 was Cadian Capital Management, an estimated $44.3M added.
  • The largest Schrodinger seller in Q2 2025 was UBS AM, an estimated $21.5M sold.

Based on aggregated 13F filings for Q2 2025.