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Schrodinger
SDGR

217 hedge funds and large institutions have $1.31B invested in Schrodinger in 2025 Q1 according to their latest regulatory filings, with 30 funds opening new positions, 75 increasing their positions, 69 reducing their positions, and 22 closing their positions.

New
Increased
Maintained
Reduced
Closed

206% more call options, than puts

Call options by funds: $15.3M | Put options by funds: $5M

36% more first-time investments, than exits

New positions opened: 30 | Existing positions closed: 22

9% more capital invested

Capital invested by funds: $1.19B → $1.31B (+$113M)

6.4% more ownership

Funds ownership: 97.2% → 103.6% (+6.4%)

3% more funds holding

Funds holding: 211 → 217 (+6)

9% more repeat investments, than reductions

Existing positions increased: 75 | Existing positions reduced: 69

Holders
217
Holders Change
+6
Holders Change %
+2.84%
% of All Funds
2.91%
Holding in Top 10
–
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
–
New
30
Increased
75
Reduced
69
Closed
22
Calls
$15.3M
Puts
$5M
Net Calls
+$10.3M
Net Calls Change
+$6.94M

Top Buyers

Rank Fund Capital Flow
1
UBS AM
UBS AM
Illinois
+$61.6M
2
CCM
Cadian Capital Management
New York
+$24.9M
3
American Century Companies
American Century Companies
Missouri
+$22.6M
4
Citadel Advisors
Citadel Advisors
Florida
+$11.9M
5
SIMG
Stephens Investment Management Group
Texas
+$8.15M

Top Sellers

Rank Fund Capital Flow
1
Morgan Stanley
Morgan Stanley
New York
-$8.3M
2
PM
Prosight Management
Texas
-$7.55M
3
BlackRock
BlackRock
New York
-$7.5M
4
Millennium Management
Millennium Management
New York
-$5.9M
5
RCMNY
Rubric Capital Management (New York)
New York
-$4.5M
Name Holding Trade Value Shares
Change 		Change in
Stake
HF
101
HRT Financial
New York
$407K +$465K +20,668 New
Verition Fund Management
102
Verition Fund Management
Connecticut
$396K -$161K -7,177 -26%
UAG
103
United Advisor Group
Ohio
$396K +$6.64K +295 +1%
DekaBank Deutsche Girozentrale
104
DekaBank Deutsche Girozentrale
Germany
$393K – – –
SEI Investments
105
SEI Investments
Pennsylvania
$391K -$11.3K -504 -2%
Russell Investments Group
106
Russell Investments Group
United Kingdom
$390K -$2.39M -106,322 -84%
TRSOTSOK
107
Teachers Retirement System of the State of Kentucky
Kentucky
$385K – – –
Comerica Bank
108
Comerica Bank
Texas
$368K -$10.3K -457 -2%
ASRS
109
Arizona State Retirement System
Arizona
$360K -$4.66K -207 -1%
IEFM
110
IQ EQ Fund Management
Ireland
$359K +$409K +18,178 New
PWM
111
Palumbo Wealth Management
New York
$345K +$394K +17,493 New
CAPTRUST Financial Advisors
112
CAPTRUST Financial Advisors
North Carolina
$342K +$109K +4,844 +39%
Cetera Investment Advisers
113
Cetera Investment Advisers
Illinois
$338K +$385K +17,105 New
EGM
114
Engineers Gate Manager
New York
$337K +$158K +7,002 +69%
New York State Common Retirement Fund
115
New York State Common Retirement Fund
New York
$327K – – –
NIM
116
NEOS Investment Management
Connecticut
$325K -$412K -18,331 -53%
TE
117
Tema ETFs
New York
$325K -$412K -18,331 -53%
Stifel Financial
118
Stifel Financial
Missouri
$318K -$31.3K -1,390 -8%
MSRPS
119
Maryland State Retirement & Pension System
Maryland
$317K -$58.9K -2,618 -14%
AB
120
Amalgamated Bank
New York
$312K -$6.97K -310 -2%
State Board of Administration of Florida Retirement System
121
State Board of Administration of Florida Retirement System
Florida
$307K – – –
Bank of Montreal
122
Bank of Montreal
Ontario, Canada
$297K +$39.3K +1,748 +13%
VOYA Investment Management
123
VOYA Investment Management
Georgia
$296K -$40.9K -1,817 -11%
HCA
124
Harbor Capital Advisors
Illinois
$296K +$82.7K +3,676 +32%
Handelsbanken Fonder
125
Handelsbanken Fonder
Sweden
$282K – – –
3 4
5
6 7

SDGR Hedge Fund Activity: Q1 2025 in Review

217 of the 7,458 institutional investors tracked by Wall St. Rank reported a position in Schrodinger (SDGR) for Q1 2025, worth a combined $1.31B — up 9.5% from $1.19B a quarter earlier.

Buyers outnumbered sellers: 30 funds opened new SDGR positions and 22 closed out — a net gain of 8 holders — while 75 added to existing stakes and 69 trimmed.

The largest buyer was UBS AM, adding an estimated $61.6M. The largest seller was Morgan Stanley, cutting an estimated $8.3M.

  • 217 institutional investors held Schrodinger (SDGR) as of Q1 2025, up from 211 in Q4 2024.
  • Funds reported $1.31B of Schrodinger stock for Q1 2025, up 9.5% quarter-over-quarter.
  • 30 funds opened new Schrodinger positions in Q1 2025 and 22 closed out, a net change of +8 holders.
  • The largest Schrodinger buyer in Q1 2025 was UBS AM, an estimated $61.6M added.
  • The largest Schrodinger seller in Q1 2025 was Morgan Stanley, an estimated $8.3M sold.

Based on aggregated 13F filings for Q1 2025.