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Schrodinger
SDGR

232 hedge funds and large institutions have $1.43B invested in Schrodinger in 2025 Q2 according to their latest regulatory filings, with 44 funds opening new positions, 79 increasing their positions, 77 reducing their positions, and 27 closing their positions.

New
Increased
Maintained
Reduced
Closed

507% more call options, than puts

Call options by funds: $34.7M | Put options by funds: $5.72M

63% more first-time investments, than exits

New positions opened: 44 | Existing positions closed: 27

9% more capital invested

Capital invested by funds: $1.31B → $1.43B (+$120M)

7% more funds holding

Funds holding: 217 → 232 (+15)

6.8% more ownership

Funds ownership: 103.6% → 110.4% (+6.8%)

3% more repeat investments, than reductions

Existing positions increased: 79 | Existing positions reduced: 77

Holders
232
Holders Change
+15
Holders Change %
+6.91%
% of All Funds
3.05%
Holding in Top 10
–
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
–
New
44
Increased
79
Reduced
77
Closed
27
Calls
$34.7M
Puts
$5.72M
Net Calls
+$29M
Net Calls Change
+$18.8M

Top Buyers

Rank Fund Capital Flow
1
CCM
Cadian Capital Management
New York
+$44.3M
2
BlackRock
BlackRock
New York
+$30M
3
FCM
Farallon Capital Management
California
+$25.3M
4
UBS Group
UBS Group
Switzerland
+$21.2M
5
Two Sigma Advisers
Two Sigma Advisers
New York
+$13.6M

Top Sellers

Rank Fund Capital Flow
1
UBS AM
UBS AM
Illinois
-$21.5M
2
TAM
Tocqueville Asset Management
New York
-$16.7M
3
Massachusetts Financial Services
Massachusetts Financial Services
Massachusetts
-$13.7M
4
Citadel Advisors
Citadel Advisors
Florida
-$8.49M
5
Millennium Management
Millennium Management
New York
-$8.39M
Name Holding Trade Value Shares
Change 		Change in
Stake
T. Rowe Price Associates
76
T. Rowe Price Associates
Maryland
$1M +$73.8K +3,232 +7%
SPS
77
Susquehanna Portfolio Strategies
Pennsylvania
$977K +$1.11M +48,542 New
Man Group
78
Man Group
United Kingdom
$940K +$1.07M +46,695 New
New York State Teachers Retirement System (NYSTRS)
79
New York State Teachers Retirement System (NYSTRS)
New York
$924K – – –
VAM
80
Verity Asset Management
North Carolina
$910K +$1.03M +45,251 New
FAM
81
Fred Alger Management
New York
$904K +$1.03M +44,950 New
Voloridge Investment Management
82
Voloridge Investment Management
Florida
$871K +$989K +43,314 New
State of Wisconsin Investment Board
83
State of Wisconsin Investment Board
Wisconsin
$837K -$56.5K -2,473 -6%
Thrivent Financial for Lutherans
84
Thrivent Financial for Lutherans
Minnesota
$827K +$8.58K +376 +0.9%
MAM
85
Monaco Asset Management
Monaco
$805K -$970K -42,500 -52%
SEI Investments
86
SEI Investments
Pennsylvania
$769K +$420K +18,410 +93%
CFM
87
Catalyst Funds Management
Australia
$757K +$858K +37,600 New
IIM
88
INTECH Investment Management
Florida
$756K -$257K -11,254 -23%
Deutsche Bank
89
Deutsche Bank
Germany
$745K -$166K -7,277 -16%
SOADOR
90
State of Alaska Department of Revenue
Alaska
$668K +$57.1K +2,503 +8%
SG Americas Securities
91
SG Americas Securities
New York
$667K +$562K +24,633 +288%
TI
92
TrueMark Investments
Illinois
$666K -$29K -1,272 -4%
VF
93
Virtu Financial
New York
$665K +$755K +33,075 New
MIM
94
MetLife Investment Management
New Jersey
$663K – – –
WG
95
Winton Group
United Kingdom
$619K -$490K -21,465 -41%
BNP Paribas Financial Markets
96
BNP Paribas Financial Markets
France
$606K +$153K +6,719 +29%
Cetera Investment Advisers
97
Cetera Investment Advisers
Illinois
$603K +$294K +12,868 +75%
XT
98
XTX Topco
Cayman Islands
$592K +$360K +15,759 +115%
TC
99
TwinBeech Capital
New York
$592K -$152K -6,643 -18%
State of Tennessee, Department of Treasury
100
State of Tennessee, Department of Treasury
Tennessee
$584K +$363K +15,900 +121%
2 3
4
5 6

SDGR Hedge Fund Activity: Q2 2025 in Review

232 of the 7,595 institutional investors tracked by Wall St. Rank reported a position in Schrodinger (SDGR) for Q2 2025, worth a combined $1.43B — up 9.2% from $1.31B a quarter earlier.

Buyers outnumbered sellers: 44 funds opened new SDGR positions and 27 closed out — a net gain of 17 holders — while 79 added to existing stakes and 77 trimmed.

The largest buyer was Cadian Capital Management, adding an estimated $44.3M. The largest seller was UBS AM, cutting an estimated $21.5M.

  • 232 institutional investors held Schrodinger (SDGR) as of Q2 2025, up from 217 in Q1 2025.
  • Funds reported $1.43B of Schrodinger stock for Q2 2025, up 9.2% quarter-over-quarter.
  • 44 funds opened new Schrodinger positions in Q2 2025 and 27 closed out, a net change of +17 holders.
  • The largest Schrodinger buyer in Q2 2025 was Cadian Capital Management, an estimated $44.3M added.
  • The largest Schrodinger seller in Q2 2025 was UBS AM, an estimated $21.5M sold.

Based on aggregated 13F filings for Q2 2025.