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Schrodinger
SDGR

232 hedge funds and large institutions have $1.43B invested in Schrodinger in 2025 Q2 according to their latest regulatory filings, with 44 funds opening new positions, 79 increasing their positions, 77 reducing their positions, and 27 closing their positions.

New
Increased
Maintained
Reduced
Closed

507% more call options, than puts

Call options by funds: $34.7M | Put options by funds: $5.72M

63% more first-time investments, than exits

New positions opened: 44 | Existing positions closed: 27

9% more capital invested

Capital invested by funds: $1.31B → $1.43B (+$120M)

7% more funds holding

Funds holding: 217 → 232 (+15)

6.8% more ownership

Funds ownership: 103.6% → 110.4% (+6.8%)

3% more repeat investments, than reductions

Existing positions increased: 79 | Existing positions reduced: 77

Holders
232
Holders Change
+15
Holders Change %
+6.91%
% of All Funds
3.05%
Holding in Top 10
–
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
–
New
44
Increased
79
Reduced
77
Closed
27
Calls
$34.7M
Puts
$5.72M
Net Calls
+$29M
Net Calls Change
+$18.8M

Top Buyers

Rank Fund Capital Flow
1
CCM
Cadian Capital Management
New York
+$44.3M
2
BlackRock
BlackRock
New York
+$30M
3
FCM
Farallon Capital Management
California
+$25.3M
4
UBS Group
UBS Group
Switzerland
+$21.2M
5
Two Sigma Advisers
Two Sigma Advisers
New York
+$13.6M

Top Sellers

Rank Fund Capital Flow
1
UBS AM
UBS AM
Illinois
-$21.5M
2
TAM
Tocqueville Asset Management
New York
-$16.7M
3
Massachusetts Financial Services
Massachusetts Financial Services
Massachusetts
-$13.7M
4
Citadel Advisors
Citadel Advisors
Florida
-$8.49M
5
Millennium Management
Millennium Management
New York
-$8.39M
Name Holding Trade Value Shares
Change 		Change in
Stake
Ameriprise
51
Ameriprise
Minnesota
$2.39M -$302K -13,209 -10%
SC
52
Slow Capital
California
$2.09M +$2.37M +103,647 New
GWM
53
Geneos Wealth Management
Colorado
$2.02M -$1.82M -79,613 -44%
EGM
54
Engineers Gate Manager
New York
$1.83M +$1.68M +73,791 +432%
JP Morgan Chase
55
JP Morgan Chase
New York
$1.68M -$520K -22,777 -21%
Capital Fund Management (CFM)
56
Capital Fund Management (CFM)
France
$1.49M +$1.69M +73,838 New
Susquehanna International Group
57
Susquehanna International Group
Pennsylvania
$1.47M -$88.5K -3,878 -5%
AllianceBernstein
58
AllianceBernstein
Tennessee
$1.45M -$151K -6,600 -8%
Citigroup
59
Citigroup
New York
$1.4M -$4.97M -217,607 -76%
BHCM
60
Brevan Howard Capital Management
Jersey
$1.36M +$1.27M +55,774 +463%
Marshall Wace
61
Marshall Wace
United Kingdom
$1.28M +$1.46M +63,833 New
Canada Life
62
Canada Life
Manitoba, Canada
$1.28M -$122K -5,352 -8%
JF
63
Jump Financial
Illinois
$1.25M +$1.41M +61,904 New
First Trust Advisors
64
First Trust Advisors
Illinois
$1.23M +$1.39M +61,000 New
ECM
65
ExodusPoint Capital Management
New York
$1.22M +$1.39M +60,796 New
GCM
66
Graham Capital Management
Connecticut
$1.18M +$1.33M +58,469 New
California State Teachers Retirement System (CalSTRS)
67
California State Teachers Retirement System (CalSTRS)
California
$1.17M -$13K -569 -1%
Mirae Asset Global ETFs Holdings
68
Mirae Asset Global ETFs Holdings
Hong Kong
$1.17M +$569K +24,926 +75%
Prudential Financial
69
Prudential Financial
New Jersey
$1.16M +$80K +3,505 +6%
Balyasny Asset Management
70
Balyasny Asset Management
Illinois
$1.15M +$1.31M +57,254 New
Commonwealth Equity Services
71
Commonwealth Equity Services
Massachusetts
$1.12M -$85.8K -3,757 -6%
Janus Henderson Group
72
Janus Henderson Group
United Kingdom
$1.09M +$590K +25,833 +91%
HSBC Holdings
73
HSBC Holdings
United Kingdom
$1.03M +$1.15M +50,330 New
LPL Financial
74
LPL Financial
California
$1.02M +$231K +10,127 +25%
Wells Fargo
75
Wells Fargo
California
$1.01M -$67.3K -2,946 -6%
1 2
3
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SDGR Hedge Fund Activity: Q2 2025 in Review

232 of the 7,595 institutional investors tracked by Wall St. Rank reported a position in Schrodinger (SDGR) for Q2 2025, worth a combined $1.43B — up 9.2% from $1.31B a quarter earlier.

Buyers outnumbered sellers: 44 funds opened new SDGR positions and 27 closed out — a net gain of 17 holders — while 79 added to existing stakes and 77 trimmed.

The largest buyer was Cadian Capital Management, adding an estimated $44.3M. The largest seller was UBS AM, cutting an estimated $21.5M.

  • 232 institutional investors held Schrodinger (SDGR) as of Q2 2025, up from 217 in Q1 2025.
  • Funds reported $1.43B of Schrodinger stock for Q2 2025, up 9.2% quarter-over-quarter.
  • 44 funds opened new Schrodinger positions in Q2 2025 and 27 closed out, a net change of +17 holders.
  • The largest Schrodinger buyer in Q2 2025 was Cadian Capital Management, an estimated $44.3M added.
  • The largest Schrodinger seller in Q2 2025 was UBS AM, an estimated $21.5M sold.

Based on aggregated 13F filings for Q2 2025.